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Our top choices for Central San Mateo hotels

Exterior
Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG

Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG

Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG
3.0 star property
Central San Mateo
7.8 out of 10, Good, (1007)
"amazing soaps"
United States
Nickesh
The price is 2.472.858 ₫
2.860.886 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG
House | 3 bedrooms
Sanmateo Cozy Central 3b1b Home Garage Parking AC

Sanmateo Cozy Central 3b1b Home Garage Parking AC

Sanmateo Cozy Central 3b1b Home Garage Parking AC
2.0 star property
Central San Mateo
The price is 7.186.224 ₫
13.397.351 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Sanmateo Cozy Central 3b1b Home Garage Parking AC
Property grounds
Creekside Inn

Creekside Inn

Creekside Inn
3.5 star property
23.2 km from Central San Mateo
9.0 out of 10, Wonderful, (1637)
"Excellent beautiful and clean and safe wonderful location. "
United States
Debra
The price is 2.236.095 ₫
3.043.063 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Creekside Inn
Restaurant
Hampton Inn & Suites Mountain View

Hampton Inn & Suites Mountain View

Hampton Inn & Suites Mountain View
2.5 star property
28.6 km from Central San Mateo
9.0 out of 10, Wonderful, (955)
"Excellent location, service, price, and breakfast"
United States
Jennifer
The price is 2.504.426 ₫
2.759.752 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn & Suites Mountain View
Free daily buffet breakfast
Hampton Inn & Suites San Mateo-San Francisco Airport

Hampton Inn & Suites San Mateo-San Francisco Airport

Hampton Inn & Suites San Mateo-San Francisco Airport
3.0 star property
East San Mateo, 4.1 km from Central San Mateo
9.4 out of 10, Exceptional, (825)
"The room and hotel is beautiful, clean and comfortable. The staff are so wonderful and kind!"
United States
Julie
The price is 2.714.882 ₫
3.120.621 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn & Suites San Mateo-San Francisco Airport
Exterior
The Zen Hotel Palo Alto

The Zen Hotel Palo Alto

The Zen Hotel Palo Alto
3.0 star property
24.4 km from Central San Mateo
9.2 out of 10, Wonderful, (1288)
"Room was great, plenty of room & the breakfast was very good & tasty"
United States
ALFRED
The price is 2.343.954 ₫
2.711.726 ₫ total
includes taxes & fees
19 Dec - 20 Dec
The Zen Hotel Palo Alto
Property entrance
Menlo Park Inn

Menlo Park Inn

Menlo Park Inn
3.0 star property
17.1 km from Central San Mateo
9.0 out of 10, Wonderful, (1005)
"We've stayed here a few times and have always been happy with our choice. Friendly owners, good breakfast"
United States
Evan
The price is 2.430.767 ₫
2.825.372 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Menlo Park Inn
Lobby
Best Western Inn & Suites San Mateo - San Francisco Airport

Best Western Inn & Suites San Mateo - San Francisco Airport

Best Western Inn & Suites San Mateo - San Francisco Airport
2.5 star property
Shoreview, 1.9 km from Central San Mateo
8.8 out of 10, Excellent, (1259)
"Staff was great and check in was perfect."
United States
FLORENCE CARMELA
The price is 2.485.748 ₫
2.857.242 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Best Western Inn & Suites San Mateo - San Francisco Airport
Exterior
Aloft San Francisco Airport

Aloft San Francisco Airport

Aloft San Francisco Airport
3.0 star property
6.4 km from Central San Mateo
9.0 out of 10, Wonderful, (2236)
"All good, friendly staff, spotless room. "
United States
Michael
The price is 2.870.883 ₫
3.299.937 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Aloft San Francisco Airport
Outdoor banquet area
The Palo Alto Inn

The Palo Alto Inn

The Palo Alto Inn
3.0 star property
25 km from Central San Mateo
8.8 out of 10, Excellent, (972)
"Great stay! Thanks!"
United States
Michael
The price is 1.757.966 ₫
2.030.450 ₫ total
includes taxes & fees
19 Dec - 20 Dec
The Palo Alto Inn
Exterior
The Westin San Francisco Airport

The Westin San Francisco Airport

The Westin San Francisco Airport
4.0 star property
6.4 km from Central San Mateo
8.8 out of 10, Excellent, (2034)
"Room great, location and shuttle were excellent Enjoyed 2 restaurants and Starbucks on site. "
United States
Robert
The price is 2.707.516 ₫
3.882.210 ₫ total
includes taxes & fees
22 Dec - 23 Dec
The Westin San Francisco Airport
Property amenity
SpringHill Suites by Marriott Belmont Redwood Shores

SpringHill Suites by Marriott Belmont Redwood Shores

SpringHill Suites by Marriott Belmont Redwood Shores
2.5 star property
7.3 km from Central San Mateo
8.8 out of 10, Excellent, (1002)
"Really nice spot - preferable to the other nearby properties and a great value. "
United States
Fred
The price is 2.437.344 ₫
2.819.886 ₫ total
includes taxes & fees
20 Dec - 21 Dec
SpringHill Suites by Marriott Belmont Redwood Shores
Front of property
The Ameswell Hotel

