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Our top choices for Santa Croce hotels

Hotel Antiche Figure

Hotel Antiche Figure
3.0 star property
Santa Croce
9.8 out of 10, Exceptional, (1005)
"Staff were excellent, we loved the location. "
Canada
Barry
Hotel Antiche Figure

Hotel Aquarius Venice

Hotel Aquarius Venice
4.0 star property
Santa Croce
9.6 out of 10, Exceptional, (414)
"excellent choice, the hotel looks like brand new, convenient location at a beautiful plazza, staff is super nice grest food"
United States
victor
The price is 2.801.256 ₫
3.358.705 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Hotel Aquarius Venice

Hotel Olimpia Venice, BW Signature Collection

Hotel Olimpia Venice, BW Signature Collection
3.5 star property
Santa Croce
9.6 out of 10, Exceptional, (1002)
"Amazing rooms, staff and breakfast! Highly recommend and definitely will return!"
United States
Ruby
The price is 3.501.570 ₫
3.999.633 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hotel Olimpia Venice, BW Signature Collection

Hotel Carlton on the Grand Canal

Hotel Carlton on the Grand Canal
4.0 star property
Santa Croce
8.4 out of 10, Very good, (1003)
"Friendly staff, clean rooms, excellent location! "
United States
Inna
Hotel Carlton on the Grand Canal

Palazzo Odoni

Palazzo Odoni
Santa Croce
9.4 out of 10, Exceptional, (547)
"The hotel was beautiful. The staff were very friendly and helpful. Great location. I would definitely stay there again. I highly recommend "
Australia
Diana
Palazzo Odoni

Santa Croce Boutique Hotel

Santa Croce Boutique Hotel
4.5 star property
Santa Croce
10.0 out of 10, Exceptional, (478)
"We loved the location "
United States
Jonathan
Santa Croce Boutique Hotel

Santa Chiara Hotel

Santa Chiara Hotel
4.5 star property
Santa Croce
9.4 out of 10, Exceptional, (319)
"Conveniently located next to the main bus terminal and a good launching point to the city. The staff was super kind and helpful. "
United States
Jeremy
The price is 5.619.319 ₫
6.458.575 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Santa Chiara Hotel

Carlton Capri Hotel

Carlton Capri Hotel
3.0 star property
Santa Croce
8.2 out of 10, Very good, (733)
"clean room and helpful staff"
Canada
gina
The price is 2.013.375 ₫
2.430.409 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Carlton Capri Hotel

Hotel Arlecchino

Hotel Arlecchino
3.0 star property
Santa Croce
9.2 out of 10, Wonderful, (1000)
"Very friendly staff and excellent location!"
United States
renuka
The price is 4.024.004 ₫
4.642.101 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Hotel Arlecchino

Ac Hotel Venezia by Marriott

Ac Hotel Venezia by Marriott
3.0 star property
Santa Croce
9.4 out of 10, Exceptional, (386)
"Great hotel in a great location. "
United States
EMILY
The price is 4.738.325 ₫
5.360.063 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Ac Hotel Venezia by Marriott

Hotel San Cassiano Ca'Favretto

Hotel San Cassiano Ca'Favretto
4.0 star property
Santa Croce
8.8 out of 10, Excellent, (1000)
"Outstanding staff, breakfast, location & view."
United States
Nissim
Hotel San Cassiano Ca'Favretto

Hotel Al Duca Di Venezia

Hotel Al Duca Di Venezia
3.0 star property
Santa Croce
9.2 out of 10, Wonderful, (1001)
"Rooms were very clean and hotel was in a great spot close to the train station and the water taxis. Hotel staff were very welcoming. "
United States
Kara
Hotel Al Duca Di Venezia

Papadopoli Hotel Venezia - MGallery Collection

Papadopoli Hotel Venezia - MGallery Collection
4.0 star property
Santa Croce
9.2 out of 10, Wonderful, (1001)
"Not the most central of locations, but you can get a water taxi right to the hotel to go anywhere, and the room service is wonderful!"
United States
Mary
The price is 4.762.135 ₫
5.429.395 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Papadopoli Hotel Venezia - MGallery Collection

