Our top choices for Northeast Missouri hotels

Room, 2 Queen Beds, Non Smoking | In-room safe, desk, blackout curtains, iron/ironing board

Super 8 by Wyndham Washington

Washington

Brenda

2.528.947 ₫ total

includes taxes & fees

24 Jan - 25 Jan

Depot Inn and Suites

La Plata

Maggie

2.365.927 ₫ total

includes taxes & fees

25 Jan - 26 Jan

Club Suite, 1 King Bed, Hot Tub | Private spa tub

Pinemark Inn & Suites

St. Clair

Toni

3.673.370 ₫ total

includes taxes & fees

19 Jan - 20 Jan

Sleep Inn & Suites Hannibal West

Hannibal

Vic

2.819.906 ₫ total

includes taxes & fees

8 Feb - 9 Feb

Holiday Inn Express & Suites Wentzville St Louis West by IHG

Wentzville

Erika

4.226.049 ₫ total

includes taxes & fees

23 Jan - 24 Jan

Motel 6 Hazelwood, MO

Hazelwood

Zaylee

1.921.724 ₫ total

includes taxes & fees

1 Feb - 2 Feb

Quality Inn & Suites Hannibal West

Hannibal

Steve

2.225.794 ₫ total

includes taxes & fees

25 Jan - 26 Jan

Baymont by Wyndham Warrenton

Warrenton

Columbus

2.218.279 ₫ total

includes taxes & fees

20 Jan - 21 Jan

Inns at St. Albans

Saint Albans

Paul

5.577.282 ₫ total

includes taxes & fees

20 Jan - 21 Jan

Comfort Suites St Charles - St Louis

St. Charles

Jere

2.303.775 ₫ total

includes taxes & fees

25 Jan - 26 Jan

Super 8 by Wyndham Union

Union

CYNTHIA K

2.298.700 ₫ total

includes taxes & fees

17 Feb - 18 Feb

Heritage Hotel Quincy

Quincy

Katherine

1.769.157 ₫ total

includes taxes & fees

19 Jan - 20 Jan

Desk, iron/ironing board, WiFi, bed sheets

Best Western On The River

Hannibal

Jennifer

3.016.813 ₫ total

includes taxes & fees

25 Jan - 26 Jan

Drury Inn & Suites Southwest St. Louis

Valley Park

Maureen

3.534.109 ₫ total

includes taxes & fees

25 Jan - 26 Jan

Holiday Inn Express & Suites St Peters by IHG

St. Peters

Martha

3.208.060 ₫ total

includes taxes & fees

22 Jan - 23 Jan

Embassy Suites by Hilton St. Louis St. Charles

St. Charles

Scott

3.689.057 ₫ total

includes taxes & fees

25 Jan - 26 Jan

Quality Inn Foristell

Foristell

Karen

2.194.409 ₫ total

includes taxes & fees

20 Jan - 21 Jan

Best Western Plus The Charles Hotel

St. Charles

Becky

2.653.210 ₫ total

includes taxes & fees

21 Jan - 22 Jan

Drury Plaza Hotel St. Louis St. Charles

St. Charles

John Christopher

3.502.057 ₫ total

includes taxes & fees

25 Jan - 26 Jan

Country Inn & Suites by Radisson, St. Charles Historic District

St. Charles Historic District

Audrey

3.369.608 ₫ total

includes taxes & fees

25 Jan - 26 Jan

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Holiday Rentals in Northeast Missouri

Apartment

White House at Grand Central

Grand Center

"Very clean and very friendly people "

Apartment

Lakefront Studio Guest Home on Hermann Wine Trail!

New Haven

"Loved this property, very clean and well kept! Very pretty, lovely view. "

Apartment

Spacious 3-Bedroom with King Bed

Central West End

"Overall, we loved the apartment. It was cute, beds were very comfortable. "

Apartment

Lovely Couples Escape on Mississippi River!

St. Charles

"Amazing place to stay, quiet and relaxing would definitely stay there again"

Cottage

Peaceful Guest Home w/ Patio on 152-acre Farm

Berger

"Very clean,family friendly, even though it was 7 miles out of town they were very Accommodating,they came to puck us up at the train station and there's a van that will take you into town and you can take the trolley to all the wineries,shopping, we all loved our stay,i would definitely recommend to anyone who enjoys the fram life, they have lots of history, and animals, thank you Susan and Mike for all that you did to make our stay memorable, we would definitely come back. "

Cottage

Hillside Cabin on 43 Acres w/ Private Lake & View!

Defiance

"We had a wonderful stay. The property is beautiful and well maintained, and the cabin is cute, comfortable, and well equipped. Nick is a very courteous host. We couldn’t have hoped for a better Thanksgiving getaway!"

Cottage

Home w/ Trail Access on 19 Acres in Wright City!

Wright City

"Great house in a beautiful setting. We enjoyed the quiet solitude and woodsy area. Very clean accommodations with every amenity available. "

Apartment

Walk to Mississippi River: Grafton Townhome!

Grafton

"The property exceeded our expectations and was perfect for our stay!"

Holiday Home

Forest Park Oasis | JZ Vacation Rentals

Kings Oak

"Great property with plenty of space. Nice sized dining room table for dinner. Beautiful family room and fire place. Nicely decorated. "

Apartment

New Melle Apartment Near Missouri Wine Country

Wentzville

"Apartment was wonderful! Very spacious and lots of furniture. Had a flat screen in the living room and bedroom that included Netflix and Prime. Air conditioner worked very well. Was very quiet and in a good location. Property manager was very friendly. There was even a very nice tea selection included with our stay. All amenities including, fridge, sinks, countertop burner, shower, washer, dryer, and toilet worked with no issues. All the dishes and mugs were clean. Plenty of towels to use during...

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Stay near popular Central United States attractions

Busch Stadium

4.6/5 (2,624 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

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Caption---- Penguins at The St. Louis, MO Zoo

St. Louis Zoo

4.6/5 (2,379 reviews)

Why not visit the animals who live at St. Louis Zoo during your holiday in St. Louis? Amble around the area's lush forest or attend a sporting event.

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Learn more about Northeast Missouri

Great live music, sports teams and popular sights from St. Louis Union Station to Busch Stadium—explore Northeast Missouri, a family-friendly destination also known for its theatres.

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Grant\'s Farm which includes heritage architecture

Top Northeast Missouri Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent

"Staff was amazing! Room was nothing fancy at all, it looked like they had tacked up part of the wall paper? Anyhow, it was a good location and it was a super short 6 hours we needed the room so worked!"