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Check availability on Downtown Louisville Spa Hotels

Our top choices for Downtown Louisville hotels with a spa

4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3838)
"Beautiful room and great hospitality. "
United States
Chase
The price is 3.514.055 ₫
4.134.636 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Galt House Hotel Trademark Collection by Wyndham
Sauna, body treatments, aromatherapy, hot stone massages
Omni Louisville Hotel

Omni Louisville Hotel

4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1718)
"Clean room, friendly staff"
United States
Jill
The price is 4.407.938 ₫
5.186.380 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Omni Louisville Hotel
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1000)
" Loved our stay, would definitely plan to come back if we are ever in the area again."
United States
Erica
The price is 3.664.318 ₫
4.443.579 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
21c Museum Hotel Louisville
Full-sized fridge, microwave, oven, stovetop
The Reserve on Main

The Reserve on Main

4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
The price is 3.796.128 ₫
5.724.245 ₫ total
includes taxes & fees
14 Dec - 15 Dec
The Reserve on Main
Indoor pool
Caesars Southern Indiana - A Caesars Rewards Destination

Caesars Southern Indiana - A Caesars Rewards Destination

3.5 star property
Elizabeth
8.2 out of 10, Very good, (1009)
"The room was very clean, the staff was very friendly and helpful."
United States
Judy
The price is 1.877.028 ₫
2.610.741 ₫ total
includes taxes & fees
11 Dec - 12 Dec
Caesars Southern Indiana - A Caesars Rewards Destination
Exterior detail
Central Park Bed & Breakfast

Central Park Bed & Breakfast

4.0 star property
Old Louisville
9.4 out of 10, Exceptional, (56)
"The room was beautiful, breakfast was delicious and the park across the street was lovely. I especially enjoyed having coffee on the back veranda."
United States
Cher
The price is 3.574.160 ₫
4.148.588 ₫ total
includes taxes & fees
11 Dec - 12 Dec
Central Park Bed & Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Downtown Louisville Hotel Reviews

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Frequently asked questions

Looking for a spa hotel in Downtown Louisville?
Forget the stress of everyday life and book yourself a hotel with a spa. Travellers love the restaurants and bars in Downtown Louisville. Enjoy the live music and riverfront during your holiday. Hotels with spas are the perfect way to break out of your routine and add a layer of luxury to your weekend away.
How many spa hotels will I find in Downtown Louisville?
Among Expedia's 370 accommodation options in Downtown Louisville, there are 3 spa hotels.
What's there to see and do in Downtown Louisville?
Take in the sights and attractions that Downtown Louisville offers with a visit to Whiskey Row, KFC Yum Center and Fourth Street Live!. If you have a little extra time during your trip, you might want to check out Belle of Louisville and Louisville Palace.
What is a Downtown Louisville spa hotel?
Spa hotels in Downtown Louisville provide lodging and have an on-site spa offering services such as couples massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on holiday.