A monument with a statue on top, in front of a large building with columns.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in South Carolina Midlands

Apart hotel

Waterpark

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for South Carolina Midlands hotels

Shaw Air Force Base

1. Hampton Inn & Suites Columbia Killian Road

Columbia

Lorita

3.230.843 ₫ total

includes taxes & fees

26 Jul - 27 Jul

2. Howard Johnson by Wyndham Florence

Florence

Miriam

1.855.023 ₫ total

includes taxes & fees

19 Jul - 20 Jul

3. Springhill Suites by Marriott Columbia near Fort Jackson

Columbia

Ritsuko

2.974.151 ₫ total

includes taxes & fees

9 Aug - 10 Aug

4. Fairfield Inn & Suites by Marriott Santee

Santee

Erik

3.907.784 ₫ total

includes taxes & fees

29 Jul - 30 Jul

5. Hilton Garden Inn Columbia/Harbison

Columbia

Albert

2.813.009 ₫ total

includes taxes & fees

9 Aug - 10 Aug

6. Aiken Midtown Hotel

Aiken

Evelio

2.502.809 ₫ total

includes taxes & fees

19 Jul - 20 Jul

7. Holiday Inn Express North Augusta by IHG

North Augusta

Grady

3.183.208 ₫ total

includes taxes & fees

24 Jul - 25 Jul

Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free WiFi

8. Baymont by Wyndham Santee

Santee

Kate

2.330.974 ₫ total

includes taxes & fees

20 Jul - 21 Jul

9. Country Inn & Suites by Radisson, Aiken South

Aiken

John

2.641.031 ₫ total

includes taxes & fees

5 Aug - 6 Aug

10. Hampton Inn Santee-I-95

Santee

Gloria

3.681.069 ₫ total

includes taxes & fees

9 Aug - 10 Aug

11. Best Western Plus Santee Inn

Santee

Lorraine

3.418.512 ₫ total

includes taxes & fees

30 Jul - 31 Jul

12. Park Inn by Radisson Florence, SC

Florence

Kimberly

2.629.421 ₫ total

includes taxes & fees

26 Jul - 27 Jul

13. La Quinta Inn by Wyndham Columbia NE/Fort Jackson

Columbia

Franco

2.599.257 ₫ total

includes taxes & fees

9 Aug - 10 Aug

14. Carriage House Inn

Aiken

Melissa

3.218.093 ₫ total

includes taxes & fees

16 Aug - 17 Aug

15. La Quinta Inn & Suites by Wyndham Rock Hill

Rock Hill

Laurel

2.596.448 ₫ total

includes taxes & fees

19 Jul - 20 Jul

16. Fairfield Inn & Suites by Marriott Florence I-20

Florence

Itid

3.478.902 ₫ total

includes taxes & fees

21 Jul - 22 Jul

17. Holiday Inn Express & Suites Columbia-I-20 @ Clemson Rd by IHG

Columbia

matthew

2.940.357 ₫ total

includes taxes & fees

26 Jul - 27 Jul

18. Comfort Inn & Suites Florence Center Area

Florence

Monica

3.258.382 ₫ total

includes taxes & fees

2 Aug - 3 Aug

19. Best Western Rock Hill

Rock Hill

Charmaine

2.256.666 ₫ total

includes taxes & fees

20 Jul - 21 Jul

20. Hampton Inn Rock Hill

Rock Hill

Christine

2.485.131 ₫ total

includes taxes & fees

2 Aug - 3 Aug

View all properties

Holiday Rentals in South Carolina Midlands

Apartment

Easy Access to I-77 & I-20: Columbia Duplex!

Columbia

"Good rental. The only downside was that there was a strong cigar odor the first two days. I also found a few uncleaned hairs lying around on the counter and bed. Other than that, it’s a good home for a quick trip. Especially if you’re visiting for Fort Jackson purposes."

Aparthotel

stayAPT Suites Columbia-Irmo Harbison

Irmo

"The property was clean the kitchen was nice."

