Compare and book 5 Star hotels in Port Isabel, Texas

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Port Isabel 5 Star Hotels

Tonight
23 Aug - 24 Aug
Tomorrow
24 Aug - 25 Aug
Next weekend
29 Aug - 31 Aug
In two weeks
5 Sep - 7 Sep

Top Port Isabel 5 Star Hotels

Our top choices for Port Isabel 5-star hotels

Spacious Bay
Outdoor pool

Spacious Bay

5.0 star property
Spacious Bay
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Port Isabel.
Margaritaville Beach Resort South Padre Island

Margaritaville Beach Resort South Padre Island

310 Padre Blvd, South Padre Island, TX
The price is 3.060.164 ₫ per night from 10 Sept to 11 Sept
3.060.164 ₫
4.045.875 ₫ total
10 Sept - 11 Sept
includes taxes & fees
8.6/10 Excellent! (1,565 reviews)
Still don't see what you're looking for?
See all properties in Port Isabel.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Port Isabel

Climb the historic lighthouse for sweeping views of South Padre Island and spot dolphins playing in the turquoise waters. Explore the treasures at Pirates Landing pier, where fishing adventures and fresh seafood restaurants create the perfect coastal getaway.

See all hotels in Port Isabel

Top Port Isabel Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Port Isabel?
You'll find many different pricing options for a 5-star hotel in Port Isabel on Expedia. How much you'll pay will depend on your travel dates, trip length and other factors. Compare all of the available properties for your desired dates and make use of our pricing and other filters to discover the perfect luxury stay.

  • Search for the lowest price per night from 3.060.164 ₫

What makes a hotel 5 stars in Port Isabel?
From fine dining venues and 24/7 fitness centres to swimming pools and luxury bedding, the 5-star experience in Port Isabel is all about relaxation and luxury. But it takes more than just upscale amenities to earn a 5-star rating. Hotels must also deliver superior guest-focused services like in-room massage treatments, on-site dry cleaning and laundry and 24-hour room service.
Are there any 5-star all-inclusive resorts in Port Isabel?
Our filters are the quickest way to search for exactly what you want. Check the "All inclusive" and "5-star" boxes to see the most luxurious properties in Port Isabel where your accommodation, meals, entertainment and activities are included in the price. At these retreats, your trip is pure relaxation and indulgence from the moment you enter the lobby.