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Our top choices for Santa Ana hotels

Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.4 out of 10, Good, (63 reviews)
"Excelente "
Mexico
David
Hostal La Cigarra

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (74 reviews)
"We live this property and stay here whenever we are in town."
United States
chris
Casco View Apartments

Hotel República

Hotel República
2.0 star property
Santa Ana
6.6 out of 10, (184 reviews)
"Super outdated. Looks dangerous in the area"
United States
Nina Kristine
Hotel República

La Manzana by Wynwood House

La Manzana by Wynwood House
3.0 star property
Santa Ana
7.2 out of 10, Good, (15 reviews)
"Great hotel. Very close to Casco viejo"
United States
LUCILA
The price is 1.445.467 ₫
2.310.129 ₫ total
includes taxes & fees
1 Mar - 2 Mar
La Manzana by Wynwood House

Taboga Palace Spa Hotel

Taboga Palace Spa Hotel
3.5 star property
17.7 km from Santa Ana
9.2 out of 10, Wonderful, (45 reviews)
"David and his wife provide a truly fantastic at such a quaint and beautiful property. The pool and views are incredible. We are having such a great time and plan to return in the future."
Canada
Marc-Andre
The price is 3.388.840 ₫
3.727.724 ₫ total
includes taxes & fees
26 Feb - 27 Feb
Taboga Palace Spa Hotel

Panama House Bed & Breakfast

Panama House Bed & Breakfast
2.5 star property
Bella Vista, 4.6 km from Santa Ana
9.0 out of 10, Wonderful, (193 reviews)
"Amenities, staff, cleanliness, price all excellent!"
United States
Christopher
Panama House Bed & Breakfast

La Résidence Panamá

La Résidence Panamá
2.5 star property
Campo Alegre, 3.4 km from Santa Ana
9.0 out of 10, Wonderful, (6 reviews)
"EL hotel es nuevo, todo muy lindo. La habitación que me tocó era muy cómoda, pero con solo una pequeña ventana a una zona de servicios... no muy lindo... unica observación El personal sumamente amable"
Mexico
JOAQUIN
The price is 3.393.706 ₫
3.733.077 ₫ total
includes taxes & fees
28 Feb - 1 Mar
La Résidence Panamá

Ramada Panama Centro Via Argentina

Ramada Panama Centro Via Argentina
3.0 star property
El Cangrejo, 3.8 km from Santa Ana
7.4 out of 10, Good, (298 reviews)
"The staff was super friendly "
United States
Anneliase
The price is 1.883.413 ₫
2.071.885 ₫ total
includes taxes & fees
2 Mar - 3 Mar
Ramada Panama Centro Via Argentina

Hotel Montreal

Hotel Montreal
3.5 star property
Bella Vista, 2.7 km from Santa Ana
6.0 out of 10, (405 reviews)
"The hotel was as I expected. Nothing fancy but clean, comfortable, with easy access from the city. There was parking always available. The restaurant, bar, and the pool were open. The people who worked there had the best predisposition to help and make our time in the hotel great. "
United States
Maria Eugenia Fourcade
Hotel Montreal

Crowne Plaza Panama by IHG

Crowne Plaza Panama by IHG
4.0 star property
Bella Vista, 3.2 km from Santa Ana
8.0 out of 10, Very good, (223 reviews)
"Staff were amazing . Great breakfast and convenient area close to the train station "
United States
Darius
The price is 2.481.674 ₫
2.729.841 ₫ total
includes taxes & fees
28 Feb - 1 Mar
Crowne Plaza Panama by IHG

Toscana Inn

Toscana Inn
3.5 star property
El Cangrejo, 3.7 km from Santa Ana
8.8 out of 10, Excellent, (740 reviews)
"Very good spot for the price. Very close to everything. "
United States
Kartar
The price is 2.387.047 ₫
2.625.830 ₫ total
includes taxes & fees
26 Feb - 27 Feb
Toscana Inn

