A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

Compare and book 4 Star hotels in Panama City, Panamá Province

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Check availability on Panama City 4 Star Hotels

Tonight
8 Oct - 9 Oct
Tomorrow
9 Oct - 10 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Panama City 4-star hotels

A spacious lobby with a high ceiling, modern lighting fixtures, and a glass entrance leading to a lower level.
A modern bar area with a central island, bar stools, and a television mounted on the ceiling.
A modern dining area with a wooden table and chairs, a built-in bookshelf, and a decorative hanging light fixture.
A swimming pool with a clear water surface, surrounded by a covered area with lounge chairs and a bar area.

1. Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
Tocumen Airport
United States
Duran
3.481.320 ₫
4.000.920 ₫ total
includes taxes & fees
6 Nov - 7 Nov
Crowne Plaza Panama Airport by IHG
A multi-story building with balconies, arched windows, and decorative railings.
A building with a balcony and a street view.
A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.
A multi-level atrium with wooden staircases, seating areas, and a decorative ceiling.

2. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
Casco Viejo
United States
Olga
4.764.732 ₫
5.241.205 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Central Hotel Panama Casco Viejo
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
A rooftop lounge with modern seating and a panoramic city view.
A modern spa area with a hot tub, seating, and a city view.
An escalator in a hotel lobby with a patterned wall and framed artwork.

3. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
benjamin
4.245.575 ₫
4.670.132 ₫ total
includes taxes & fees
31 Oct - 1 Nov
Megapolis Hotel Panamá
Pool
A balcony with a view of a swimming pool, palm trees, and city buildings.
A buffet area with a variety of dishes, a long counter with food, and a seating area with tables and chairs.
A reception area with marble reception desks and a sign indicating the reception desk.

4. Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Bella Vista
United States
Althea
2.760.375 ₫
3.036.413 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
A balcony with wicker chairs and a view of the cityscape.
A rooftop pool area with a view of high-rise buildings in the background.
A reception area with a marble wall, a 'Free Wireless Internet' sign, and a floral arrangement.
A multi-story hotel with a modern facade, large windows, and a prominent entrance with a covered area.

5. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
San Francisco
United States
Luis
2.607.198 ₫
2.867.918 ₫ total
includes taxes & fees
11 Oct - 12 Oct
Ramada Plaza by Wyndham Panama Punta Pacifica
A resort with a large swimming pool, thatched-roof structures, and palm trees.
A hotel room with a large bed, a chair, a desk, and a view of the ocean.
A resort with a pool, palm trees, and a building with a red roof.
A well-maintained garden with a pathway leading to a gazebo, surrounded by palm trees and a view of the sea.

6. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
Veracruz
United States
Babak
7.230.234 ₫
7.230.234 ₫ total
includes taxes & fees
9 Oct - 10 Oct
Dreams Playa Bonita Panama - All Inclusive
A modern living room with a sofa, a coffee table, a flat-screen TV, and a view of greenery through large windows.
A hotel room with two beds, a desk, a television, and an air conditioning unit.
A playground with multiple slides and climbing structures.
A conference room with a long table, chairs, and a carpeted floor.

7. Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
Tocumen Airport
United States
Lucas
2.812.630 ₫
3.093.893 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Riande Aeropuerto Hotel & Casino
A modern building with a glass facade, a curved structure, and a flat roof.
A modern hotel room with a large bed, a TV, a desk, and a view of the city.
A modern hotel room with a large bed, a desk with a flat-screen TV, a city view, and a large painting on the wall.
A rooftop lounge area with clear glass tables and chairs, a pool, and potted plants.

8. Decapolis Hotel Panama City

Decapolis Hotel Panama City
San Francisco
United States
Jorge Luis
2.259.716 ₫
2.485.688 ₫ total
includes taxes & fees
31 Oct - 1 Nov
Decapolis Hotel Panama City
A buffet with various food items including fruits, juices, and cheeses.
A modern hotel lobby with a sectional sofa, a glass coffee table, and a vibrant green wall mural.
An aerial view of a rectangular swimming pool with two lounge chairs and a ladder.
A hotel reception area with a wooden reception desk, seating area with chairs and ottomans, and a large window providing natural light.

9. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
San Antonio
United States
Chaloma
2.629.176 ₫
2.892.094 ₫ total
includes taxes & fees
30 Oct - 31 Oct
Courtyard by Marriott Panama Metromall
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.
A modern reception area with a wooden panel wall, a sign indicating 'Marriott Bonvoy', and three reception desks with digital displays.
A coastal building complex with multiple structures, a prominent tower, and a beach in the foreground.
A modern lounge area with a wooden partition, a bar with a variety of bottles, and a seating area with chairs.

10. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
San Francisco
United States
SHARROW
2.949.250 ₫
3.244.175 ₫ total
includes taxes & fees
31 Oct - 1 Nov
Courtyard by Marriott Panama Multiplaza Mall
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.
An indoor swimming pool with lounge chairs and a modern interior design.
A modern hotel room with a large window offering a city view, a chandelier, and a cozy seating area.
A modern living area with a sofa, chairs, and a coffee table. There is a view of the city through large windows.

11. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
San Francisco
United States
Armando
3.946.882 ₫
4.341.518 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Las Americas Golden Tower Panama
A rooftop pool area with lounge chairs and a bar, overlooking a city skyline at sunset.
A modern hotel lobby with a glass railing, seating area, and contemporary lighting fixtures.
A spacious lobby with high ceilings, large windows, and modern lighting fixtures.
A rooftop terrace with outdoor seating, potted plants, and a view of a hill with buildings in the distance.

12. Marriott Panama Hotel

Marriott Panama Hotel
Panama City
United States
Calvin
4.624.440 ₫
5.086.884 ₫ total
includes taxes & fees
17 Oct - 18 Oct
Marriott Panama Hotel
A hotel room with a large bed, bedside tables with lamps, a chair, and a large window with curtains.
A hotel room with a sofa, a coffee table, a TV, and a cabinet.
A rooftop swimming pool with lounge chairs and a city skyline in the background.
A cityscape with modern high-rise buildings, including a prominent tower labeled 'TOWERBANK.'

13. Studio Coliving

Studio Coliving
Bella Vista
United States
Phillip
Studio Coliving
A rooftop pool with sun loungers and a city skyline in the background.
A long, narrow hallway with a wooden floor and light-colored walls.
A bar area with a curved counter, multiple screens, and a patterned carpet.
A spacious lobby with a blue sofa, multiple armchairs, and a coffee table.

14. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
Bella Vista
United States
kevin
2.318.715 ₫
3.979.616 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Waymore Hotel Spa & Casino
A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.
A spacious lobby with large windows, a curved ceiling, and a seating area with a patterned rug.
A hotel room with a bed and a view of a cityscape through sheer curtains.
A bar area with a variety of liquor bottles, a counter, and seating with tables and chairs.

15. Novotel Panama City

Novotel Panama City
Bella Vista
United States
CARLOS
3.039.660 ₫
3.343.626 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Novotel Panama City
A resort with a pool area, lounge chairs, and a view of a bridge at night.
A hotel room with a bed, a TV on a wooden cabinet, a nightstand with a lamp, and a view of the outdoors through a glass door.
A bar area with a counter, stools, and a seating area with tables and chairs.
A reception desk with three staff members, a green patterned wall, a wooden reception area, and a large plant.

16. Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
Amador
United States
Jose
2.045.975 ₫
2.250.469 ₫ total
includes taxes & fees
14 Oct - 15 Oct
Radisson Hotel Panama Canal
A buffet with various food items and a decorative plant.
A spa area with a hot tub, candles, and a curved bench.
A hotel with a swimming pool, outdoor seating, and a modern architectural design.
A spacious lobby with a high ceiling, a glass railing on the upper level, and a seating area with modern furniture.

17. Sheraton Grand Panama

Sheraton Grand Panama
San Francisco
United States
Nicole
4.527.015 ₫
4.979.716 ₫ total
includes taxes & fees
31 Oct - 1 Nov
Sheraton Grand Panama
A poolside area with covered seating and palm trees.
A modern hotel lobby with a glass facade, seating area with loungers, and a wooden floor.
A modern interior with a large abstract sculpture, a staircase, a sofa with orange cushions, and a patterned rug.
A modern reception area with a large window, a geometric patterned floor, and two potted plants.

18. Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Bella Vista
United States
Jahzenia
6.728.820 ₫
7.401.702 ₫ total
includes taxes & fees
12 Oct - 13 Oct
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
A spacious indoor area with high ceilings, large windows, and multiple dining tables.
A multi-story hotel with a central courtyard, balconies, and a view of the city skyline.
A spacious lobby with a tiled floor, large windows, and potted plants.
A restaurant with brick walls, arched windows, and a variety of seating arrangements including tables and chairs.

19. American Trade Hotel

American Trade Hotel
Casco Viejo
United States
Ashleigh-Ann
4.656.915 ₫
5.122.607 ₫ total
includes taxes & fees
15 Oct - 16 Oct
American Trade Hotel
A wooden door with a number plate, a black and white striped bag, and a lantern on the ground.
A rooftop bar with potted plants, seating, and a view of a city skyline.
A restaurant with a wine display and a table set for two.
A bedroom with a large bed, a stone wall, a wooden bench, and a hanging light fixture.

20. Hotel Casa Panamá

Hotel Casa Panamá
Casco Viejo
United States
Naveera Jyoti
1.703.457 ₫
1.873.803 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Hotel Casa Panamá
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Panama City.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama
3.428.016 ₫
3.770.818 ₫ total
21 Oct - 22 Oct
includes taxes & fees
Hotel Riu Plaza Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

47th St. & Uruguay Street Panama City Panama
6.823.647 ₫
7.506.012 ₫ total
31 Oct - 1 Nov
includes taxes & fees
Waldorf Astoria Panama
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

Calle Primera Oeste, San Felipe Panama City Panama
9.118.980 ₫
10.030.878 ₫ total
3 Nov - 4 Nov
includes taxes & fees
Sofitel Legend Casco Viejo, Panama City
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

See all hotels in Panama City
A city skyline with high-rise buildings, a calm waterfront, and a sunset sky.

Top Panama City Hotel Reviews

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

10/10 Excellent
"N/A"
WINIFER TORIBIO 3-night trip
Posted 5 hours ago
Waymore Hotel Spa & Casino
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

8/10 Good
"Good hotel conveniently located in the mall but not directly connected inside it. It’s by the parking lot. My only other complaint is that they don’t have AC or at least don’t turn it on for the hallways and elevators so it can get very hot on your way to the lobby. Otherwise decent hotel, good breakfast and friendly staff."
Luis 3-night trip
Posted 12 hours ago
Courtyard by Marriott Panama Multiplaza Mall
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

8/10 Good
"Great views, great breakfast each morning, friendly staff, central location. The only downfall was climate control, the rooms were very humid causing our room to be musty. They did provide and humidifier which helped. Overall a wonderful experience for our first time in Panama."
Amelia 7-night trip
Posted 15 hours ago
Las Americas Golden Tower Panama
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

8/10 Good
"N/A"
Carlos 1-night trip
Posted 2 days ago
Central Hotel Panama Casco Viejo

Frequently asked questions

What are the best 4-star hotels in Panama City?
Continental Hotel Panamá is a 4-star hotel in Panama City that's popular among Expedia customers. An art gallery and proposal/romance packages are just a couple of its amenities. Travellers also recommend Hotel El Panama by Faranda Grand, a member of Radisson Individuals. From a swimming pool to a steam room, it offers conveniences that cater to every aspect of your relaxation and entertainment.
How much does it cost to stay in a 4-star hotel in Panama City?
To lock in a 4-star hotel in Panama City that fits your budget, make use of Expedia's handy search filters. Take a look at the availability during your holiday dates and use our pricing filter to set your limit. You can also sort your results by the most affordable escape first.
  • Search for the lowest price from 3.770.818 ₫
What's the difference between 5-star and 4-star hotels in Panama City?
Offering a friendly traveller experience and upmarket décor, 4-star hotels are a fantastic option for your Panama City holiday. These types of accommodation generally feature loads of useful amenities that make it a breeze to unpack and unwind — think 24-hour room service, gyms and pools. Or enjoy even more lavishness at a 5-star hotel designed to indulge you in high-end perks and amenities. Concierge assistance, complimentary toiletries and fine dining are typically included at these swanky properties.