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Recommended hotels in Cape Girardeau

Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1001)
"Great place and staff, very accommodating!"
United States
Megan
The price is 2.369.527 ₫
2.672.860 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1004)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
The price is 2.185.210 ₫
2.310.282 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Drury Inn & Suites Jackson MO
Exterior
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
8.8 out of 10, Excellent, (669)
"Great place "
United States
GUY
The price is 2.215.754 ₫
2.397.999 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Front of property
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1002)
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is 1.842.907 ₫
2.079.096 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Pear Tree Inn Cape Girardeau Near the Medical Center
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
United States
Brian
The price is 2.501.445 ₫
2.821.979 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lobby
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (468)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
The price is 3.054.396 ₫
3.461.058 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Courtyard by Marriott Cape Girardeau Downtown
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (139)
"Nice hotel, clean and comfortable "
United States
Laura
The price is 2.317.128 ₫
2.614.045 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Fairfield Inn & Suites by Marriott Cape Girardeau
Lobby sitting area
The Riverview

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (474)
"The room was clean and the mattress was extremely comfortable "
United States
Stacy
The price is 3.009.633 ₫
3.395.287 ₫ total
includes taxes & fees
21 Dec - 22 Dec
The Riverview
Lobby
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (784)
"Excellent stay"
United States
Christina
The price is 2.677.336 ₫
3.020.409 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn Cape Girardeau I 55 East
Free daily buffet breakfast
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1003)
"Very friendly staff and great breakfast"
United States
Ray
The price is 2.369.527 ₫
2.672.860 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Drury Inn & Suites Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau Hotel Reviews

Frequently asked questions

What can I expect on my historical trip to Cape Girardeau?
Sights with historical relevance in Cape Girardeau are probably a big part of your travel plans. While you're here, you can visit the shops and riverfront. And also relish a stop at the top-notch restaurants in this family-friendly area.
How many historical hotels are there in Cape Girardeau?
In Cape Girardeau, you'll find 57 hotels and other lodging options bookable on Expedia though not many historic hotels to choose from.
What are the top historical places and other sights to visit in Cape Girardeau?
Cape Girardeau is notable for landmarks like Fort D Historic Site. Families come for attractions such as Cape Splash Family Aquatic Center, Cape Girardeau Conservation Nature Center and Lazy L Safari Park. A couple of additional sights to add to your itinerary are Isle Casino Cape Girardeau and Show Me Center.
What is a historic hotel like in Cape Girardeau?
Historic hotels give guests an opportunity to stay in a building that has been recognised with an official historic designation. Historic hotels throughout the world come in all forms like palaces, castles, stately homes or even lodges, pubs or skyscrapers — as long as it's of special interest. These types of hotels in Cape Girardeau often preserve original elements like traditional architecture and period features within the guestrooms or public spaces.
What is the difference between a historic hotel and a heritage hotel?
You'll often hear the term "heritage hotel" in Asia and Europe, wheareas the term "historic hotel" is more commonly used in the U.S. though overall the terms are quite similar. The building and architecture of historic hotels are generally what's most significant. For heritage hotels, mainly, it's cultural value as well as how it influenced the community.
Do historic hotels in Cape Girardeau have modern facilities?
Hotels have the safety features and modern conveniences you've come to expect, while every effort is made to preserve the historic aspects and traditions. Smart TVs, WiFi, updated bathroom facilities and the normal amenities found in any hotel will also be available in a historic hotel. Rest assured that when you select a historic hotel in Cape Girardeau, you won't find a place that is rundown or uncomfortable.