Find hotels in Defiance, MO from 1.660.148 ₫

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Check prices for these dates

Tonight
28 Jan - 29 Jan
Tomorrow
29 Jan - 30 Jan
This weekend
30 Jan - 1 Feb
Next weekend
6 Feb - 8 Feb

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Our top choices for Defiance hotels

Suite, 1 King Bed, Non Smoking (Upgraded) | In-room safe, laptop workspace, blackout curtains, iron/ironing board

Super 8 by Wyndham St. Clair MO

Super 8 by Wyndham St. Clair MO
2.0 star property
St. Clair
7.2 out of 10, Good, (954 reviews)
"Room was okay, definitely not the best but good for the price. "
United States
Mason
The price is 1.619.382 ₫
1.772.818 ₫ total
includes taxes & fees
6 Feb - 7 Feb
Super 8 by Wyndham St. Clair MO
Lobby

Best Western Plus Washington Hotel

Best Western Plus Washington Hotel
2.5 star property
Washington
9.2 out of 10, Wonderful, (654 reviews)
"Clean room and hotel with a nice breakfast, have stayed here two times while visiting family."
United States
Brooks
The price is 3.363.933 ₫
3.829.838 ₫ total
includes taxes & fees
1 Feb - 2 Feb
Best Western Plus Washington Hotel
Lobby

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
Wentzville
6.4 out of 10, (517 reviews)
"The heating unit was noise, the sink was plumbed backwards but the room was clean."
United States
Gordon
The price is 1.564.620 ₫
1.775.061 ₫ total
includes taxes & fees
30 Jan - 31 Jan
Economy Inn Wentzville
Exterior

Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
Wentzville
9.4 out of 10, Exceptional, (864 reviews)
"Beautiful hotel, friendly staff, good breakfast."
United States
Erika
The price is 3.424.340 ₫
4.084.100 ₫ total
includes taxes & fees
31 Jan - 1 Feb
Holiday Inn Express & Suites Wentzville St Louis West by IHG
Lobby

Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
St. Charles
9.6 out of 10, Exceptional, (1,001 reviews)
"Great hotel "
United States
John Christopher
The price is 2.998.594 ₫
3.476.064 ₫ total
includes taxes & fees
22 Feb - 23 Feb
Drury Plaza Hotel St. Louis St. Charles
Exterior

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very good, (1,012 reviews)
"Great hotel for the money"
United States
Jere
The price is 1.965.728 ₫
2.259.153 ₫ total
includes taxes & fees
8 Feb - 9 Feb
Comfort Suites St Charles - St Louis
Lobby

Quality Inn Near Six Flags St. Louis

Quality Inn Near Six Flags St. Louis
2.5 star property
Pacific
8.4 out of 10, Very good, (365 reviews)
"Excellent staff & very clean room"
United States
Karen
The price is 2.332.588 ₫
2.670.230 ₫ total
includes taxes & fees
22 Feb - 23 Feb
Quality Inn Near Six Flags St. Louis
Exterior

WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon
2.5 star property
St. Peters
9.2 out of 10, Wonderful, (37 reviews)
"Super clean , quiet place "
United States
Phoenix
The price is 2.320.853 ₫
2.747.853 ₫ total
includes taxes & fees
30 Jan - 31 Jan
WoodSpring Suites St Peters-OFallon
Lobby

Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
St. Charles
8.8 out of 10, Excellent, (1,003 reviews)
"My favorite hotel"
United States
Edward
The price is 3.515.307 ₫
4.040.036 ₫ total
includes taxes & fees
4 Feb - 5 Feb
Embassy Suites by Hilton St. Louis St. Charles
Exterior

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
Frontenac
8.8 out of 10, Excellent, (1,001 reviews)
"Great staff"
United States
irene
The price is 3.399.919 ₫
3.960.497 ₫ total
includes taxes & fees
1 Mar - 2 Mar
Hilton St. Louis Frontenac
Room, 2 Queen Beds, Non Smoking | In-room safe, desk, blackout curtains, iron/ironing board

Super 8 by Wyndham Washington

Super 8 by Wyndham Washington
2.0 star property
Washington
8.4 out of 10, Very good, (706 reviews)
"The staff was extremely nice & accommodating."
United States
Brenda
The price is 2.204.810 ₫
2.510.176 ₫ total
includes taxes & fees
8 Feb - 9 Feb
Super 8 by Wyndham Washington
Free daily buffet breakfast

Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area
2.5 star property
St. Charles
9.2 out of 10, Wonderful, (644 reviews)
"The breakfast was delicious and contained a wide variety. The staff friendly and the rooms very clean. "
United States
Kim
The price is 2.922.713 ₫
3.518.914 ₫ total
includes taxes & fees
22 Feb - 23 Feb
Hampton Inn & Suites St. Charles Old Town Area
Lobby lounge

Fairfield Inn & Suites Wentzville

Fairfield Inn & Suites Wentzville
2.5 star property
Wentzville
9.0 out of 10, Wonderful, (650 reviews)
"Hotel staff was friendly and room was very clean "
United States
Danielle
The price is 3.334.727 ₫
3.816.594 ₫ total
includes taxes & fees
2 Feb - 3 Feb
Fairfield Inn & Suites Wentzville
Exterior

Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG
2.5 star property
St. Peters
9.2 out of 10, Wonderful, (385 reviews)
"Parking was easy and the room was nice."
United States
Martha
The price is 2.633.777 ₫
3.184.250 ₫ total
includes taxes & fees
3 Feb - 4 Feb
Holiday Inn Express & Suites St Peters by IHG
Lobby sitting area

Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel
3.0 star property
St. Charles
8.2 out of 10, Very good, (1,000 reviews)
"Very nice at service desk, room clean and comfortable, breakfast really good. Would recommend, would stay again!"
United States
Melisa
The price is 2.305.207 ₫
2.672.358 ₫ total
includes taxes & fees
4 Feb - 5 Feb
Best Western Plus The Charles Hotel
Lobby

Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles
2.0 star property
St. Peters
6.2 out of 10, (1,001 reviews)
"The staff was kind and the room was great EXCEPT the room is infested with roaches and water bugs and small bugs possibly bed bugs? They end up crawling in your bags and clothes and I have a pretty thick skin and can deal with a lot but this was really bad and I wouldn't do it again"
United States
Jeremy
The price is 1.444.235 ₫
1.660.148 ₫ total
includes taxes & fees
11 Feb - 12 Feb
Days Inn by Wyndham St Peters/St Charles
Lobby

Quality Inn Foristell

Quality Inn Foristell
2.5 star property
Foristell
8.2 out of 10, Very good, (928 reviews)
" Clean room friendly staff easy access"
United States
Steve
The price is 1.928.394 ₫
2.178.121 ₫ total
includes taxes & fees
3 Feb - 4 Feb
Quality Inn Foristell
Exterior

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1,000 reviews)
"Wonderful place staff awesome "
United States
Chad
The price is 2.917.224 ₫
3.352.678 ₫ total
includes taxes & fees
8 Feb - 9 Feb
Country Inn & Suites by Radisson, St. Charles Historic District
Family Studio Suite (No Elevator Access) | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds

River Sirens Hotel

River Sirens Hotel
2.5 star property
Washington
9.8 out of 10, Exceptional, (186 reviews)
"Great place"
United States
Herchel
River Sirens Hotel
Suite, 2 Bedrooms | Premium bedding, down duvets, pillow-top beds, in-room safe

Candlewood Suites St Louis St Charles by IHG

Candlewood Suites St Louis St Charles by IHG
2.5 star property
St. Charles
7.6 out of 10, Good, (766 reviews)
"The staff was very professional and the room was clean. I will definitely book here again"
United States
Ngozi
The price is 1.986.640 ₫
2.283.185 ₫ total
includes taxes & fees
1 Feb - 2 Feb
Candlewood Suites St Louis St Charles by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

Missouri wineries have some of the most superb wine we've ever tasted! We recommend sipping on some chambourcin while basking in the sunshine.
Photo by Pages of Travel
Open Photo by Pages of Travel

Chandler Hill Vineyards

This elegant Missouri winery showcases local and California wines from its hillside setting. Savour varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen.
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Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri

August A. Busch Memorial Conservation Area

This sprawling conservation area features over 30 lakes and historic WWII bunkers amid diverse habitats. Explore well-maintained trails while watching for migratory birds and wildlife in their natural environment.
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Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

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A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

Top Defiance Hotel Reviews

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

10/10 Excellent
"No complaints "
Matthew 6-night trip
Posted 3 days ago
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

More cheap stays in Defiance

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

1310 Bass Pro Drive St. Charles MO
The price is 1.438.407 ₫ per night from 1 Mar to 2 Mar
1.438.407 ₫
1.667.502 ₫ total
1 Mar - 2 Mar
includes taxes & fees
5.6/10 (1,007 reviews)

Hotels in Defiance with star rating

Frequently asked questions

What's the weather like in Defiance?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.