Search Luxury Hotels in Cape Girardeau

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Check availability on Cape Girardeau Luxury Hotels

Tonight
29 Sep - 30 Sep
Tomorrow
30 Sep - 1 Oct
This weekend
3 Oct - 5 Oct
Next weekend
10 Oct - 12 Oct

Top Cape Girardeau Luxury Hotels

Pear Tree Inn Cape Girardeau Near the Medical Center
Lobby

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1010)
"Staff was friendly, room was clean, good location, good rate."
The price is 1.847.946 ₫
2.084.781 ₫ total
includes taxes & fees
5 Oct - 6 Oct
Pear Tree Inn Cape Girardeau Near the Medical Center
Quality Inn
Lobby

Quality Inn

2.5 star property
7.2 out of 10, Good, (644)
"nice stay"
The price is 1.600.550 ₫
1.805.645 ₫ total
includes taxes & fees
16 Oct - 17 Oct
Quality Inn
Drury Inn & Suites Cape Girardeau
Business centre

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (1006)
"Excellent place. Really friendly staff"
The price is 2.376.006 ₫
2.680.169 ₫ total
includes taxes & fees
5 Oct - 6 Oct
Drury Inn & Suites Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau Hotel Reviews

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Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Cape Girardeau?
Use Expedia to arrange your flight to Cape Girardeau, MO (CGI-Cape Girardeau Municipal) airport or Cairo, IL (CIR-Cairo Regional) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a holiday, so we make it easy to get what you want to make your stay relaxing and comfortable. If you want an upscale hotel that has fine dining, a spa or several swimming pools, Expedia can help you find the best luxury hotel experience that Cape Girardeau has to offer. During your visit, you might want to enjoy the university which Cape Girardeau is known for.
When can I expect good weather in Cape Girardeau?
Planning for the weather is an important factor for making your trip to Cape Girardeau a success, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Cape Girardeau is 1495 mm.
What's there to see and do in Cape Girardeau?
Enjoy all that Cape Girardeau has to offer and visit Isle Casino Cape Girardeau, Show Me Center and Hunter Valley Winery. If you have a bit of extra time while you're in the area, you might want to check out Trail of Tears State Park and Shawnee National Forest.