Compare and book 4 Star hotels in St. Charles, St. Louis

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on St. Charles 4 Star Hotels

This weekend
Next weekend

Our top choices for St. Charles 4-star hotels

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,073 reviews)
"Everything about this hotel was excellent."
United States
Vivian
The price is 4.132.083 ₫
4.872.963 ₫ total
includes taxes & fees
12 Jun - 13 Jun
Hyatt Regency St. Louis at The Arch

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very good, (1,090 reviews)
"Great location to the airport and staff was very welcoming!"
United States
James
The price is 3.553.065 ₫
4.156.660 ₫ total
includes taxes & fees
28 Jun - 29 Jun
Renaissance St. Louis Airport Hotel

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1,876 reviews)
"Great stay"
United States
Alexander
The price is 4.447.911 ₫
5.332.492 ₫ total
includes taxes & fees
7 Jun - 8 Jun
21C Museum Hotel St Louis

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,201 reviews)
"Really nice hotel. Worth the price because it's right near the ball park and bars."
United States
Aaron
The price is 4.184.721 ₫
4.976.846 ₫ total
includes taxes & fees
21 Jun - 22 Jun
Live by Loews - St.Louis

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1,592 reviews)
"The hotel was very clean and the staff was extremely friendly and accommodating."
United States
Carl
The price is 2.736.966 ₫
3.569.335 ₫ total
includes taxes & fees
4 Jun - 5 Jun
River City Casino & Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,287 reviews)
"The staff is wonderful, helpful, and friendly. Great bar and great location. I would definitely stay here again."
United States
Marlynn
The price is 3.658.341 ₫
4.350.794 ₫ total
includes taxes & fees
28 Jun - 29 Jun
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.0 out of 10, Wonderful, (1,006 reviews)
"Clean rooms, great staff "
United States
Sowmya
The price is 5.132.205 ₫
6.828.242 ₫ total
includes taxes & fees
28 Jun - 29 Jun
The Royal Sonesta Chase Park Plaza St. Louis

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
Frontenac
8.8 out of 10, Excellent, (1,007 reviews)
"Very unique and picturesque hotel"
United States
Johnny
The price is 3.558.329 ₫
4.144.980 ₫ total
includes taxes & fees
21 Jun - 22 Jun
Hilton St. Louis Frontenac

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.6 out of 10, Excellent, (1,001 reviews)
"Great stay and so much to do close by!"
United States
Rachel
The price is 3.733.613 ₫
4.440.348 ₫ total
includes taxes & fees
20 Jun - 21 Jun
St. Louis Union Station Hotel, Curio Collection by Hilton

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,003 reviews)
"Great stay!"
United States
Matiah
The price is 4.189.985 ₫
5.333.488 ₫ total
includes taxes & fees
1 Jul - 2 Jul
Ameristar Casino Resort and Spa

Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (721 reviews)
"Clean room & good included breakfast "
United Kingdom
Felix
The price is 4.675.570 ₫
5.504.923 ₫ total
includes taxes & fees
19 Jun - 20 Jun
Le Méridien St. Louis Clayton

DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End
8.2 out of 10, Very good, (1,001 reviews)
"Excellent location"
United States
Leticia
The price is 3.647.287 ₫
4.301.209 ₫ total
includes taxes & fees
21 Jun - 22 Jun
DoubleTree by Hilton St. Louis Forest Park

The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1,003 reviews)
"The staff was pleasant and the property was clean."
United States
Bayyan
The price is 3.914.162 ₫
4.576.789 ₫ total
includes taxes & fees
18 Jun - 19 Jun
The Westin St. Louis

Marriott St. Louis Grand

Marriott St. Louis Grand
4.0 star property
Downtown St. Louis
8.2 out of 10, Very good, (1,012 reviews)
"The room was nice and the staff was friendly. Perfect spot to stay if you’re going out on the town for the night."
United States
Jenna
The price is 4.711.101 ₫
5.602.866 ₫ total
includes taxes & fees
4 Jun - 5 Jun
Marriott St. Louis Grand

Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
Downtown St. Louis
7.6 out of 10, Good, (1,153 reviews)
"The breakfast was yummy"
United States
Annie
The price is 5.060.617 ₫
6.018.365 ₫ total
includes taxes & fees
12 Jun - 13 Jun
Hilton St. Louis at the Ballpark

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,331 reviews)
"Great staff,Good breakfast!"
United States
Virendra
The price is 3.755.195 ₫
4.466.015 ₫ total
includes taxes & fees
11 Jun - 12 Jun
Embassy Suites by Hilton St. Louis Downtown

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1,959 reviews)
"Amazing place to stay. We’ve been a half dozen times and are never disappointed."
United States
Brian
The price is 3.730.718 ₫
4.437.120 ₫ total
includes taxes & fees
21 Jun - 22 Jun
Moonrise Hotel

The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.8 out of 10, Excellent, (1,007 reviews)
"Good unique stay."
United States
Caleb
The price is 4.242.360 ₫
5.037.294 ₫ total
includes taxes & fees
21 Jun - 22 Jun
The Cheshire

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,069 reviews)
"Great location and staff."
United States
Colette
The price is 3.431.471 ₫
4.046.700 ₫ total
includes taxes & fees
14 Jun - 15 Jun
Hilton Pennywell St. Louis at the Arch

HoteLumiere at the Arch - A Caesars Rewards Destination

HoteLumiere at the Arch - A Caesars Rewards Destination
4.0 star property
Downtown St. Louis
6.8 out of 10, (1,005 reviews)
"Very nice rooms, private connected entrance to casino, helpful staff. Great place to stay that is worth the money."
United States
Michael
The price is 2.597.290 ₫
3.652.060 ₫ total
includes taxes & fees
1 Jul - 2 Jul
HoteLumiere at the Arch - A Caesars Rewards Destination
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in St. Charles.
Still don't see what you're looking for?
See all properties in St. Charles.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about St. Charles

Stroll down Historic Main Street, where 1812-era charm meets modern boutiques and eateries. Bike the scenic Katy Trail or try your luck at Ameristar Casino before exploring the Lewis & Clark Boathouse.

Dramatic sunrise panoramic view of the Veterans Memorial Bridge over the Missouri River at St. Charles, MO

Top St. Charles Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in St. Charles?
Look forward to 4-star hotel comfort at Ameristar Casino Resort and Spa. Rated highly by many of our guests, it features spa facilities and a spa tub. Also check out DoubleTree by Hilton St. Louis - Westport. Concierge services and a pillowtop mattress make this retreat another in-demand pick in St. Charles.
How much does it cost to stay in a 4-star hotel in St. Charles?
To find a 4-star hotel in St. Charles that fits your budget, use Expedia's sort and search filters. Check out the availability during your holiday dates and use our pricing filter to set your maximum rate. You can also list your results by the most wallet-friendly option first.

  • Search for the lowest price from 10.925.017 ₫

What's the difference between 5-star and 4-star hotels in St. Charles?
Treat yourself to luxury during your St. Charles getaway by choosing a 4-star hotel. As well as featuring upmarket surroundings, these properties are typically filled with amenities like large beds, complimentary bathrobes and more. A 5-star hotel will go above and beyond to make your stay an even more indulgent and special one. Round-the-clock concierge assistance, elegant furnishings and gourmet dining are just the start of the first-rate services and conveniences you'll likely have access to.