Find hotels in Southeast Missouri, MO from 1.657.737 ₫
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29 Aug - 30 AugTomorrow
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11 Sep - 13 SepOur top choices for Southeast Missouri hotels
1. Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
Kristen
2.529.566 ₫
2.895.721 ₫ total
includes taxes & fees
3 Sept - 4 Sept
2. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
Matthew
2.607.539 ₫
2.941.668 ₫ total
includes taxes & fees
3 Sept - 4 Sept
3. Perryville RV Resort
Perryville RV ResortPerryville
Von
1.731.579 ₫
1.982.226 ₫ total
includes taxes & fees
30 Aug - 31 Aug
4. Super 8 by Wyndham Potosi
Super 8 by Wyndham PotosiPotosi
Ross
1.518.261 ₫
1.658.321 ₫ total
includes taxes & fees
3 Sept - 4 Sept
5. Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
Allen
2.633.878 ₫
2.982.209 ₫ total
includes taxes & fees
13 Sept - 14 Sept
6. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
Shawn
2.416.127 ₫
2.614.854 ₫ total
includes taxes & fees
30 Aug - 31 Aug
7. The Riverview
The RiverviewCape Girardeau
Alyssa
2.980.715 ₫
3.362.497 ₫ total
includes taxes & fees
31 Aug - 1 Sept
8. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
Jamie
2.216.369 ₫
2.343.257 ₫ total
includes taxes & fees
22 Sept - 23 Sept
9. Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature CollectionFarmington
Susan
2.527.219 ₫
2.750.878 ₫ total
includes taxes & fees
30 Aug - 31 Aug
10. Madison Inn Lodge
Madison Inn LodgeFredericktown
Melissa
2.282.086 ₫
2.492.796 ₫ total
includes taxes & fees
8 Sept - 9 Sept
11. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
ELAINE
2.581.722 ₫
2.912.545 ₫ total
includes taxes & fees
27 Sept - 28 Sept
12. Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
JOAQUIN
2.581.722 ₫
2.798.896 ₫ total
includes taxes & fees
30 Aug - 31 Aug
13. Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
Taylor
3.262.358 ₫
3.696.709 ₫ total
includes taxes & fees
13 Sept - 14 Sept
14. Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
Raidas
1.877.355 ₫
2.117.919 ₫ total
includes taxes & fees
6 Sept - 7 Sept
15. Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
Arsenia
2.637.790 ₫
2.980.043 ₫ total
includes taxes & fees
7 Sept - 8 Sept
16. Super 8 by Wyndham Perryville
Super 8 by Wyndham PerryvillePerryville
Elizabeth
1.773.304 ₫
2.029.991 ₫ total
includes taxes & fees
15 Sept - 16 Sept
17. Black River Motel and Restaurant
Black River Motel and RestaurantLesterville
Douglas
3.027.656 ₫
3.200.989 ₫ total
includes taxes & fees
30 Aug - 31 Aug
18. Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
Sally
2.451.071 ₫
2.818.120 ₫ total
includes taxes & fees
14 Sept - 15 Sept
19. The Farmstead Hotel
The Farmstead HotelCaruthersville
Mary
2.477.410 ₫
2.817.434 ₫ total
includes taxes & fees
30 Aug - 31 Aug
20. Shepherd Mountain Inn
Shepherd Mountain InnIronton
Katie
3.215.417 ₫
3.512.185 ₫ total
includes taxes & fees
31 Aug - 1 Sept
Holiday Rentals in Southeast Missouri
Cabin
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
"I really enjoyed my time at the stay !"
Holiday Home
Tiny Houses of French Village
Tiny Houses of French VillageFrench Village
"Very nice place very clean well kept inside an out it's a nice little romantic getaway they have it set up so great its a must see sunset very relaxing "
Aparthotel
The Atrium - A Boutique Hotel
The Atrium - A Boutique HotelPerryville
"What an amazing little suite wrapped in a very thought-filled overall venue. Very unique room with a so many details. The overall building with fire pit, game rooms, and local vendor items…all was quite amazing. Every element is thought out very well. It is very convenient and overall comfortable. It was a great getaway."
Cottage
Walk to Current River: Ozarks Adventure Home!
Walk to Current River: Ozarks Adventure Home!Van Buren
"Teresa & Chuck went out of their way to make the stay EXCELENT. Teresa is a great cook and shared some of her creations with me, again EXCELENT. The lodging was comfortable and easy to access. Next time in town that will be the place for me."