Aparthotel

StudioRes by Marriott Columbia Harbison

Columbia

"My family and I stayed here for one night. It was more than accommodating. However, if I wanted to stay longer, I wouldn't chose this location. The staff was friendly and the place is very clean."

Cottage

3 Mi to Marina: Quiet Getaway w/ Deck in Lexington

Lexington

"Very cozy home lots of room and kept clean!"

Aparthotel

stayAPT Suites Rock Hill

Rock Hill

"Would never book here again.. drove 12 hours and when we got into the place it hardly looked cleaned. No one ever came to restock the toiletries or towels etc. Extra sheets that were given for the pull out couch literally had cigarette burn holes in them and there was a sheet left on the pull out couch with fecal stains on it. Upon leaving yesterday we also saw cockroaches. Never again. outrageous price for 3 nights not worth it. Not to mention every time we needed to talk to the front desk no...

Apartment

Backyard Oasis w/ Pool: Sunny Sumter Studio!

Sumter

"The studio was very clean, decorated nicely, and cozy. The location is quiet and easy to find. Communication was punctual. I really enjoyed my stay"

Cottage

Family Home w/ Fire Pit, 2 Mi to Lake Access

Lexington

"Thank you so much for having spices in the drawer"

Cottage

Peaceful Camden Vacation Rental ~ 3 Mi to Town!

Camden

"Location was perfect for us. Very cozy, and clean. Hadn't been modernized, but it was in great shape. Nasolgic; felt like I was visiting my grandparents! Only having one bathroom was a bit challenging, but we made it work!"

Cottage

Lake Access & Boat Slip: Greenwood Cottage!

Greenwood

"Outstanding little cottage for my mom and daughter weekend! Super clean and comfortable. "

Cottage

Lake Marion Canal Home: Dock, Yard, Porch

Summerton

"Kitchen was great, bedooms accomodating. Love the porch!"

Cottage

Prosperity Vacation Rental ~ 1 Mi to Lake Murray!

Hollands Landing

"The property had a lot of land. It was a peaceful, beautiful scenery. They had games in the house, ax throwing, corn hole outside & bonfire. Seeing the neighbors horses walk by was amazing. "

Cottage

Private Boat Dock: Waterfront Lake Murray Haven

Newberry Shores

"Beautiful home! Would stay here again."

Cottage

Pet-friendly Ehrhardt Home w/ Private Pond & Yard!

Ehrhardt

"The property is beautiful. The supplies for smores was a great surprise. Great pet friendly stay. "

Apartment

Steps to Lake Greenwood: Waterfront Gem w/ Patio

Greenwood

"Me and my family really enjoyed the property the view. Everything was nice. We really enjoyed it. Hopefully, we’ll be coming back soon."

See all holiday rentals

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular South Carolina Midlands attractions

A cityscape at dusk with illuminated buildings, a prominent dome structure, and a well-lit street.

University of South Carolina

9.0/10 (2,467 reviews)

Explore the campus of University of South Carolina, a top university in Columbia. Experience the area's acclaimed theatre scene or attend a sporting event.

See properties

Learn more about South Carolina Midlands

Gourmet restaurants, a university vibe and top sights from Fort Jackson to Carowinds Theme Park—discover South Carolina Midlands, a destination also famous for its shopping.

See all hotels in South Carolina Midlands

Top South Carolina Midlands Hotel Reviews

Country Inn & Suites by Radisson, Columbia, SC

10/10 Excellent

"It was very comfortable and clean. Staff was very pleasant and helpful. Swimming pool was amazing and warm. I would stay there again."

Springhill Suites by Marriott Columbia near Fort Jackson

8/10 Good

"We had a great stay at this hotel. The room was spacious, clean, and very comfortable for our large family. The hotel itself was clean, well maintained, and had more modern, updated features than many other hotels we've stayed at. The staff was friendly and helpful, quickly providing extra linens when we requested them. The breakfast area was spacious, well stocked throughout the morning, and offered a nice variety of food choices. Overall, this hotel was a great fit for our family, and we would definitely stay here again."