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Top Central West End Casino Hotels

AC Hotel St. Louis Central West End

4.0 star property
Central West End
9.0 out of 10, Wonderful, (680)
"Great staff. Rooms were super clean. 10/10 will stay here again"
United States
Jacob
The price is 3.348.355 ₫
3.948.682 ₫ total
includes taxes & fees
26 Dec - 27 Dec
AC Hotel St. Louis Central West End

Aloft St. Louis Cortex

3.0 star property
Central West End
8.6 out of 10, Excellent, (818)
"Great service and beautiful room"
United States
Janyia
The price is 2.890.922 ₫
3.380.326 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Aloft St. Louis Cortex

River City Casino & Hotel

4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1454)
"Awesome place to stay!!"
United States
Kaitlyn
The price is 2.029.841 ₫
2.744.332 ₫ total
includes taxes & fees
7 Dec - 8 Dec
River City Casino & Hotel

Embassy Suites by Hilton St. Louis Downtown

4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1246)
"Great hospitality"
United States
Alejandro
The price is 2.826.328 ₫
3.361.323 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Embassy Suites by Hilton St. Louis Downtown

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1017)
"Love this hotel. "
United States
Lisa
The price is 3.102.633 ₫
3.565.764 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Country Inn & Suites by Radisson, St. Charles Historic District

Best Western Plus St. Louis Airport Hotel

2.5 star property
Woodson Terrace
9.2 out of 10, Wonderful, (1015)
"Love staying here every time I’m in Missouri "
United States
Claudia
The price is 2.890.922 ₫
3.575.823 ₫ total
includes taxes & fees
13 Dec - 14 Dec
Best Western Plus St. Louis Airport Hotel

Ameristar Casino Resort and Spa

4.5 star property
St. Charles
8.4 out of 10, Very good, (1014)
"Yes the room was great & the young lady that assisted me with my check in was very nice & helpful....."
United States
stephany
The price is 3.775.468 ₫
4.849.315 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Ameristar Casino Resort and Spa

Le Méridien St. Louis Clayton

4.0 star property
Clayton
8.8 out of 10, Excellent, (675)
"Small rooms but beautiful lobby. "
United States
Debbie
The price is 3.142.708 ₫
3.700.162 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Le Méridien St. Louis Clayton

Hampton Inn & Suites St. Charles Old Town Area

2.5 star property
St. Charles
9.2 out of 10, Wonderful, (624)
"This was a very nice property. Clean, friendly employees, great breakfast, and a clean, well equipped room. Very comfortable "
United States
Katherine
The price is 2.509.948 ₫
3.041.532 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn & Suites St. Charles Old Town Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Central West End Hotel Reviews

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Frequently asked questions

Searching for casino hotels in Central West End?
Looking to hit the casinos in Central West End? You're in luck, because you'll find Horseshoe St. Louis Casino, Casino Queen, and River City Casino in the area, plus a lot more to see and do. Tourists speak highly of the entertainment venues, spectacular forests and local cuisine. You might want to visit popular sights in the larger area including St. Louis Union Station and Gateway Arch.
How many hotels that are good for gaming will I find in Central West End?
Get your game on at one of Expedia's 136 hotels in Central West End.
What is there to do in Central West End?
You can head to Washington Avenue Historic District, Ballpark Village or Soulard Farmer's Market to shop for the perfect souvenir. Central West End is known for its museums, entertainment venues and theatres, and you can visit cultural spots such as Cathedral Basilica of St. Louis and St. Louis Science Center. Additionally, you might find World Chess Hall of Fame and St. Louis Union Station worth a visit.
What are my transportation options for my casino getaway to Central West End?
Getting around Central West End is easier with these transportation options: You can fly into the closest airport, which is Lambert-St. Louis International Airport (STL), located 9 mi (14.6 km) away. Head over to Central West End Station for metro travel.