Cottage
Cozy Belgrade Cottage w/ Wood-burning Stove!
Cozy Belgrade Cottage w/ Wood-burning Stove!Belgrade
Cottage
Cottage w/ Yard, Walk to Historic Attractions
Cottage w/ Yard, Walk to Historic AttractionsSte Genevieve
"The little blue cottage was very comfortable, clean and close to everything downtown. We parked the car and walked everywhere. It was on a quiet street. The bed was comfy, clean kitchen. We liked the little back yard, for relaxing. "
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Stay near popular Southeast Missouri attractions
Photo by Pat Long
Elephant Rocks State Park
9.6/10 (98 reviews)
You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.
Southeast Missouri State University
8.8/10 (248 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
Photo by JG Morris
Lake Wappapello
8.8/10 (54 reviews)
Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.
Century Casino & Hotel Cape Girardeau
8.4/10 (176 reviews)
Why not roll the dice with a visit to Century Casino & Hotel Cape Girardeau during your time in Cape Girardeau? While in this family-friendly area, you can savour the top-notch restaurants.
Century Casino Caruthersville
7.0/10 (57 reviews)
Why not try your luck with a visit to Century Casino Caruthersville during your visit to Caruthersville? While in this family-friendly area, you can enjoy the restaurants.
Learn more about Southeast Missouri
Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to K Bridge Recreation Area.
See all hotels in Southeast Missouri
Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews
Holiday Inn Poplar Bluff by IHG
8/10 Good
"Over all we had a great stay, elevators need some work. Restaurant attached to the hotel was amazing great service and food!!"
Drury Inn & Suites Sikeston, MO
10/10 Excellent
"Everything was great. Very clean"
Drury Inn & Suites Poplar Bluff
10/10 Excellent
"The check-in was quick and friendly. The room was like new. Normal items for hot full breakfast. Check out was quick and friendly. Plenty of parking, easy access, and well lit."
Pear Tree Inn Cape Girardeau West
10/10 Excellent
"Room and Public areas were all immaculate. Check-in was easy and quick."
Honeysuckle Inn - Mountain View
10/10 Excellent
"We only stayed for one night. We basically just slept there and it was very clean and nice for what we needed it for. But if you were to shower there you definitely need your own hygiene products because they just had one set of the tiny bottles so not enough for 2 people. Other then that it was pretty decent as far as road side hotels go."
Baymont by Wyndham Festus
8/10 Good
"Breakfast was good for the cost of room. Very friendly"
Candlewood Suites Cape Girardeau by IHG
10/10 Excellent
"Wonderful stay. Clean, quiet, friendly staff. Will choose Candlewood again."
Fairfield Inn & Suites by Marriott Poplar Bluff
10/10 Excellent
"loved it!!!"
Days Inn and Suites by Wyndham Sikeston
10/10 Excellent
"We stay here every time we are in Sikesons. Can't beat this hotel. Super clean 'comfortable!' beds, living room area, and bathrooms. Small hot breakfast. All for the best price out there. Don't skip on this hotel! Staff is always polite and helpful. We always love to walk out to the pond"
More cheap stays in Southeast Missouri
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
1.522.955 ₫
1.657.737 ₫ total
13 Sept - 14 Sept
includes taxes & fees
Comfort Inn Festus - St Louis South
1303 Veterans Blvd Festus MO
1.578.241 ₫
1.844.175 ₫ total
20 Sept - 21 Sept
includes taxes & fees
7.8/10 Good! (994 reviews)
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
1.729.232 ₫
1.970.892 ₫ total
1 Sept - 2 Sept
includes taxes & fees
Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
2.060.162 ₫
2.307.121 ₫ total
30 Aug - 31 Aug
includes taxes & fees
8/10 Very good! (1,000 reviews)
The Farmstead Hotel
778 E 3rd St Caruthersville MO
2.477.410 ₫
2.817.434 ₫ total
30 Aug - 31 Aug
includes taxes & fees
8.6/10 Excellent! (602 reviews)
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street Cape Girardeau MO
2.581.722 ₫
2.912.545 ₫ total
27 Sept - 28 Sept
includes taxes & fees
Hotels in Southeast Missouri with star rating
4 Star Hotels
2 properties
3 Star Hotels
70 properties
