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Our top choices for Santorini business-friendly hotels

Ira Hotel & Spa - Adults Only

Ira Hotel & Spa - Adults Only
4.0 star property
Santorini
9.4 out of 10, Exceptional, (1000)
"Cleaning service provided daily, all hotel staff was very kind and professional. "
United States
EBONY
The price is 2.617.767 ₫
3.065.769 ₫ total
includes taxes & fees
20 Jan - 21 Jan 2026
Ira Hotel & Spa - Adults Only

Dreams Luxury Suites

Dreams Luxury Suites
Santorini
9.8 out of 10, Exceptional, (192)
"We had an amazing stay here. It’s the perfect location and the staff was so nice !!! "
Canada
Isabella
The price is 4.176.773 ₫
4.758.850 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Dreams Luxury Suites

Summer Lovers Villa

Summer Lovers Villa
Santorini
9.6 out of 10, Exceptional, (18)
"We booked the entire villa for our family and even exchanged our vows on the property—it was truly magical. Miss Marita was amazing, taking care of us in every possible way. We couldn’t have been happier with our stay and hope to return soon. If you’re looking for a private, unforgettable family getaway, I highly recommend Summer Lovers Villa."
United States
zuzana
The price is 3.435.819 ₫
3.917.371 ₫ total
includes taxes & fees
10 Jan - 11 Jan 2026
Summer Lovers Villa

Athina Luxury Suites

Athina Luxury Suites
Santorini
9.4 out of 10, Exceptional, (477)
"Everything about the stay was amazing. We loved the stay and would love to come back"
United Kingdom
Sabiha
The price is 5.303.481 ₫
6.038.382 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Athina Luxury Suites

De Sol Spa Hotel

De Sol Spa Hotel
5.0 star property
Santorini
9.4 out of 10, Exceptional, (525)
"The rooms were clean and the service outstanding. "
United States
Teresa
The price is 4.744.702 ₫
5.512.189 ₫ total
includes taxes & fees
27 Dec - 28 Dec
De Sol Spa Hotel

Smaro Studios

Smaro Studios
Santorini
9.8 out of 10, Exceptional, (202)
"We had a great stay. Staff was very nice and welcoming to us. Explain everything. Great location and easy to walk to many places. "
United States
olga
The price is 4.417.481 ₫
5.032.196 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Smaro Studios

Aelia Luxury Suites

Aelia Luxury Suites
Santorini
8.8 out of 10, Excellent, (16)
"We really had nice stay during our trip to beautiful Santorini! "
Canada
Lobsang
Aelia Luxury Suites

Asha Luxury Suites

Asha Luxury Suites
Santorini
9.6 out of 10, Exceptional, (246)
"Absolutely amazing hotel in Santorini. Fantastic room, very clean, unbelievable views and amazing staff... complete with a bottle of Prosecco and tasty made to order breakfast every morning. "
Canada
Joel
The price is 4.421.646 ₫
5.036.941 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Asha Luxury Suites

Villa Agas

Villa Agas
Santorini
8.0 out of 10, Very good, (193)
"Enjoyed our stay at the Villa Agas - nice and quiet and within walking distance of several restaurants and bakeries. Would recommend others to stay there!"
United States
Sondra
The price is 954.414 ₫
1.099.364 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Villa Agas

Santorini Main Square

Santorini Main Square
Santorini
9.2 out of 10, Wonderful, (58)
"Perfect location, amazing host"
United States
SALEH
Santorini Main Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santorini Hotel Reviews

Frequently asked questions

Why book your business-friendly hotel in Santorini with Expedia?
With top amenities like conference rooms, housekeeping and on-site restaurants, our business-friendly stays come with all you'll need to complete the job — and then relax! Enter your destination and travel dates and Expedia will help you plan everything else.
How can I find cheap business-friendly hotels in Santorini?
Select the "business friendly" filter, listed under the "traveller experience" heading, to find cheap business-friendly hotels in Santorini. Then refine your search by your budget and preferred hotel star rating. Looking for properties away from the centre is another way to save.