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Our top choices for Mesonisia 5-star hotels

Nautilux Rethymno by Mage Hotels

Nautilux Rethymno by Mage Hotels
5.0 star property
Perivolia
9.8 out of 10, Exceptional, (351 reviews)
"Great ammenities, comfortable rooms, good food and attentive staff. Excellent stay!"
Australia
Mark
The price is 3.888.129 ₫
4.883.354 ₫ total
includes taxes & fees
9 Apr - 10 Apr
Nautilux Rethymno by Mage Hotels

The Royal Senses Resort & Spa Crete, Curio Collection Hilton

The Royal Senses Resort & Spa Crete, Curio Collection Hilton
5.0 star property
Mylopotamos
9.2 out of 10, Wonderful, (117 reviews)
"Amazing service and staff"
Canada
Bianca
The price is 5.947.087 ₫
7.352.041 ₫ total
includes taxes & fees
23 Apr - 24 Apr
The Royal Senses Resort & Spa Crete, Curio Collection Hilton

Atlantis Beach Hotel

Atlantis Beach Hotel
5.0 star property
Rethymno
9.2 out of 10, Wonderful, (94 reviews)
"Wonderful hotel in good location. Just a short walk to the old town for shopping, dinning, etc."
United States
David
The price is 2.999.751 ₫
3.874.164 ₫ total
includes taxes & fees
9 Apr - 10 Apr
Atlantis Beach Hotel

Aquila Porto Rethymno

Aquila Porto Rethymno
5.0 star property
Rethymno
9.0 out of 10, Wonderful, (126 reviews)
"Breakfast was great, beach access excellent"
United States
roman
The price is 3.144.900 ₫
4.039.414 ₫ total
includes taxes & fees
6 Apr - 7 Apr
Aquila Porto Rethymno

Grecotel Creta Palace

Grecotel Creta Palace
5.0 star property
Rethymno
8.8 out of 10, Excellent, (122 reviews)
"Table and chairs on our own patio surrounded by beautifully tended gardens - perfect for the beginning and end of each day - staff were excellent "
United Kingdom
Valerie Sarah
Grecotel Creta Palace

Iberostar Selection Creta Marine

Iberostar Selection Creta Marine
5.0 star property
Mylopotamos
8.4 out of 10, Very good, (88 reviews)
"Lovely 7 night stay. "
United Kingdom
Helen
The price is 3.943.632 ₫
4.948.895 ₫ total
includes taxes & fees
10 Apr - 11 Apr
Iberostar Selection Creta Marine

Grecotel LUXME White

Grecotel LUXME White
5.0 star property
Rethymno
9.0 out of 10, Wonderful, (172 reviews)
"Amazing hotel, family friendly with exceptional food. "
United Kingdom
Zawen
The price is 9.292.836 ₫
11.036.651 ₫ total
includes taxes & fees
26 Apr - 27 Apr
Grecotel LUXME White

The Royal Blue

The Royal Blue
5.0 star property
Mylopotamos
9.2 out of 10, Wonderful, (172 reviews)
"Simply a perfect property to enjoy wonderful days on Crete. Nice and comfortable rooms, great food, very nice staff."
Germany
Christopher
The price is 4.226.518 ₫
5.268.600 ₫ total
includes taxes & fees
20 Apr - 21 Apr
The Royal Blue

Aquila Rithymna Beach

Aquila Rithymna Beach
5.0 star property
Rethymno
8.4 out of 10, Very good, (63 reviews)
"Fantastic place for kids and families "
United Kingdom
Viviana
Aquila Rithymna Beach

Rethymno Palace

Rethymno Palace
5.0 star property
Rethymno
8.4 out of 10, Very good, (71 reviews)
"Great place and value for money."
Denmark
Maria
Rethymno Palace

Kyma Suites Beach Hotel

Kyma Suites Beach Hotel
5.0 star property
Rethymno
8.8 out of 10, Excellent, (58 reviews)
"Friendly staff, comfortable room, BEST location in all of Rethymnon between the beach and old town."
Canada
Christina
The price is 2.601.983 ₫
3.084.110 ₫ total
includes taxes & fees
27 Mar - 28 Mar
Kyma Suites Beach Hotel

Nalu Resort & Spa

Nalu Resort & Spa
5.0 star property
Rethymno
9.4 out of 10, Exceptional, (25 reviews)
"Fantastic hotel, great rooms with amazing pillows ! Staff very polite and friendly."
United Kingdom
Natalie
The price is 2.612.583 ₫
3.096.767 ₫ total
includes taxes & fees
31 Mar - 1 Apr
Nalu Resort & Spa