Hilton Garden Inn Panama City Downtown, Panama

Hilton Garden Inn Panama City Downtown, Panama
3.5 star property
El Cangrejo, 3.4 km from Santa Ana
8.6 out of 10, Excellent, (1,007 reviews)
"Staff very friendly. Good breakfast. "
Canada
Liam
The price is 2.244.455 ₫
2.468.900 ₫ total
includes taxes & fees
14 Mar - 15 Mar
Hilton Garden Inn Panama City Downtown, Panama

Hotel y Casino Central Park Panama

Hotel y Casino Central Park Panama
3.0 star property
Bethania, 5.6 km from Santa Ana
7.6 out of 10, Good, (439 reviews)
"Great service, clean, great location "
United States
EDGAR
The price is 1.689.195 ₫
1.858.115 ₫ total
includes taxes & fees
26 Feb - 27 Feb
Hotel y Casino Central Park Panama

MARINN PLACE Financial District

MARINN PLACE Financial District
3.5 star property
Campo Alegre, 3.3 km from Santa Ana
9.0 out of 10, Wonderful, (317 reviews)
"Second stay, very nice"
Canada
Xiaozhi
MARINN PLACE Financial District

Villa Caprichosa

Villa Caprichosa
3.0 star property
18.3 km from Santa Ana
9.8 out of 10, Exceptional, (51 reviews)
"Nice view of the beach "
United States
Lourdes
The price is 6.546.500 ₫
7.201.150 ₫ total
includes taxes & fees
26 Feb - 27 Feb
Villa Caprichosa

Gran Evenia Panama

Gran Evenia Panama
4.5 star property
El Cangrejo, 3.8 km from Santa Ana
9.2 out of 10, Wonderful, (220 reviews)
"Great location and great staff. "
United States
Shaunqualia Lakice
Gran Evenia Panama

Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
El Cangrejo, 3.4 km from Santa Ana
8.8 out of 10, Excellent, (509 reviews)
"Excellent place, friendly staff, great breakfast and many shops close by. "
United States
Raymond
Torres de Alba Hotel & Suites

Hampton by Hilton Panama

Hampton by Hilton Panama
3.0 star property
El Cangrejo, 3.8 km from Santa Ana
7.8 out of 10, Good, (1,006 reviews)
"The room was spotless and the staff was wonderful"
United States
Kenesha
The price is 1.923.818 ₫
2.116.200 ₫ total
includes taxes & fees
7 Mar - 8 Mar
Hampton by Hilton Panama

Metro Hotel Panama

Metro Hotel Panama
3.5 star property
El Cangrejo, 3.7 km from Santa Ana
7.8 out of 10, Good, (410 reviews)
"Clean room and good staff"
United States
Afsana
Metro Hotel Panama

Tantalo Hotel

Tantalo Hotel
3.5 star property
San Felipe, 0.7 km from Santa Ana
8.8 out of 10, Excellent, (286 reviews)
"Amazing room, very spacious with a nice balcony, super clean, AC worked perfect, 10/10 everything. "
Canada
Anupam
Tantalo Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, pool loungers
Casco View Apartments
3.5 star property
9.0
Wonderful
74 reviews
View
Bar (on property)
Hostal La Cigarra
2.0 star property
7.4
Good
63 reviews
View
Apartment (20) | Iron/ironing board, free WiFi, bed sheets
La Manzana by Wynwood House
3.0 star property
7.2
Good
15 reviews
View
Double Room | View from room
Hotel República
2.0 star property
6.6
184 reviews
View
Café
Hotel Doral
2.5 star property
6.2
29 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Crown Casino.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Cinta Costera and Avenida Balboa while you're in the neighbourhood.
How many hotels can I expect to find in Santa Ana?
Expedia has 88 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.
What is there to do in this Panama City neighbourhood?
If you're looking forward to a day of shopping in Santa Ana, consider Avenida Central or Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighbourhood. Albrook Shopping Mall, Amador Theater and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.

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