Compare and book 4 Star hotels in Downtown Santiago, Santiago
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Downtown Santiago 4 Star Hotels
Our top choices for Downtown Santiago 4-star hotels
8.2 out of 10, Very good, (614)
"The hotel is located at the prime spot, great place to do shopping and good restaurants around. "
Sivasankar
The price is 2.108.560 ₫
2.108.560 ₫ total
13 Dec - 14 Dec
8.4 out of 10, Very good, (540)
"Kudos to Hotel Meridien for having Ms Ana Echeverria and Mr John Freire. They are helpful, friendly and accommodating. A pleasure to stay here. The room is immaculate, food delicious. The Hotel close to Metro yet quiet, safe area."
GILBERT MENDOZA
The price is 2.237.965 ₫
2.237.965 ₫ total
20 Dec - 21 Dec
9.2 out of 10, Wonderful, (969)
"Location beautiful hotel lovely friendly staff
Close to everything "
stan
The price is 3.893.269 ₫
3.893.269 ₫ total
20 Dec - 21 Dec
9.0 out of 10, Wonderful, (683)
"Friendly and helpful staff. Food at the rooftop restaurant was delicious!!"
Chantal
The price is 3.327.986 ₫
3.327.986 ₫ total
11 Jan - 12 Jan 2026
9.6 out of 10, Exceptional, (913)
"Great hotel in good location. "
Catharine
The price is 4.739.220 ₫
4.739.220 ₫ total
11 Jan - 12 Jan 2026
9.6 out of 10, Exceptional, (313)
"Great location, lovely staff, good breakfast! "
james
The price is 8.767.557 ₫
8.767.557 ₫ total
24 Dec - 25 Dec
8.6 out of 10, Excellent, (259)
"Very friendly staff, excellent location. Continental breakfast was very filling and restaurant food was very good."
Glen C
9.2 out of 10, Wonderful, (510)
"The staff were all so incredibly nice!!! The hotel was beautiful too!!"
Kimberly
The price is 3.649.199 ₫
3.649.199 ₫ total
22 Dec - 23 Dec
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 5-star hotels
Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Downtown Santiago.
The Singular Santiago
Merced 294 Santiago Region Metropolitana
The price is 6.187.315 ₫ per night from 24 Dec to 25 Dec
6.187.315 ₫
6.187.315 ₫ total
24 Dec - 25 Dec
9.4/10 Exceptional! (675 reviews)
Still don't see what you're looking for?
See all properties in Downtown Santiago.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Downtown Santiago Hotel Reviews
Explore a world of travel with Expedia
Hotels in Downtown Santiago by Star Rating
Accommodation near Downtown Santiago attractions
- Hotels near Palacio de la Moneda
- Hotels near Plaza de Armas
- Hotels near Fantasilandia
- Hotels near Lastarria District
- Hotels near Mercado Central
- Hotels near Santiago Town Square
- Hotels near O'Higgins Park
- Hotels near Movistar Arena
- Hotels near Museum of Memory and Human Rights
- Hotels near Barrio París-Londres
- Hotels near Municipal Theatre of Santiago
- Hotels near Pontifical Catholic University of Chile
- Hotels near Catholic University Clinical Hospital
- Hotels near Metropolitan Cathedral
- Hotels near San Francisco Church
- Hotels near National Museum of Natural History
- Hotels near National Museum of Fine Arts
- Hotels near Plaza de la Constitucion
Choose Your Downtown Santiago Hotel Style
- Beach Resorts & Hotels in Downtown Santiago
- Boutique Hotels in Downtown Santiago
- Business Hotels in Downtown Santiago
- Historic Hotels in Downtown Santiago
- Hotels with Air Conditioning in Downtown Santiago
- Hotels with Airport Transfers in Downtown Santiago
- Hotels with Balcony in Downtown Santiago
- Hotels with Gym in Downtown Santiago
- Hotels with Indoor Pools in Downtown Santiago
- Hotels with Parking in Downtown Santiago
- Hotels with Pool in Downtown Santiago
- Hotels with Restaurant in Downtown Santiago
- Hotels with Wifi in Downtown Santiago
- Hotels with a Bar in Downtown Santiago
- Hotels with a View in Downtown Santiago
- Luxury Hotels in Downtown Santiago
- Pet-Friendly Hotels in Downtown Santiago
- Shopping Hotels in Downtown Santiago
- Ski Hotels in Downtown Santiago
- Wedding Hotels in Downtown Santiago
- Winery Hotels in Downtown Santiago
Recommended cities for you
Explore more hotels
Expedia's Latest Trends
Hotels
Flights
Packages