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Search Hotels in Central San Mateo, San Francisco

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Our top choices for Central San Mateo hotels

Exterior
Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG

Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG

Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG
3.0 star property
Central San Mateo
7.8 out of 10, Good, (1000)
"Close to good restaurants!"
United States
Paula Marie
The price is 2.579.752 ₫
2.984.615 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG
House | 3 bedrooms
Sanmateo Cozy Central 3b1b Home Garage Parking AC

Sanmateo Cozy Central 3b1b Home Garage Parking AC

Sanmateo Cozy Central 3b1b Home Garage Parking AC
2.0 star property
Central San Mateo
The price is 7.190.868 ₫
13.406.007 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Sanmateo Cozy Central 3b1b Home Garage Parking AC
Exterior
The Westin San Francisco Airport

The Westin San Francisco Airport

The Westin San Francisco Airport
4.0 star property
6.4 km from Central San Mateo
8.8 out of 10, Excellent, (2035)
"Comfortable room, welcome glass of wine, easy shuttle to and from airport, friendly staff."
United States
Carole
The price is 2.709.266 ₫
3.884.719 ₫ total
includes taxes & fees
21 Dec - 22 Dec
The Westin San Francisco Airport
Lobby sitting area
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
28.2 km from Central San Mateo
9.0 out of 10, Wonderful, (7186)
"Good location and great hotel to stay, the bed was very comfortable and the breakfast was good with lots of options! "
Canada
Veronica
The price is 2.829.089 ₫
4.414.246 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Riu Plaza Fisherman's Wharf
Breakfast, lunch, dinner served; local cuisine
DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport
4.0 star property
3.8 km from Central San Mateo
8.6 out of 10, Excellent, (1364)
"Nice hotel and area "
Canada
Robert
The price is 2.784.553 ₫
3.165.898 ₫ total
includes taxes & fees
24 Dec - 25 Dec
DoubleTree by Hilton San Francisco Airport
Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds
Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf
4.0 star property
28.3 km from Central San Mateo
9.0 out of 10, Wonderful, (3840)
"Excellent stay and great location! "
United States
CHRISTINE
The price is 3.198.366 ₫
4.972.589 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Caza Fisherman's Wharf
Front of property – evening/night
Hilton San Francisco Financial District

Hilton San Francisco Financial District

Hilton San Francisco Financial District
4.0 star property
26.7 km from Central San Mateo
8.8 out of 10, Excellent, (2140)
"Great hotel "
United States
Tanya
The price is 2.760.861 ₫
3.249.396 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hilton San Francisco Financial District
Terrace/patio
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco
4.0 star property
26.6 km from Central San Mateo
8.8 out of 10, Excellent, (2810)
"Clean and comfortable room, good staff, great location. "
United Kingdom
David
The price is 2.639.771 ₫
3.107.022 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Club Quarters Hotel in San Francisco
Exterior
Hotel Aluxor SFO

Hotel Aluxor SFO

Hotel Aluxor SFO
2.5 star property
10.1 km from Central San Mateo
8.6 out of 10, Excellent, (2574)
"Great room loved the type of hotel."
United States
Eugenia
Hotel Aluxor SFO
American cuisine
Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront
4.0 star property
3.4 km from Central San Mateo
8.6 out of 10, Excellent, (2735)
"Nice airport hotel…staff was great, breakfast was amazing "
United States
Lynne
The price is 2.461.422 ₫
2.798.514 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Hilton San Francisco Airport Bayfront
Premium bedding, pillow-top beds, in-room safe, desk
Hotel 1550

Hotel 1550

Hotel 1550
3.5 star property
8.7 km from Central San Mateo
9.0 out of 10, Wonderful, (1045)
"Great front desk experience, nice room and very convenient to the airport. "
United States
Elmaz
The price is 2.668.493 ₫
3.158.074 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Hotel 1550
Cocktail bar, pool views, open daily
Shashi Hotel Mountain View Palo Alto

Shashi Hotel Mountain View Palo Alto

Shashi Hotel Mountain View Palo Alto
5.0 star property
27.3 km from Central San Mateo
9.4 out of 10, Exceptional, (1193)
"Perfect place to stay and enjoy "
United States
Ali
The price is 3.624.815 ₫
3.994.365 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Shashi Hotel Mountain View Palo Alto
Lobby sitting area
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square
3.5 star property
26.1 km from Central San Mateo
9.4 out of 10, Exceptional, (3063)
"Best location, friendly staff, had a wonderful time stayed! "
United States
Kalinda
The price is 1.994.309 ₫
2.356.478 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Chancellor Hotel on Union Square
Exterior
King George Hotel

