Find hotels in Defiance, MO from 1.643.985 ₫

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

Tonight
30 Jun - 1 Jul
Tomorrow
1 Jul - 2 Jul
This weekend
4 Jul - 6 Jul
Next weekend
11 Jul - 13 Jul

Filter by

Guest rating
Guest rating
Property class

Top 10 Defiance hotels and places to stay

Crowne Plaza St. Louis Airport by IHG
Lobby sitting area

Crowne Plaza St. Louis Airport by IHG

3.5 star property
8.0 out of 10, Very good, (1004)
"Great stay "
The price is 3.013.973 ₫
3.581.539 ₫ total
includes taxes & fees
20 Jul - 21 Jul
Crowne Plaza St. Louis Airport by IHG
MainStay Suites St Louis Airport
Property amenity

MainStay Suites St Louis Airport

3.0 star property
8.2 out of 10, Very good, (285)
"Always a safe convenient place to stay "
The price is 2.700.833 ₫
3.217.678 ₫ total
includes taxes & fees
2 Jul - 3 Jul
MainStay Suites St Louis Airport
Comfort Inn St. Louis Airport
Lobby

Comfort Inn St. Louis Airport

3.0 star property
8.6 out of 10, Excellent, (865)
"I had a great stay"
The price is 2.348.550 ₫
2.808.192 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Comfort Inn St. Louis Airport
Embassy Suites by Hilton St. Louis Airport
Lobby

Embassy Suites by Hilton St. Louis Airport

3.5 star property
7.6 out of 10, Good, (1001)
"Breakfast was best "
The price is 3.894.418 ₫
4.605.080 ₫ total
includes taxes & fees
20 Jul - 21 Jul
Embassy Suites by Hilton St. Louis Airport
Extended Stay America Select Suites - St. Louis - Airport - Central
Studio, 2 Double Beds, Non Smoking | Desk, free WiFi, bed sheets

Extended Stay America Select Suites - St. Louis - Airport - Central

2.5 star property
7.0 out of 10, Good, (972)
"Clean and had good accommodation "
The price is 2.183.891 ₫
2.617.068 ₫ total
includes taxes & fees
20 Jul - 21 Jul
Extended Stay America Select Suites - St. Louis - Airport - Central
Hilton St. Louis Frontenac
Lobby

Hilton St. Louis Frontenac

4.0 star property
8.8 out of 10, Excellent, (1002)
"Great service and great location. "
The price is 3.526.739 ₫
4.108.228 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Hilton St. Louis Frontenac
La Quinta Inn & Suites by Wyndham St. Louis Westport
Exterior

La Quinta Inn & Suites by Wyndham St. Louis Westport

3.0 star property
7.2 out of 10, Good, (1007)
"Staff was great. "
The price is 2.419.006 ₫
2.805.758 ₫ total
includes taxes & fees
28 Jul - 29 Jul
La Quinta Inn & Suites by Wyndham St. Louis Westport
Extended Stay America Select Suites - St. Louis - Westport - E Lackland Rd
Studio, 2 Single Beds, Non Smoking | Desk, free WiFi, bed sheets

Extended Stay America Select Suites - St. Louis - Westport - E Lackland Rd

2.5 star property
5.8 out of 10, (1004)
"Unable to locate the person at the front desk to check in for a hour the first room smells do I ask to switch rooms which was much better."
The price is 2.019.518 ₫
2.342.399 ₫ total
includes taxes & fees
1 Jul - 2 Jul
Extended Stay America Select Suites - St. Louis - Westport - E Lackland Rd
Red Roof Inn St Louis - Westport/ Maryland Heights
Exterior

Red Roof Inn St Louis - Westport/ Maryland Heights

2.0 star property
5.4 out of 10, (1002)
"Its a quiet little area. Building is a bit run down on.the outside so dont let the appearance discourage you the room are nice. Newly remodeled and comfortable. "
The price is 1.880.555 ₫
2.181.218 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Red Roof Inn St Louis - Westport/ Maryland Heights
The Lodge Hotel and Banquets
Terrace/patio