The Ameswell Hotel

The Ameswell Hotel
4.5 star property
28.6 km from Central San Mateo
9.6 out of 10, Exceptional, (1133)
"Love our stay!"
United States
Lisa
The price is 3.601.166 ₫
4.022.322 ₫ total
includes taxes & fees
29 Dec - 30 Dec
The Ameswell Hotel
Poolside bar
Shashi Hotel Mountain View Palo Alto

Shashi Hotel Mountain View Palo Alto

Shashi Hotel Mountain View Palo Alto
5.0 star property
27.3 km from Central San Mateo
9.4 out of 10, Exceptional, (1191)
"Perfect place to stay and enjoy "
United States
Ali
The price is 3.527.769 ₫
3.887.424 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Shashi Hotel Mountain View Palo Alto
Balcony
The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay
2.5 star property
19.2 km from Central San Mateo
8.6 out of 10, Excellent, (2293)
"Clean, cozy, great staff!"
United States
Stacie
The Marina Inn on San Francisco Bay
Exterior
SFO El Rancho Inn SureStay Collection by Best Western

SFO El Rancho Inn SureStay Collection by Best Western

SFO El Rancho Inn SureStay Collection by Best Western
3.0 star property
8 km from Central San Mateo
8.4 out of 10, Very good, (2958)
"Rooms were very clean and the check in and check out was very quick. "
United States
Jacobo
The price is 2.548.622 ₫
2.948.628 ₫ total
includes taxes & fees
20 Dec - 21 Dec
SFO El Rancho Inn SureStay Collection by Best Western
Front of property
Inn at Rockaway San Francisco Pacifica

Inn at Rockaway San Francisco Pacifica

Inn at Rockaway San Francisco Pacifica
2.5 star property
15.9 km from Central San Mateo
8.2 out of 10, Very good, (1007)
"The rooms were clean. Nice beach view. The receptionist was very helpful and friendly! Lots of covered secured parking."
United States
Marquel Nichole
Inn at Rockaway San Francisco Pacifica
Café
Stanyan Park Hotel

Stanyan Park Hotel

Stanyan Park Hotel
3.0 star property
25.4 km from Central San Mateo
9.2 out of 10, Wonderful, (1003)
"I would stay here again, charming and wonderfully located. "
United States
Aaron Michael
The price is 4.510.203 ₫
5.245.930 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Stanyan Park Hotel
Exterior
Half Moon Bay Lodge

Half Moon Bay Lodge

Half Moon Bay Lodge
3.0 star property
17 km from Central San Mateo
9.0 out of 10, Wonderful, (1079)
"Always great staff here, nice rooms, nice jacuzzi "
United States
Pamela
The price is 3.089.758 ₫
3.635.034 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Half Moon Bay Lodge
Lobby sitting area
The Dylan at SFO

The Dylan at SFO

The Dylan at SFO
3.0 star property
6.6 km from Central San Mateo
9.2 out of 10, Wonderful, (1837)
"Room was comfortable and staff very helpful. "
United States
John
The price is 2.895.295 ₫
3.447.309 ₫ total
includes taxes & fees
19 Dec - 20 Dec
The Dylan at SFO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Central San Mateo

Find the best Central San Mateo areas for the activities you enjoy most.
Union Square featuring a skyscraper and a city

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

Fisherman\'s Wharf featuring a bay or harbour

Fisherman's Wharf

Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and San Francisco Bay.

South of Market which includes skyline, a park and cbd

South of Market

Gourmet restaurants great entertainment and top sights from Oracle Park to San Francisco Bay – discover South of Market, a destination also famous for its shopping.

Nob Hill showing street scenes and a city

Nob Hill

Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.

Top Central San Mateo Hotel Reviews

Mayflower Hotel

Mayflower Hotel

10/10 Excellent
"Loved it, very charming"
Michael 7-night trip
Posted 8 days ago
Mayflower Hotel

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Frequently asked questions

What is Central San Mateo like?
You'll be sure to have fun exploring San Mateo's Central San Mateo neighbourhood. Are you looking for Central San Mateo travel tips? Make sure that you visit The San Mateo Japanese Garden and Cinemark Century San Mateo 12 while you're in the neighbourhood.
How many hotels will I find in the Central San Mateo area?
Expedia has 45 hotels and other accommodation options in Central San Mateo to choose from, making this an ideal home base for exploring the greater San Mateo area.
If I need to cancel my hotel reservation in Central San Mateo, will I receive a refund?
Yes! The majority of room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within 24 hours of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to get the best deals in Central San Mateo.
What is there to do in this San Mateo neighbourhood?
A few attractions you might want to check out while you're in Central San Mateo are The San Mateo Japanese Garden and Cinemark Century San Mateo 12. While you're out sightseeing, Burlingame Museum of PEZ Memorabilia and Poplar Creek Golf Course are a couple of additional sights to visit in San Mateo.
How can I get around Central San Mateo and the greater San Mateo area?
If you want to venture out of town, San Mateo Station is the closest train station. You can also catch a ride at Hayward Park Station.