The Best Hotels Closest to St. Louis Science Center in St. Louis - 2026 Updated Prices

A space shuttle exhibit with a large model of a space shuttle, a red pillar, and informational displays.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for St. Louis Science Center hotels

A swimming pool with a 40 ft depth marker, lounge chairs, and a brick wall.

A hotel room with two beds, a chair, a lamp, and a heater.

A Drury Inn & Suites building with a brick facade, multiple windows, and a parking lot with several cars.

1. Drury Inn & Suites St. Louis Forest Park

2 km from St. Louis Science Center

Tammy

3.494.216 ₫

4.085.751 ₫ total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

A hotel reception area with a modern design, featuring a reception desk, a wall with a welcome sign, and a view of the lobby.

A spacious room with a long table and chairs, a television mounted on the wall, and a 'Welcome to the Show Nest' sign.

A snack and treat display with various products, including chips and beverages, in a store setting.

2. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 1 km from St. Louis Science Center

Melissa

3.587.143 ₫

4.230.283 ₫ total

includes taxes & fees

11 Nov - 12 Nov

A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

A restaurant with multiple dining tables and chairs, a bar area with shelves of bottles, and a large mirror above the bar.

An outdoor patio with a brick fireplace, wicker furniture, and a dining table set with food and drinks.

A bar area with a marble counter, bar stools, and a variety of liquor bottles.

3. The Royal Sonesta Chase Park Plaza St. Louis

Central West End, 1.8 km from St. Louis Science Center

Kristina

4.167.485 ₫

5.677.763 ₫ total

includes taxes & fees

15 Nov - 16 Nov

A modern living room with a fireplace, sofas, a coffee table, and a bookshelf.

A modern living room with a fireplace, comfortable seating, and a large TV.

A modern hotel lobby with a marble reception desk, a bar area, and a seating space.

A hotel with a modern facade, large windows, and a sign reading "AC HOTEL CENTRAL WEST END".

4. AC Hotel St. Louis Central West End

Central West End, 1.8 km from St. Louis Science Center

Jeffrey

3.938.403 ₫

4.644.518 ₫ total

includes taxes & fees

15 Nov - 16 Nov

An outdoor patio area with seating, planters, and a grill.

A building with a sign that reads "element by Westin" on a brick wall.

A spacious lobby with a modern design, featuring a seating area with sofas and armchairs, a reception desk, and a large window providing a view of the interior.

A modern bar area with a long counter, bar stools, and a variety of bottles.

5. Element by Marriott St. Louis Midtown

Midtown, 2.7 km from St. Louis Science Center

Desirae

3.416.820 ₫

3.995.254 ₫ total

includes taxes & fees

22 Oct - 23 Oct

An outdoor dining area with multiple wooden tables and benches, surrounded by wicker chairs.

A hotel with a covered outdoor seating area, a parking lot, and a sign for a restaurant.

A group of people sitting on a couch in a well-lit room with a large plant and a floor lamp.

A modern cafe interior with a bar area, seating, and a menu board.

6. Hotel Indigo St Louis - Central West End by IHG

Central West End, 1.7 km from St. Louis Science Center

Lydia

3.235.625 ₫

4.099.698 ₫ total

includes taxes & fees

15 Nov - 16 Nov

A hot tub with a wooden deck, surrounded by a bamboo fence, and string lights.

A reception area with a Christmas tree, a neon sign, and a Santa Claus figure.

A building with a brick facade, a covered entrance, and a tree adorned with string lights.

A spacious lobby with grey sofas, wooden coffee tables, and potted plants.

7. The West End

Central West End, 2.3 km from St. Louis Science Center

Trevor

2.551.199 ₫

3.500.791 ₫ total

includes taxes & fees

19 Oct - 20 Oct

An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

A compact kitchen with a stainless steel microwave, a sink, and a coffee maker.

A modern indoor seating area with a sofa, tables, and chairs.

A hotel room with a bed, a pink sofa, a small table, and a chair. There is a window with a view of a building.

8. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 0.9 km from St. Louis Science Center

paullita jeanne

4.024.600 ₫

4.705.924 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A pool area with clear water, red lounge chairs, and a view of the outside through large windows.

A snack bar with various packaged snacks and a menu display.

A modern hotel with a prominent 'aloft' sign, a 'WXYZ' sign, and a 'Coming Soon' advertisement on the side.

A gym with exercise equipment, a mirrored wall, and a patterned carpet.

9. Aloft by Marriott St Louis Central West End

Central West End, 1.8 km from St. Louis Science Center

Brittany

2.948.302 ₫

3.447.420 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A modern hotel room with a large bed, a desk with a chair, a blue armchair, a sofa, a TV, and a large window offering a city view.

A modern kitchen with wooden cabinets, a central island, and a wall display of packaged goods.

A hotel room with a sofa, a blue armchair, a desk with a computer, a TV, and a bed.

A spacious lobby with leather sofas, a patterned rug, and a reception desk.

10. DoubleTree by Hilton St. Louis Forest Park

Central West End, 1.3 km from St. Louis Science Center

Loleta

3.849.617 ₫

4.539.815 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A spacious foyer with a grand staircase, a piano, and a large rug.

