A large eye sculpture in a park surrounded by trees.

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Check availability on Northeast Missouri 5 Star Hotels

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

Our top choices for Northeast Missouri 5-star hotels

An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.

1. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (586 reviews)
"Incredible stay! Loved the room, the staff were great, and the amenities were amazing! Definitely recommend staying here!"
United States
Kennedy
The price is 14.699.546 ₫
17.160.235 ₫ total
includes taxes & fees
27 Nov - 28 Nov
The Ritz-Carlton, St. Louis
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Northeast Missouri.
21C Museum Hotel St Louis

21C Museum Hotel St Louis

1528 Locust street St. Louis MO
The price is 3.711.054 ₫ per night from 22 Nov to 23 Nov
3.711.054 ₫
4.468.468 ₫ total
22 Nov - 23 Nov
includes taxes & fees
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Northeast Missouri

Great live music, sports teams and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theatres.

See all hotels in Northeast Missouri
A large eye sculpture in a park surrounded by trees.
Photo by Andrew Hershfeld
Open Photo by Andrew Hershfeld

Top Northeast Missouri Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Northeast Missouri?
The amount you pay for a 5-star hotel in Northeast Missouri can vary depending on the time of year you travel and how long you plan to stay, among a range of factors. Use our price per night filter and other search tools to find the best rate on a high-end stay.

  • Search for the lowest price per night from 3.360.762 ₫

What makes a hotel 5 stars in Northeast Missouri?
In Northeast Missouri, a hotel must offer a certain level of top-notch amenities to be designated 5 stars. These can include saunas and spas, on-site gyms, gourmet restaurants, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their guest-focused service. You can expect things like concierge services, nightly turn-down services and in-room massage. Some may even offer thoughtful touches such as a welcome gift.
Are there any 5-star all-inclusive resorts in Northeast Missouri?
Our convenient filters are the quickest way to narrow down what you're looking for. Select "All inclusive" and "5-star" to show the most luxurious properties in Northeast Missouri where your meals, room, entertainment and activities are included in the upfront price. At these retreats, your trip is absolute indulgence from the moment you put down your suitcase.