The Best Hotels in Serra Highlands, San Francisco - 2026 Updated Prices

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Our top choices for Serra Highlands hotels

A multi-level hotel atrium with outdoor seating areas, a pool, and a central lounge.

1. Embassy Suites by Hilton San Francisco Airport Oyster Point

The East Side, 4.3 km from Serra Highlands

Fan

4.229.349 ₫ total

includes taxes & fees

16 Oct - 17 Oct

An outdoor patio with round tables and chairs, a view of the sea, and parked cars in the background.

2. Bay Landing San Francisco Airport Hotel

9.8 km from Serra Highlands

James

4.152.345 ₫ total

includes taxes & fees

4 Oct - 5 Oct

3. Sonesta Select San Francisco Airport Oyster Point Waterfront

Oyster Point, 5 km from Serra Highlands

Sheila Marie

3.731.111 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A bar area with a curved wooden counter, bar stools, and a glass display case filled with bottles.

4. Best Western Plus Grosvenor Airport Hotel

4.3 km from Serra Highlands

Larry

3.327.133 ₫ total

includes taxes & fees

16 Oct - 17 Oct

A modern hotel entrance with a covered waiting area, glass doors, and a clear sky.

5. Aloft by Marriott San Francisco Airport

8.7 km from Serra Highlands

ross

4.288.788 ₫ total

includes taxes & fees

2 Oct - 3 Oct

A La Quinta hotel with a modern facade, a covered entrance, and a parking lot.

6. La Quinta Inn & Suites by Wyndham San Francisco Airport N

Downtown South San Francisco, 3.8 km from Serra Highlands

Melissa

3.669.211 ₫ total

includes taxes & fees

24 Oct - 25 Oct

A spacious lobby with a reception desk, seating area, and a high ceiling with chandeliers.

7. La Quinta Inn & Suites by Wyndham San Francisco Airport West

6.7 km from Serra Highlands

Francis

4.195.174 ₫ total

includes taxes & fees

24 Oct - 25 Oct

A hotel room with a bed, desk, chair, television, and a microwave.

8. Hotel Nova SFO

4.4 km from Serra Highlands

Chintan

3.552.139 ₫ total

includes taxes & fees

2 Oct - 3 Oct

A spacious, well-lit atrium with a high ceiling and skylight, featuring a central seating area with a sofa and armchairs, surrounded by a patterned rug.

9. Hotel Aluxor SFO

5 km from Serra Highlands

Kenna

3.207.789 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A hotel entrance with a glass facade, outdoor seating, and a landscaped garden area.

10. Hilton San Francisco Airport Bayfront

12 km from Serra Highlands

William

3.608.113 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A modern lobby with a cityscape mural, a reception desk, seating area, and a door with blinds.

11. Hotel Skye SFO

5.1 km from Serra Highlands

GABRIEL

3.770.386 ₫ total

includes taxes & fees

4 Oct - 5 Oct

A hotel lobby with a central reception desk, large columns, and hanging pendant lights.

12. Hilton Garden Inn San Francisco Arpt North

The East Side, 4.6 km from Serra Highlands

Karina

3.345.492 ₫ total

includes taxes & fees

4 Oct - 5 Oct

A courtyard with outdoor seating, a glass table, and potted plants.

13. Comfort Inn and Suites San Francisco Airport North

The East Side, 4 km from Serra Highlands

Sarah

3.126.724 ₫ total

includes taxes & fees

16 Oct - 17 Oct

A reception area with a counter, two patterned chairs, a yellow ottoman, and a large blue potted plant.

14. Hotel Aura SFO

5.7 km from Serra Highlands

Charles

3.482.951 ₫ total

includes taxes & fees

4 Oct - 5 Oct

An outdoor patio with wooden furniture, a chessboard, and hanging floral decorations.

15. The Millwood - A Boutique Hotel

6.8 km from Serra Highlands

Jennifer

4.537.398 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A modern outdoor lounge area with seating, fire pits, and large umbrellas.

16. DoubleTree by Hilton San Francisco Airport

11.4 km from Serra Highlands

Martin

3.789.664 ₫ total

includes taxes & fees

3 Oct - 4 Oct

A hotel room with a bed, a sofa, a nightstand, and a desk. There are three framed pictures on the wall.

