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Search Hotels in Central San Mateo, San Francisco

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11 Dec - 12 Dec
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Our top choices for Central San Mateo hotels

Exterior
Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG

Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG

Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG
3.0 star property
Central San Mateo
7.8 out of 10, Good, (1003)
"amazing soaps"
United States
Nickesh
The price is 2.582.986 ₫
2.988.357 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG
House | 3 bedrooms
Sanmateo Cozy Central 3b1b Home Garage Parking AC

Sanmateo Cozy Central 3b1b Home Garage Parking AC

Sanmateo Cozy Central 3b1b Home Garage Parking AC
2.0 star property
Central San Mateo
The price is 7.199.883 ₫
13.422.814 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Sanmateo Cozy Central 3b1b Home Garage Parking AC
Lobby sitting area
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
28.2 km from Central San Mateo
9.0 out of 10, Wonderful, (7183)
"Good location and great hotel to stay, the bed was very comfortable and the breakfast was good with lots of options! "
Canada
Veronica
The price is 3.224.154 ₫
4.879.422 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Hotel Riu Plaza Fisherman's Wharf
Lobby
Hilton San Francisco Financial District

Hilton San Francisco Financial District

Hilton San Francisco Financial District
4.0 star property
26.7 km from Central San Mateo
8.6 out of 10, Excellent, (2116)
"Great stay "
United States
Samantha
The price is 2.463.852 ₫
2.899.830 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hilton San Francisco Financial District
Breakfast, lunch, dinner served; local cuisine
DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport
4.0 star property
3.8 km from Central San Mateo
8.6 out of 10, Excellent, (1357)
"Nice hotel and area "
Canada
Robert
The price is 2.442.240 ₫
2.776.705 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
DoubleTree by Hilton San Francisco Airport
Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds
Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf
4.0 star property
28.3 km from Central San Mateo
9.0 out of 10, Wonderful, (3826)
"We stay here a lot, great place and safe."
United States
Albert
The price is 3.056.797 ₫
4.806.199 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hotel Caza Fisherman's Wharf
Courtyard
Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront
4.0 star property
3.4 km from Central San Mateo
8.6 out of 10, Excellent, (2725)
"Nice airport hotel…staff was great, breakfast was amazing "
United States
Lynne
The price is 2.463.852 ₫
2.801.277 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hilton San Francisco Airport Bayfront
Terrace/patio
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco
4.0 star property
26.6 km from Central San Mateo
8.8 out of 10, Excellent, (2795)
"Clean and comfortable room, good staff, great location. "
United Kingdom
David
The price is 2.640.272 ₫
3.107.468 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Club Quarters Hotel in San Francisco
Property amenity
Holiday Inn Express and Suites Fisherman's Wharf by IHG

Holiday Inn Express and Suites Fisherman's Wharf by IHG

Holiday Inn Express and Suites Fisherman's Wharf by IHG
3.0 star property
28.2 km from Central San Mateo
9.2 out of 10, Wonderful, (2216)
"spotless, breakfast, location, all excellent I will come back!"
United States
Oscar
The price is 3.133.151 ₫
4.477.510 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express and Suites Fisherman's Wharf by IHG
Lobby sitting area
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square
3.5 star property
26.1 km from Central San Mateo
9.4 out of 10, Exceptional, (3058)
"Best location, friendly staff, had a wonderful time stayed! "
United States
Kalinda
The price is 1.996.278 ₫
2.358.805 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Chancellor Hotel on Union Square
Lounge
King George Hotel

King George Hotel

King George Hotel
3.0 star property
25.9 km from Central San Mateo
8.6 out of 10, Excellent, (2101)
"What a wonderful stay completely recommend Daya was amazing"
United States
Glenda
The price is 2.252.996 ₫
3.047.132 ₫ total
includes taxes & fees
18 Dec - 19 Dec
King George Hotel
Courtyard
Hotel Zephyr San Francisco

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco
4.0 star property
28.3 km from Central San Mateo
8.6 out of 10, Excellent, (2322)
"Excellent location."
United States
Rena
The price is 3.737.665 ₫
5.328.722 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Hotel Zephyr San Francisco
Bar (on property)
Hyatt Centric Fisherman's Wharf San Francisco

