Santa Ana Travel Guide

Antigua Guatemala

A white colonial church with ornate architecture and a large wooden door.


Top hotels in Santa Ana

Barceló Guatemala City

Barceló Guatemala City

4.5 out of 5
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
The price is 2.559.586 ₫ per night from 26 Oct to 27 Oct
2.559.586 ₫
3.122.695 ₫ total
26 Oct - 27 Oct
includes taxes & fees
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the pool in their reviews. ...
9.2/10 Wonderful! (3,307 reviews)
"This is a great hotel in Guatemala City. Extremely convenient location - close to airport, walking to shopping, restaurants, entertainment. Super helpful staff. Clean facilities. Outstanding breakfast. Just can't find anything negative to say about it. It will be our new home away from home in Guate. ..."

Reviewed on 15 Oct 2026

Barceló Guatemala City
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

4.5 out of 5
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
The price is 6.382.624 ₫ per night from 18 Oct to 19 Oct
6.382.624 ₫
8.102.696 ₫ total
18 Oct - 19 Oct
includes taxes & fees
Stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa and 2 restaurants. Our guests praise the helpful staff and the property ...
Hotel Museo Spa Casa Santo Domingo
Wyndham Garden Guatemala City

Wyndham Garden Guatemala City

4 out of 5
1a Avenida 12-46 Zona 10 Guatemala City Guatemala
The price is 2.420.995 ₫ per night from 1 Nov to 2 Nov
2.420.995 ₫
2.953.614 ₫ total
1 Nov - 2 Nov
includes taxes & fees
Stay at this business-friendly hotel in Guatemala City. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,943 reviews)
"No le funcionaba el agua caliente me tuve que duchar con agua tibia."

Reviewed on 15 Oct 2026

Wyndham Garden Guatemala City
Adriatika Hotel & Residence

Adriatika Hotel & Residence

4.5 out of 5
4 av 20-44 Zona 14 Guatemala City Guatemala
The price is 2.834.895 ₫ per night from 23 Oct to 24 Oct
2.834.895 ₫
3.458.572 ₫ total
23 Oct - 24 Oct
includes taxes & fees
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
Adriatika Hotel & Residence
Hotel Camino Real Antigua

Hotel Camino Real Antigua

4 out of 5
7a Calle Poniente 33B Antigua Guatemala Sacatepequez
The price is 4.893.777 ₫ per night from 18 Oct to 19 Oct
4.893.777 ₫
6.617.733 ₫ total
18 Oct - 19 Oct
includes taxes & fees
Stay at this spa hotel in Antigua Guatemala. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
9.6/10 Exceptional! (1,000 reviews)
"Everyone there were so friendly, helpful, polite. The hotel is beautiful, close to everything. I will come back to Antigua and stay again in Camino Real. Gorgeous. Good location, amazing 👏"

Reviewed on 14 Oct 2026

Hotel Camino Real Antigua
Hotel Biltmore Guatemala

Hotel Biltmore Guatemala

3.5 out of 5
15 Calle 0-31, Zona 10 Guatemala City Guatemala
The price is 2.283.763 ₫ per night from 1 Nov to 2 Nov
2.283.763 ₫
2.786.191 ₫ total
1 Nov - 2 Nov
includes taxes & fees
Stay at this business-friendly hotel in Guatemala City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff in their ...
9.4/10 Exceptional! (1,000 reviews)
"Excellent place to stay! In the heart of a livley zone and within walking distance from restaurants and malls. And just a few minutes from even more things to do."

Reviewed on 13 Oct 2026

Hotel Biltmore Guatemala
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Historic Center

If you're spending some time in Historic Center, Central Park and Santa Catalina Arch are top sights worth seeing.

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.



Santa Ana Travel Guide

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