Photo by Alice Burghart

Compare and book 4 Star hotels in Cape Girardeau, Missouri

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Cape Girardeau 4 Star Hotels

Tonight
21 Dec - 22 Dec
Tomorrow
22 Dec - 23 Dec
Next weekend
26 Dec - 28 Dec
In two weeks
2 Jan - 4 Jan

Our top choices for Cape Girardeau 4-star hotels

Lobby sitting area
The Riverview

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (474)
"The room was clean and the mattress was extremely comfortable "
United States
Stacy
The price is 2.534.134 ₫
2.858.859 ₫ total
includes taxes & fees
22 Dec - 23 Dec
The Riverview
Honeymoon Suite, 1 King Bed, Non Smoking, Courtyard View | View from room
Davie School Inn

Davie School Inn

Davie School Inn
4.0 star property
Anna
10.0 out of 10, Exceptional, (51)
"very friendly hosts, great bfasts, excellent stay!"
United States
Rebecca
Davie School Inn
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Cape Girardeau

Explore the mighty Mississippi from the riverfront park where historic murals tell stories of river life. Climb to the top of Academic Hall at Southeast Missouri State or hunt for antiques along downtown's brick-paved streets.

See all hotels in Cape Girardeau
Beautiful city by the Mississippi River
Photo by Alice Burghart
Open Photo by Alice Burghart

Top Cape Girardeau Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Cape Girardeau?
Expedia can help you easily locate the ideal 4-star hotel for your trip to Cape Girardeau. Use our handy filter tool to fine-tune your search by things like price, amenities and star rating and get access to fabulous deals in a couple of clicks.

  • Search for the lowest price from 2.858.859 ₫

What's the difference between 5-star and 4-star hotels in Cape Girardeau?
Offering a welcoming traveller experience and upscale décor, 4-star hotels are a great option for your Cape Girardeau holiday. These kinds of accommodation generally feature loads of useful amenities that make it a breeze to unpack and recharge — think complimentary bathrobes, restaurants and pools. Or live the high life at a 5-star hotel designed to spoil you with luxury perks and amenities. 24-hour front desk, oversized bathrooms and world-class dining are typically included at these plush properties.
Does Cape Girardeau have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to find your next getaway in Cape Girardeau where everything is taken care of, from your room to your food, activities and entertainment. We can also help you find standard 4-star stays in and around this popular destination.