Find hotels in Sikeston, MO from 1.825.322 ₫
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Sikeston
Pet friendly
Apartment
Condo
Family friendly
Cottage
Waterpark
Check prices for these dates
Tonight
25 Aug - 26 AugTomorrow
26 Aug - 27 AugThis weekend
28 Aug - 30 AugNext weekend
4 Sep - 6 SepOur top choices for Sikeston hotels
1. Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
Sally
2.454.643 ₫
2.822.226 ₫ total
includes taxes & fees
30 Aug - 31 Aug
2. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
Matthew
2.611.339 ₫
2.945.956 ₫ total
includes taxes & fees
6 Sept - 7 Sept
3. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
ELAINE
2.668.524 ₫
3.010.470 ₫ total
includes taxes & fees
22 Sept - 23 Sept
4. The Riverview
The RiverviewCape Girardeau
Alyssa
2.985.059 ₫
3.367.565 ₫ total
includes taxes & fees
27 Aug - 28 Aug
5. Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
Taylor
3.267.112 ₫
3.702.095 ₫ total
includes taxes & fees
6 Sept - 7 Sept
6. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
Shawn
2.312.721 ₫
2.502.943 ₫ total
includes taxes & fees
26 Aug - 27 Aug
7. Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
Bonnie
1.880.091 ₫
2.121.006 ₫ total
includes taxes & fees
30 Aug - 31 Aug
8. Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
Rebekah
2.762.550 ₫
3.116.544 ₫ total
includes taxes & fees
2 Sept - 3 Sept
9. Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape GirardeauJackson
VICTORIA
2.183.203 ₫
2.362.714 ₫ total
includes taxes & fees
24 Sept - 25 Sept
10. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
Sharika West
1.788.685 ₫
2.038.654 ₫ total
includes taxes & fees
20 Sept - 21 Sept
11. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
Jamie
2.167.367 ₫
2.291.449 ₫ total
includes taxes & fees
30 Aug - 31 Aug
12. Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner AreaSikeston
Kevin
1.601.114 ₫
1.825.322 ₫ total
includes taxes & fees
26 Aug - 27 Aug
13. Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
michael
2.742.180 ₫
3.104.834 ₫ total
includes taxes & fees
20 Sept - 21 Sept
14. Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
Allen
2.642.362 ₫
2.991.813 ₫ total
includes taxes & fees
13 Sept - 14 Sept
15. The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-SikestonCharleston
Bobby
1.739.511 ₫
1.930.232 ₫ total
includes taxes & fees
7 Sept - 8 Sept
16. Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
Gwendolyn
2.334.248 ₫
2.656.700 ₫ total
includes taxes & fees
6 Sept - 7 Sept
17. Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHGCape Girardeau
Samuel
2.298.208 ₫
2.736.338 ₫ total
includes taxes & fees
6 Sept - 7 Sept
18. Hampton Inn Sikeston
Hampton Inn SikestonSikeston
Jeffrey
2.655.475 ₫
3.006.661 ₫ total
includes taxes & fees
20 Sept - 21 Sept
19. Econo Lodge Dexter
Econo Lodge DexterDexter
Herman
1.334.000 ₫
1.497.922 ₫ total
includes taxes & fees
24 Sept - 25 Sept
20. TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
Lauren
3.087.116 ₫
3.495.387 ₫ total
includes taxes & fees
3 Sept - 4 Sept
Stay near popular Sikeston attractions
Sikeston Depot Museum
7.6/10 (57 reviews)
Housed in a restored 1916 train depot, this museum showcases Sikeston's cotton-growing heritage and local art. Explore regional history through rotating exhibits while admiring the building's National Register status.
Central Park
7.2/10 (56 reviews)
Central Park offers a peaceful retreat with playgrounds and open spaces for Sikeston families. Bring a blanket for a relaxing picnic or watch children enjoy the recreational facilities.
City of Miner Convention Center
This versatile 16,000-square-foot venue in Miner, Missouri hosts conferences, weddings, and community gatherings. Modern meeting rooms and a commercial kitchen make it ideal for various events.
Sikeston and related destinations
Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.
See all hotels in Sikeston
Top Sikeston Hotel Reviews
Drury Plaza Hotel Cape Girardeau Conference Center
10/10 Excellent
"Very nice hotel......................"
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
10/10 Excellent
"Great hotel very clean great food"
Super 8 by Wyndham Sikeston/Miner Area
10/10 Excellent
"Staff were friendly, room was nice and clean, the breakfast was delicious. Of the three hotels on this trip this was the best one."
Hampton Inn Sikeston
10/10 Excellent
"👍"
Best Western Plus Sikeston I-55
10/10 Excellent
"I really loved everything about my stay and the hotel in general. Nice Job"
The Riverview
8/10 Good
"Nice view of the river. The staff was nice."
Drury Inn & Suites Sikeston, MO
10/10 Excellent
"Great value, very clean and breakfast was actually good."
Days Inn and Suites by Wyndham Sikeston
10/10 Excellent
"We stay here every time we are in Sikesons. Can't beat this hotel. Super clean 'comfortable!' beds, living room area, and bathrooms. Small hot breakfast. All for the best price out there. Don't skip on this hotel! Staff is always polite and helpful. We always love to walk out to the pond"
More cheap stays in Sikeston
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
1.645.851 ₫
1.875.859 ₫ total
27 Aug - 28 Aug
includes taxes & fees
7.2/10 Good! (1,004 reviews)
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
1.880.091 ₫
2.121.006 ₫ total
30 Aug - 31 Aug
includes taxes & fees
Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd Cape Girardeau MO
2.298.208 ₫
2.736.338 ₫ total
6 Sept - 7 Sept
includes taxes & fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street Cape Girardeau MO
2.668.524 ₫
3.010.470 ₫ total
22 Sept - 23 Sept
includes taxes & fees
Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr Sikeston MO
2.742.180 ₫
3.104.834 ₫ total
20 Sept - 21 Sept
includes taxes & fees
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
120 MUDDY MONSTER ROAD Murphysboro IL
2.982.468 ₫
3.309.942 ₫ total
22 Sept - 23 Sept
includes taxes & fees
9.4/10 Exceptional! (596 reviews)
Hotels in Sikeston with star rating
4 Star Hotels
2 properties
2 Star Hotels
46 properties