AMIRA LUXURY RESORT & SPA

AMIRA LUXURY RESORT & SPA
5.0 star property
Rethymno
9.8 out of 10, Exceptional, (44 reviews)
"Great location with excellent food "
United Kingdom
Paul
AMIRA LUXURY RESORT & SPA

Caramel, A Grecotel Resort to Live

Caramel, A Grecotel Resort to Live
5.0 star property
Rethymno
9.6 out of 10, Exceptional, (79 reviews)
"Quite and relaxing."
United States
Brian
The price is 7.433.589 ₫
8.919.770 ₫ total
includes taxes & fees
26 Apr - 27 Apr
Caramel, A Grecotel Resort to Live

Uzenie All Suites Boutique Resort

Uzenie All Suites Boutique Resort
5.0 star property
Rethymno
10.0 out of 10, Exceptional, (6 reviews)
"Wir als Paar waren von der Anlage sehr begeistert. Das Personal ist hervorragend da die Unterkunft seit Juni 2025 erst geöffnet hat ist alles neu und auch super gereinigt. Man kann in der Anlage richtig schön entspannen und seine Auszeit genießen. Absolute Empfehlung und auch gerne mal wieder. Was uns nicht gefallen hat, war der Transfer mit Danaos Travel vom Flughafen Heraklion aus. Hier die Empfehlung mit eigenem Leihwagen oder den privaten Transfer anzureisen. Kommen jederzeit sehr sehr...
Germany
Benjamin
The price is 7.426.709 ₫
8.914.254 ₫ total
includes taxes & fees
25 Apr - 26 Apr
Uzenie All Suites Boutique Resort

Minos Ambassador - Adults only

Minos Ambassador - Adults only
5.0 star property
Rethymno
8.4 out of 10, Very good, (9 reviews)
"Great location near Rethymno. Nice hotel with lovely staff and rooms."
United Kingdom
Tshepo
The price is 3.180.042 ₫
4.076.922 ₫ total
includes taxes & fees
21 Apr - 22 Apr
Minos Ambassador - Adults only

La Mer Resort & Spa Crete

La Mer Resort & Spa Crete
5.0 star property
Apokoronas
8.8 out of 10, Excellent, (150 reviews)
"Beautiful location, comfortable rooms and amazing service. "
United States
Sarah
The price is 2.902.985 ₫
3.764.000 ₫ total
includes taxes & fees
2 Apr - 3 Apr
La Mer Resort & Spa Crete

Aegean Pearl

Aegean Pearl
5.0 star property
Perivolia
8.6 out of 10, Excellent, (70 reviews)
"Fantastic room, courteous staff and gorgeous pool/ breakfast area."
United States
Georgios
Aegean Pearl

Oros Luxury Beach Resort

Oros Luxury Beach Resort
5.0 star property
Rethymno
8.6 out of 10, Excellent, (10 reviews)
"Great place, fantastic service, great rooms, a MUST"
United States
Tal
Oros Luxury Beach Resort

Atermono Boutique Resort & Spa

Atermono Boutique Resort & Spa
5.0 star property
Rethymno
9.0 out of 10, Wonderful, (59 reviews)
"Amazing experience, great location, great service"
Sweden
Gustav
Atermono Boutique Resort & Spa
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Frequently asked questions

How much does it cost to stay in a 5-star hotel in Mesonisia?
You can find a range of pricing options for a 5-star hotel in Mesonisia on Expedia. The amount you pay will depend on when you want to travel, length of stay and other factors. Compare all of the available properties for your chosen dates and make use of our pricing and other filters to find the perfect high-end stay.

  • Search for the lowest price per night from 2.450.578 ₫

What makes a hotel 5 stars in Mesonisia?
From high-end dining venues and 24-hour fitness centres to pools and premium bedding, the 5-star experience in Mesonisia is all about indulgence and comfort. But it calls for more than just upscale conveniences to earn a 5-star rating. Stays must also deliver outstanding guest-focused services like massage treatments, on-site dry cleaning and laundry and 24-hour room service.
Are there any 5-star all-inclusive resorts in Mesonisia?
Use our convenient filters to find an upscale retreat in Mesonisia where everything you need is included. From there, narrow your results for resorts that have a rating of 5 stars and are categorised as "All inclusive." The first thing on the itinerary at these stays? Pure enjoyment and indulgence.