Photo by Alice Burghart
Compare and book 2 Star hotels in Cape Girardeau, Missouri
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Our top choices for Cape Girardeau 2-star hotels
9.0 out of 10, Wonderful, (1000)
"Great stay"
Heather
The price is 1.842.417 ₫
2.078.543 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1000)
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
Brian
The price is 2.500.780 ₫
2.821.230 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical CenterCape Girardeau
9.0 out of 10, Wonderful, (1001)
"Nice place for a stay at a reasonable price."
Arthur
The price is 1.842.417 ₫
2.078.543 ₫ total
includes taxes & fees
24 Dec - 25 Dec
8.2 out of 10, Very good, (882)
"Room was clean and spacious."
George
The price is 2.026.948 ₫
2.431.462 ₫ total
includes taxes & fees
19 Jan - 20 Jan 2026
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (140)
"Nice hotel, clean and comfortable "
Laura
The price is 2.316.512 ₫
2.613.350 ₫ total
includes taxes & fees
28 Dec - 29 Dec
9.6 out of 10, Exceptional, (102)
"It was a nice stay"
Douglas
The price is 2.352.839 ₫
2.677.860 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
7.2 out of 10, Good, (685)
"Overall was wonderful customer service and breakfast"
Stephanie
The price is 1.516.262 ₫
1.710.555 ₫ total
includes taxes & fees
28 Dec - 29 Dec
9.6 out of 10, Exceptional, (785)
"Excellent stay"
Christina
The price is 2.676.624 ₫
3.019.606 ₫ total
includes taxes & fees
26 Dec - 27 Dec
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Explore similar 3-star hotels
Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Cape Girardeau.
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
The price is 2.368.897 ₫ per night from 23 Dec to 24 Dec
2.368.897 ₫
2.672.149 ₫ total
23 Dec - 24 Dec
includes taxes & fees
9.4/10 Exceptional! (1,004 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Cape Girardeau
Explore the mighty Mississippi from the riverfront park where historic murals tell stories of river life. Climb to the top of Academic Hall at Southeast Missouri State or hunt for antiques along downtown's brick-paved streets.
Photo by Alice Burghart
Open Photo by Alice Burghart