Hyatt Centric Fisherman's Wharf San Francisco

Hyatt Centric Fisherman's Wharf San Francisco
4.0 star property
28.2 km from Central San Mateo
8.6 out of 10, Excellent, (1464)
"Super location easy walking to all the tourist locations Great food and hospitality services "
United States
Melissa
The price is 3.110.771 ₫
4.745.714 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hyatt Centric Fisherman's Wharf San Francisco
Hypo-allergenic bedding, in-room safe, desk, laptop workspace
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG
3.5 star property
26.6 km from Central San Mateo
9.0 out of 10, Wonderful, (4956)
"Rooms were great, staff was great, location was great. "
United States
Jonathan
The price is 3.133.151 ₫
3.687.563 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Golden Gateway by IHG
Terrace/patio
Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf
4.0 star property
28.2 km from Central San Mateo
9.2 out of 10, Wonderful, (1608)
"Great location and awesome hotel"
United States
Adam
The price is 3.056.797 ₫
4.717.118 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hotel Zoe Fisherman's Wharf
Reception
YOTEL San Francisco

YOTEL San Francisco

YOTEL San Francisco
3.0 star property
25.3 km from Central San Mateo
8.2 out of 10, Very good, (1001)
"My room was clean, the staff is great and the amenities are great as well "
United States
Edwin
The price is 2.235.560 ₫
3.715.635 ₫ total
includes taxes & fees
26 Dec - 27 Dec
YOTEL San Francisco
Balcony
The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay
2.5 star property
19.2 km from Central San Mateo
8.6 out of 10, Excellent, (2285)
"Great place to stay!"
United States
Dixon
The Marina Inn on San Francisco Bay
Building design
Hotel Aluxor SFO

Hotel Aluxor SFO

Hotel Aluxor SFO
2.5 star property
10.1 km from Central San Mateo
8.6 out of 10, Excellent, (2562)
"Clean room, close to airport, quiet. "
Canada
Jana
Hotel Aluxor SFO
Indoor pool
Hotel Nikko San Francisco

Hotel Nikko San Francisco

Hotel Nikko San Francisco
4.5 star property
25.8 km from Central San Mateo
9.4 out of 10, Exceptional, (2634)
"The entire hotel was fabulous!"
United States
Nicole
The price is 4.010.218 ₫
5.931.643 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Nikko San Francisco
Exterior
Handlery Union Square Hotel

Handlery Union Square Hotel

Handlery Union Square Hotel
3.5 star property
26 km from Central San Mateo
8.8 out of 10, Excellent, (2792)
"Clean hotel, great location, kind staff! "
United States
Felix
The price is 29.631.857 ₫
34.875.214 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Handlery Union Square Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Central San Mateo

Find the best Central San Mateo areas for the activities you enjoy most.
Union Square featuring a skyscraper and a city

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

Fisherman\'s Wharf featuring a bay or harbour

Fisherman's Wharf

Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and Hyde Street Pier.

South of Market which includes skyline, a park and cbd

South of Market

Gourmet restaurants great entertainment and top sights from Oracle Park to Chase Center – discover South of Market, a destination also famous for its shopping.

Nob Hill showing street scenes and a city

Nob Hill

Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.

Top Central San Mateo Hotel Reviews

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Frequently asked questions

What is Central San Mateo like?
You'll be sure to have fun exploring San Mateo's Central San Mateo neighbourhood. Are you looking for Central San Mateo travel tips? Make sure that you visit The San Mateo Japanese Garden and Cinemark Century San Mateo 12 while you're in the neighbourhood.
How many hotels will I find in the Central San Mateo area?
Expedia has 45 hotels and other accommodation options in Central San Mateo to choose from, making this an ideal home base for exploring the greater San Mateo area.
If I need to cancel my hotel reservation in Central San Mateo, will I receive a refund?
Yes! The majority of room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within 24 hours of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to get the best deals in Central San Mateo.
What is there to do in this San Mateo neighbourhood?
A few attractions you might want to check out while you're in Central San Mateo are The San Mateo Japanese Garden and Cinemark Century San Mateo 12. While you're out sightseeing, Burlingame Museum of PEZ Memorabilia and Poplar Creek Golf Course are a couple of additional sights to visit in San Mateo.
How can I get around Central San Mateo and the greater San Mateo area?
If you want to venture out of town, San Mateo Station is the closest train station. You can also catch a ride at Hayward Park Station.