Residenza degli Angeli

Residenza degli Angeli
Santa Croce
9.4 out of 10, Exceptional, (1001)
"This place is a gem. The hosts are very welcoming and have great local recommendations. You are close to the main attractions, but far enough away that you can avoid the crowds if you’d like. "
United States
Makena
The price is 1.316.674 ₫
1.534.528 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Residenza degli Angeli

Albergo Marin

Albergo Marin
1.0 star property
Santa Croce
8.6 out of 10, Excellent, (621)
"We loved staying here! The staff went above and beyond with breakfast and showing us where to go in Venice. We stayed in a quiet neighborhood which was lovely. Everything was clean. "
United States
Joy
The price is 1.964.381 ₫
2.222.447 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Albergo Marin

Casa Sant'Andrea

Casa Sant'Andrea
Santa Croce
8.0 out of 10, Very good, (620)
"Staff was excellent and vary pleasant"
Canada
John
Casa Sant'Andrea

Hotel Ca' Zusto Venezia

Hotel Ca' Zusto Venezia
4.0 star property
Santa Croce
9.4 out of 10, Exceptional, (1000)
"The breakfast was great and the staff were very friendly and helpful. "
Canada
Maureen
The price is 6.162.455 ₫
7.056.055 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hotel Ca' Zusto Venezia

Hotel Palazzo Martinelli Dolfin

Hotel Palazzo Martinelli Dolfin
3.0 star property
Santa Croce
8.0 out of 10, Very good, (150)
"We loved our stay in Venice the property is good but be prepared as it is not a hotel with staff. The check out is 10 am and the only luggage storage is “unattended” which we were told about in advance. "
United States
Christine
The price is 2.088.290 ₫
2.512.816 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Hotel Palazzo Martinelli Dolfin

Ca' Nigra Lagoon Resort

Ca' Nigra Lagoon Resort
4.0 star property
Santa Croce
9.2 out of 10, Wonderful, (366)
"Great facility, staff extremely friendly and nice"
United States
Jorge
The price is 4.432.651 ₫
5.066.962 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Ca' Nigra Lagoon Resort

Hotel Al Ponte Mocenigo

Hotel Al Ponte Mocenigo
3.0 star property
Santa Croce
9.6 out of 10, Exceptional, (722)
"The beds were comfortable, hotel was conveniently near the water bus, and lots to do within walking distance. We like the historic feel od the rooms, and staff was very helpful. "
United States
Naomi
Hotel Al Ponte Mocenigo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Croce

Find the best Santa Croce areas for the activities you enjoy most.

Venice City Center

The stunning cathedral and charming cafes are just a few highlights of Venice City Center. Make a stop by St. Mark's Square or Palazzo Contarini del Bovolo while you're exploring the area.

San Marco

San Marco is beloved for its popular shops. Take some time to explore sights in the area like St. Mark's Square and Palazzo Contarini del Bovolo.

San Polo

San Polo is known for its abundant dining options, and you can plan a trip to Campo San Polo and Basilica di Santa Maria Gloriosa dei Frari while you're in town.

Cannaregio

A noteworthy feature of Cannaregio is its popular shops. While you're in town, be sure to stop and check out Casino of Venice and Ca' d'Oro Giorgio Franchetti Gallery.

Dorsoduro

The ample dining options and fascinating museums are top of the list for many visitors to Dorsoduro. A stop by Maritime Station or Campo Santa Margherita might round out your trip.

Top Santa Croce Hotel Reviews

Frequently asked questions

What's it like in Santa Croce?
Santa Croce is a welcoming neighbourhood known for its charming cafes. Looking for sights you might find in a travel guide about Santa Croce? Consider a visit to Piazzale Roma while you're in the neighbourhood.
How many hotels should I expect to find in Santa Croce?
If you're searching for places to stay in Venice, Expedia has something to meet your needs with 280 Santa Croce hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Santa Croce, will I receive a refund?
Yes! The majority of room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to get top deals in Santa Croce.
What is there to do in this Venice neighbourhood?
Browse the collections at Ca' Pesaro Galleria Internazionale d'Arte Moderna, Venetian Museum of Natural History or Fondaco dei Turchi in Santa Croce. Piazzale Roma and Grand Canal are also a couple of places to visit in the neighbourhood. St. Mark's Square, Ponte di Calatrava and Tolentini are just a few of the places to visit in and around Santa Croce. When you're sightseeing in Venice, Scuola Grande di San Giovanni Evangelista and Scalzi Bridge are also worth a stop.