The Lodge Hotel and Banquets

2.0 star property
5.0 out of 10, (352)
"Every thing was clean and very nice kept was very wonderful pool "
The price is 2.217.814 ₫
2.656.227 ₫ total
includes taxes & fees
1 Jul - 2 Jul
The Lodge Hotel and Banquets
Courtyard by Marriott St Louis Westport Plaza
Exterior

Courtyard by Marriott St Louis Westport Plaza

3.0 star property
8.8 out of 10, Excellent, (1004)
"The property was clean and the staff was very friendly."
The price is 3.209.685 ₫
3.722.850 ₫ total
includes taxes & fees
20 Jul - 21 Jul
Courtyard by Marriott St Louis Westport Plaza
Residence Inn St Louis Westport
Exterior

Residence Inn St Louis Westport

3.0 star property
9.2 out of 10, Wonderful, (411)
"Loved it "
The price is 4.203.905 ₫
4.876.024 ₫ total
includes taxes & fees
31 Jul - 1 Aug
Residence Inn St Louis Westport
Fairfield Inn & Suites St Louis Westport
Exterior

Fairfield Inn & Suites St Louis Westport

2.5 star property
9.2 out of 10, Wonderful, (781)
"Fairfiled Inn has always been very reliable, clean and comfortable and great breakfast options"
The price is 3.734.195 ₫
4.331.218 ₫ total
includes taxes & fees
5 Jul - 6 Jul
Fairfield Inn & Suites St Louis Westport
Extended Stay America Select Suites St Louis Westport Craig
Lobby

Extended Stay America Select Suites St Louis Westport Craig

2.5 star property
6.4 out of 10, (750)
"Great hotel quiet friendly staff will always come back when im in the area"
The price is 2.042.978 ₫
2.369.687 ₫ total
includes taxes & fees
7 Jul - 8 Jul
Extended Stay America Select Suites St Louis Westport Craig
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
Business centre

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

2.5 star property
4.6 out of 10, (1007)
"Enjoyed staying "
The price is 1.730.359 ₫
2.007.010 ₫ total
includes taxes & fees
27 Jul - 28 Jul
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
Courtyard by Marriott St Louis Creve Coeur
Lobby

Courtyard by Marriott St Louis Creve Coeur

3.0 star property
8.6 out of 10, Excellent, (1003)
"Great place to stay! Lots of options for food and shopping. "
The price is 2.974.830 ₫
3.457.882 ₫ total
includes taxes & fees
27 Jul - 28 Jul
Courtyard by Marriott St Louis Creve Coeur
Comfort Inn St. Louis - Westport Event Center
Lobby

Comfort Inn St. Louis - Westport Event Center

3.0 star property
7.0 out of 10, Good, (1005)
"Plently of dining options close by. Parking was easy. Staff was nice, friendly and helpful. Would stay here again. "
The price is 2.442.492 ₫
2.832.998 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Comfort Inn St. Louis - Westport Event Center
Best Western Plus St. Louis West-Westport
Lobby

Best Western Plus St. Louis West-Westport

2.5 star property
8.0 out of 10, Very good, (1007)
"Clean, quiet, safe"
The price is 2.557.310 ₫
2.966.219 ₫ total
includes taxes & fees
14 Jul - 15 Jul
Best Western Plus St. Louis West-Westport
Hampton Inn St. Louis/Westport
Standard Room, 2 Double Beds, Non Smoking | In-room safe, desk, laptop workspace, iron/ironing board

Hampton Inn St. Louis/Westport

2.5 star property
7.8 out of 10, Good, (947)
"Great communication from staff."
The price is 2.639.509 ₫
3.061.515 ₫ total
includes taxes & fees
20 Jul - 21 Jul
Hampton Inn St. Louis/Westport
Extended Stay America Suites St Louis Westport Central
Terrace/patio

Extended Stay America Suites St Louis Westport Central

2.5 star property
7.4 out of 10, Good, (960)
"Great place "
The price is 2.230.862 ₫
2.587.581 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Extended Stay America Suites St Louis Westport Central
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Defiance

Trip time! Discover the wineries, parks and history in Defiance.

See all hotels in Defiance

Frequently asked questions

What's the weather like in Defiance?

The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.