King George Hotel

King George Hotel
3.0 star property
25.9 km from Central San Mateo
8.6 out of 10, Excellent, (2102)
"Great place!"
United States
Troy
The price is 2.227.603 ₫
3.016.480 ₫ total
includes taxes & fees
21 Dec - 22 Dec
King George Hotel
Free daily buffet breakfast
Holiday Inn Express and Suites Fisherman's Wharf by IHG

Holiday Inn Express and Suites Fisherman's Wharf by IHG

Holiday Inn Express and Suites Fisherman's Wharf by IHG
3.0 star property
28.2 km from Central San Mateo
9.0 out of 10, Wonderful, (2226)
"The room was nice and clean. The staff were very friendly! We enjoyed our stay!"
United States
Theresa
The price is 2.764.755 ₫
4.043.909 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Holiday Inn Express and Suites Fisherman's Wharf by IHG
Exterior
Handlery Union Square Hotel

Handlery Union Square Hotel

Handlery Union Square Hotel
3.5 star property
26 km from Central San Mateo
8.8 out of 10, Excellent, (2807)
"Clean hotel, great location, kind staff! "
United States
Felix
The price is 27.620.457 ₫
32.507.896 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Handlery Union Square Hotel
Games room
Hotel Zephyr San Francisco

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco
4.0 star property
28.3 km from Central San Mateo
8.6 out of 10, Excellent, (2338)
"Great decor and really great location"
United States
Jose
The price is 3.515.833 ₫
5.067.459 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Hotel Zephyr San Francisco
Snack bar
Hampton Inn & Suites Mountain View

Hampton Inn & Suites Mountain View

Hampton Inn & Suites Mountain View
2.5 star property
28.6 km from Central San Mateo
9.0 out of 10, Wonderful, (958)
"Nice place to stay"
United States
Douglas R.
The price is 2.568.696 ₫
2.830.575 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn & Suites Mountain View
Exterior
Half Moon Bay Lodge

Half Moon Bay Lodge

Half Moon Bay Lodge
3.0 star property
17 km from Central San Mateo
9.0 out of 10, Wonderful, (1080)
"Always great staff here, nice rooms, nice jacuzzi "
United States
Pamela
The price is 3.091.754 ₫
3.637.382 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Half Moon Bay Lodge
Property entrance
Good Nite Inn - Redwood City

Good Nite Inn - Redwood City

Good Nite Inn - Redwood City
2.5 star property
10.9 km from Central San Mateo
8.6 out of 10, Excellent, (1520)
"Just a nice stay"
United States
Francisco
The price is 2.105.920 ₫
2.378.637 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Good Nite Inn - Redwood City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Central San Mateo

Find the best Central San Mateo areas for the activities you enjoy most.
Union Square featuring a skyscraper and a city

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

Fisherman\'s Wharf featuring a bay or harbour

Fisherman's Wharf

Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and San Francisco Bay.

South of Market which includes skyline, a park and cbd

South of Market

Gourmet restaurants great entertainment and top sights from Oracle Park to San Francisco Bay – discover South of Market, a destination also famous for its shopping.

Nob Hill showing street scenes and a city

Nob Hill

Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.

Top Central San Mateo Hotel Reviews

Mayflower Hotel

Mayflower Hotel

10/10 Excellent
"Good location, blocks from Chinatown. Room was clean. Staff was friendly and very helpful. Breakfast was good. Elevator is vintage. Lobby is beautiful. All in all, very enjoyable. Would definitely recommend and stay again. "
Bell 5-night trip
Posted 3 days ago
Mayflower Hotel

Frequently asked questions

What is Central San Mateo like?
You'll be sure to have fun exploring San Mateo's Central San Mateo neighbourhood. Are you looking for Central San Mateo travel tips? Make sure that you visit The San Mateo Japanese Garden and Cinemark Century San Mateo 12 while you're in the neighbourhood.
How many hotels will I find in the Central San Mateo area?
Expedia has 45 hotels and other accommodation options in Central San Mateo to choose from, making this an ideal home base for exploring the greater San Mateo area.
If I need to cancel my hotel reservation in Central San Mateo, will I receive a refund?
Yes! The majority of room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within 24 hours of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to get the best deals in Central San Mateo.
What is there to do in this San Mateo neighbourhood?
A few attractions you might want to check out while you're in Central San Mateo are The San Mateo Japanese Garden and Cinemark Century San Mateo 12. While you're out sightseeing, Burlingame Museum of PEZ Memorabilia and Poplar Creek Golf Course are a couple of additional sights to visit in San Mateo.
How can I get around Central San Mateo and the greater San Mateo area?
If you want to venture out of town, San Mateo Station is the closest train station. You can also catch a ride at Hayward Park Station.