17. The Atrium Hotel

4.7 km from Serra Highlands

Ramesh

3.911.589 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A multi-level hotel atrium with a central open space, multiple seating areas, and a glass ceiling.

18. Hyatt Regency San Francisco Airport

10.2 km from Serra Highlands

Christopher

6.497.013 ₫ total

includes taxes & fees

23 Oct - 24 Oct

A hotel with a modern facade, multiple floors, and a well-lit entrance.

19. The Westin San Francisco Airport

8.8 km from Serra Highlands

Mike

4.464.335 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A dining table with a bowl of fruit, a bottle of wine, and two wine glasses.

20. The Marina Inn on San Francisco Bay

23.4 km from Serra Highlands

Sofia

2.642.724 ₫ total

includes taxes & fees

27 Sept - 28 Sept

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Where to stay in Serra Highlands

Find the best Serra Highlands areas for the activities you enjoy most.

A pier with a large number of sea lions resting on floating platforms.

Fisherman's Wharf

Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and San Francisco Bay.

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A cityscape with tall buildings, a central plaza with palm trees, and a flag on one of the buildings.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

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A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

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A cityscape with modern skyscrapers, a central park with pathways, and a few people walking.

South of Market

Gourmet restaurants great entertainment and top sights from Oracle Park to Chase Center – discover South of Market, a destination also famous for its shopping.

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A street lined with historic buildings, parked cars, and a clear blue sky.

Nob Hill

Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.

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Top Serra Highlands Hotel Reviews

Hyatt Place San Francisco Downtown

10/10 Excellent

"My tv remote didn’t work"

Hilton San Francisco Union Square

8/10 Good

"The reason for 4 stars in an otherwise great hotel is that the bathroom doors in our room were not staying shut because the spring on the door was broken. Upon confirming that it could not be fixed, we were allotted a different room. The front desk was really helpful in getting this sorted, kudos to them. I am taking away the one star for the inconvenience we faced."

Frequently asked questions

What is Serra Highlands like?

Travellers to South San Francisco's Serra Highlands neighbourhood will be sure to enjoy a stay here.

How many hotels will I find in the Serra Highlands area?

Book one of Expedia's 5 hotels and other accommodation options in Serra Highlands and start exploring everything South San Francisco has to offer.

If I need to cancel my hotel reservation in Serra Highlands, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the best deals in Serra Highlands.

What is there to do in this South San Francisco neighbourhood?

Cypress Lawn Memorial Park, Hills of Eternity Memorial Park and Wyatt Earp's Grave are just a few of the places to visit in and around Serra Highlands. While you're out sightseeing, Pet's Rest Cemetery and Serramonte Center are a couple of additional sights to visit in South San Francisco.

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Our top choices for Serra Highlands hotels

1. Embassy Suites by Hilton San Francisco Airport Oyster Point

2. Bay Landing San Francisco Airport Hotel

3. Sonesta Select San Francisco Airport Oyster Point Waterfront

4. Best Western Plus Grosvenor Airport Hotel

5. Aloft by Marriott San Francisco Airport

6. La Quinta Inn & Suites by Wyndham San Francisco Airport N

7. La Quinta Inn & Suites by Wyndham San Francisco Airport West

8. Hotel Nova SFO

9. Hotel Aluxor SFO

10. Hilton San Francisco Airport Bayfront

11. Hotel Skye SFO

12. Hilton Garden Inn San Francisco Arpt North

13. Comfort Inn and Suites San Francisco Airport North

14. Hotel Aura SFO

15. The Millwood - A Boutique Hotel

16. DoubleTree by Hilton San Francisco Airport

17. The Atrium Hotel

18. Hyatt Regency San Francisco Airport

19. The Westin San Francisco Airport

20. The Marina Inn on San Francisco Bay

Where to stay in Serra Highlands

Fisherman's Wharf

Union Square

Downtown San Francisco

South of Market

Nob Hill

Top Serra Highlands Hotel Reviews

Hyatt Place San Francisco Downtown

Frequently asked questions

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