Photo by Alice Burghart

Search Luxury Hotels in Cape Girardeau

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Cape Girardeau Luxury Hotels

Tonight
20 Dec - 21 Dec
Tomorrow
21 Dec - 22 Dec
Next weekend
26 Dec - 28 Dec
In two weeks
2 Jan - 4 Jan

Our top choices for Cape Girardeau luxury hotels

Lobby sitting area
The Riverview

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (474)
"The room was clean and the mattress was extremely comfortable "
United States
Stacy
The price is 2.534.134 ₫
2.858.859 ₫ total
includes taxes & fees
22 Dec - 23 Dec
The Riverview
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Cape Girardeau Hotel Reviews

Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Cape Girardeau?
Use Expedia to arrange your flight to Cape Girardeau, MO (CGI-Cape Girardeau Municipal) airport or Cairo, IL (CIR-Cairo Regional) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a holiday, so we make it easy to get what you want to make your stay relaxing and comfortable. If you want an upscale hotel that has fine dining, a spa or several swimming pools, Expedia can help you find the best luxury hotel experience that Cape Girardeau has to offer. During your visit, you might want to enjoy the university which Cape Girardeau is known for.
When can I expect good weather in Cape Girardeau?
Planning for the weather is an important factor for making your trip to Cape Girardeau a success, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Cape Girardeau is 1495 mm.
What's there to see and do in Cape Girardeau?
Enjoy all that Cape Girardeau has to offer and visit Isle Casino Cape Girardeau, Show Me Center and Hunter Valley Winery. If you have a bit of extra time while you're in the area, you might want to check out Trail of Tears State Park and Shawnee National Forest.