A hallway with wooden doors, a wall-mounted tree decoration, a small table with a plant, and a painting.

A spacious dining area with a round glass table, black metal chairs, and a wooden staircase leading to an upper level.

A backyard with a stone fire pit, two Adirondack chairs, and a hammock.

11. White House at Grand Central

3 km from St. Louis Science Center

Mark

1.969.421 ₫

3.208.800 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A bedroom with a large bed, a mirror, and a vanity with shelves.

A wall with a large, abstract mirror design.

A room with a grand piano, a round table with a red and white tablecloth, and a statue of a robed figure.

A modern bedroom with a large bed, a sitting area with a sofa and chairs, a vanity with a mirror, and a ceiling fan.

12. Central West End B&B

Central West End, 3 km from St. Louis Science Center

Stacee

4.261.448 ₫

5.361.207 ₫ total

includes taxes & fees

19 Oct - 20 Oct

A hotel room with two beds, a chair, a desk, and a large window.

A conference room with a floral carpet, tables with chairs, and a large orange pendant light.

A reception desk with a sign reading "Forest Park Hotel" and a clock on the wall.

A bathroom with a bathtub, toilet, and sink.

13. Forest Park Hotel by MDR

The Hill, 1.8 km from St. Louis Science Center

Kevan

1.998.840 ₫

2.457.988 ₫ total

includes taxes & fees

15 Nov - 16 Nov

A hotel room with a desk, a television, a bed, a mirror, and a coffee maker.

A reception area with a counter, a clock, and a sign indicating free Wi-Fi availability.

A wooden surface with a metal rod and a power outlet with a red plug-in sign.

A Red Roof Plus hotel with a stone facade, a parking lot, and a covered outdoor area.

14. Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

The Hill, 1.8 km from St. Louis Science Center

Sean

1.942.423 ₫

2.271.256 ₫ total

includes taxes & fees

21 Oct - 22 Oct

A room with a green armchair, a round table, a lamp, and a mirror on the wall.

A room with a bed, a nightstand with a lamp, a painting on the wall, and a radiator.

A two-story building with a dark entrance, large windows, and a brick facade.

A modern interior with a staircase, a large abstract painting, and a seating area with a glass coffee table.

15. Truitt Hotel

Lafayette Square, 4.9 km from St. Louis Science Center

Gabrielle

4.348.680 ₫

5.278.987 ₫ total

includes taxes & fees

19 Oct - 20 Oct

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.

A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.

An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

16. Drury Plaza Hotel St. Louis Brentwood

6.5 km from St. Louis Science Center

Janell

3.313.021 ₫

3.934.852 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A rooftop terrace with wicker furniture, offering a city view.

A hotel room with a large window offering a view of the Gateway Arch and a modern building.

A lobby with seating areas, a chandelier, and a large pillar.

A modern hotel lobby with a bar area, seating arrangements, and a large chandelier.

17. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis, 7.1 km from St. Louis Science Center

Theresa

3.494.216 ₫

4.085.751 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A hotel room with a bed, a desk, a television, and a lamp.

A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.

A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.

18. Pear Tree Inn St. Louis Airport

15 km from St. Louis Science Center

Murphy

2.329.391 ₫

2.765.872 ₫ total

includes taxes & fees

22 Oct - 23 Oct

A modern hotel lobby with a glass facade, seating area, and a staircase.

A couple relaxing by a window overlooking a bridge and water.

A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.

A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.

19. Four Seasons Hotel St Louis

7.5 km from St. Louis Science Center

Nicole

9.706.875 ₫

11.350.055 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

A modern bar area with a central fire feature, bar stools, and seating.

The exterior of the Clark & Bourbon hotel with a well-lit entrance, a marquee sign, and a landscaped planter area.

A modern living room with a sofa, coffee table, and bookshelves.

20. Live by Loews - St.Louis

Downtown St. Louis, 6.7 km from St. Louis Science Center

Molly

3.598.015 ₫

4.279.083 ₫ total

includes taxes & fees

15 Nov - 16 Nov

View all properties

Compare popular hotels close to St. Louis Science Center

Property	Property class	Guest rating
Drury Inn & Suites St. Louis Forest Park	9.4 Exceptional 1,027 reviews	View
Hampton Inn & Suites St. Louis at Forest Park	9.4 Exceptional 1,002 reviews	View
The Royal Sonesta Chase Park Plaza St. Louis	9.2 Wonderful 1,004 reviews	View
AC Hotel St. Louis Central West End	9.0 Wonderful 857 reviews	View
Element by Marriott St. Louis Midtown	8.8 Excellent 843 reviews	View

Top St. Louis Science Center Hotel Reviews

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

8/10 Good

"Pretty cool hotel"

Drury Inn & Suites St. Louis Forest Park

10/10 Excellent

"The outside/inside pool and inside hot tub was great for the family! The included breakfast and dinner/drinks, free parking and free WiFi far outweighed the drive to and from downtown St Louis and the view we could have had. The staff was so sweet and accommodating. The hotel was one of the best parts of our trip!"

Hotel Indigo St Louis - Central West End by IHG

10/10 Excellent

"One of my favorite hotels to stay at when I come to the Lou."

Moonrise Hotel

10/10 Excellent

"Had the Vincent Price suite with a city view. Also loved the rooftop terrace."

Forest Park Hotel by MDR

10/10 Excellent

"Great, great, great property. well restored, you know, rung back. You tell us it’s buildings older. Amenities are great. Staff’s great, clean. go above and beyond to try to be helpful as much as they can. I felt safe. Yeah, all around good property"

Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

10/10 Excellent

"Staff was"

DoubleTree by Hilton St. Louis Forest Park

10/10 Excellent

"Room was very clean. Staff helpful. Great air conditioning. Vent does not blow directly at bed. Most hotels do and it is nice not having it blow directly onto you. Convenient parking. Great place to stay especially when you have testing at the Center for Advanced Medicine. Skywalk connects hotel to all hospital areas. Great experience once again. Have stayed at this Doubletree several times. My go to hotel in St. Louis."

Other attractions near St. Louis Science Center

A modern building with large glass windows and a garden with red and pink tulips.

Jewel Box

Explore the great outdoors at Jewel Box, a lovely green space in St. Louis. Amble around the area's lush forest or attend a sporting event.

See properties

A stone fountain with water cascading down a tiered structure, surrounded by a pond and a grassy area with a building in the background.

Forest Park

9.2/10 (3,389 reviews)

After visiting Forest Park, make a plan to see the other sights and activities in St. Louis. Discover the area's entertainment choices and shops.

See properties

A gazebo with columns and a dome roof, surrounded by a pond and greenery.

Pagoda Circle

You can spend an afternoon studying the exhibits at Pagoda Circle during your trip to St. Louis. Experience the area's fascinating museums or attend a sporting event.

See properties

A theater stage with a variety of neon signs advertising different businesses.

The Muny Theater

8.6/10 (7 reviews)

You can get tickets for a performance at The Muny Theater during your trip to St. Louis. Amble around the area's lush forest or attend a sporting event.

See properties

Highlands Golf & Tennis Center

Catch an event at Highlands Golf & Tennis Center during your trip to St. Louis. Experience the area's entertainment choices or attend a baseball game.

See properties

Atomic Cowboy

Atomic Cowboy is just one of the places to see in St. Louis, so why not enjoy the other things to explore during your travels?

See properties

Atomic by Jamo

Atomic by Jamo is just one of the places to see in St. Louis, so why not enjoy the other things to explore during your travels?

See properties

Frequently asked questions

What's the area like around St. Louis Science Center?

St. Louis Science Center is located in a welcoming area of St. Louis known for its picturesque gardens and sporting events. If you're looking for a convenient place to stay, take a look at the 74 hotels and other accommodation options you'll find within a mile.

How many hotels should I expect to find close to St. Louis Science Center?

Expedia has 74 hotels and other accommodation options within a mile from St. Louis Science Center.

If I need to cancel the hotel reservation for my stay near St. Louis Science Center, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals near St. Louis Science Center.

What can I see and do near St. Louis Science Center?

Cathedral Basilica of St. Louis, St. Louis Art Museum and City Museum feature captivating exhibits. St. Louis Union Station, Jewel Box and Cherokee Street are monuments to see when you're exploring the area around St. Louis Science Center. You can check out the local talent at The Muny Theater, Fox Theater and St. Louis Symphony Orchestra.

Search Hotels Near St. Louis Science Center, St. Louis

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for St. Louis Science Center hotels

1. Drury Inn & Suites St. Louis Forest Park

2. Hampton Inn & Suites St. Louis at Forest Park

3. The Royal Sonesta Chase Park Plaza St. Louis

4. AC Hotel St. Louis Central West End

5. Element by Marriott St. Louis Midtown

6. Hotel Indigo St Louis - Central West End by IHG

7. The West End

8. Home2 Suites by Hilton St. Louis/Forest Park

9. Aloft by Marriott St Louis Central West End

10. DoubleTree by Hilton St. Louis Forest Park

11. White House at Grand Central

12. Central West End B&B

13. Forest Park Hotel by MDR

14. Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

15. Truitt Hotel

16. Drury Plaza Hotel St. Louis Brentwood

17. Drury Plaza Hotel St. Louis at the Arch

18. Pear Tree Inn St. Louis Airport

19. Four Seasons Hotel St Louis

20. Live by Loews - St.Louis

Compare popular hotels close to St. Louis Science Center

Top St. Louis Science Center Hotel Reviews

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Drury Inn & Suites St. Louis Forest Park

Hotel Indigo St Louis - Central West End by IHG

Moonrise Hotel

Forest Park Hotel by MDR

Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

DoubleTree by Hilton St. Louis Forest Park

Other attractions near St. Louis Science Center

Jewel Box

Forest Park

Pagoda Circle

The Muny Theater

Highlands Golf & Tennis Center

Atomic Cowboy

Atomic by Jamo

Frequently asked questions