The Best Hotels Closest to 21c Museum Hotel in Louisville - 2026 Updated Prices

Q: What's the area like around 21c Museum Hotel?

21c Museum Hotel is located in a family-friendly area of Louisville known for its stunning river views and great live music scene. If you're looking for a convenient place to stay, take a look at the 250 hotels and other accommodation options you'll find within a mile.

Q: How many hotels are there near 21c Museum Hotel?

Expedia has 250 hotels and other accommodation options within a mile from 21c Museum Hotel.

Q: If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?

Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best deals available near 21c Museum Hotel.

Q: What can I see and do near 21c Museum Hotel?

You might want to spend some time browsing the exhibits at Louisville Science Center, Muhammad Ali Center or Louisville Slugger Museum. Explore landmarks like Belle of Louisville, Whiskey Row and Union Station. You can watch performances at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall if you're interested in local theatre.

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Our top choices for 21c Museum Hotel hotels

1. Louisville Bourbon Inn

Old Louisville, 2.8 km from 21c Museum Hotel

Roy

8.515.573 ₫ total

includes taxes & fees

4 Aug - 5 Aug

2. Market Street Inn

2.1 km from 21c Museum Hotel

Anissa

4.954.429 ₫ total

includes taxes & fees

4 Aug - 5 Aug

3. Stellar Suites

East Market District, 2.2 km from 21c Museum Hotel

Brad

4.444.236 ₫ total

includes taxes & fees

8 Aug - 9 Aug

4. DuPont Mansion Bed & Breakfast

Old Louisville, 2.8 km from 21c Museum Hotel

Casey

4.264.685 ₫ total

includes taxes & fees

5 Aug - 6 Aug

5. Hotel Distil, Autograph Collection

Downtown Louisville, 0.8 km from 21c Museum Hotel

Jasmine

6.779.856 ₫ total

includes taxes & fees

16 Aug - 17 Aug

6. Homewood Suites by Hilton Louisville Downtown, KY

Downtown Louisville, 0.1 km from 21c Museum Hotel

Torrence

3.526.525 ₫ total

includes taxes & fees

30 Aug - 31 Aug

7. The Brown Hotel

Downtown Louisville, 1.2 km from 21c Museum Hotel

Anthony

3.943.588 ₫ total

includes taxes & fees

14 Aug - 15 Aug

8. The Grady

Downtown Louisville, 0.1 km from 21c Museum Hotel

Jennifer

4.945.364 ₫ total

includes taxes & fees

19 Aug - 20 Aug

2 restaurants; breakfast and dinner served

9. Tempo By Hilton Louisville Downtown Nulu

Phoenix Hill, 2 km from 21c Museum Hotel

Jennifer

3.780.233 ₫ total

includes taxes & fees

6 Aug - 7 Aug

3 bars/lounges, cocktail bar, lobby lounge

10. Omni Louisville Hotel

Downtown Louisville, 0.8 km from 21c Museum Hotel

Heriberto

4.925.628 ₫ total

includes taxes & fees

9 Aug - 10 Aug

11. 21c Museum Hotel Louisville

Downtown Louisville, < 0.1 km from 21c Museum Hotel

nicolle

4.838.980 ₫ total

includes taxes & fees

27 Aug - 28 Aug

12. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Downtown Louisville, 0.8 km from 21c Museum Hotel

Kristen

5.378.587 ₫ total

includes taxes & fees

23 Aug - 24 Aug

13. Towneplace Suites By Marriott Louisville Downtown

Downtown Louisville, 0.3 km from 21c Museum Hotel

Michael

3.001.169 ₫ total

includes taxes & fees

27 Aug - 28 Aug

14. Cambria Hotel Louisville Downtown-Whiskey Row

Downtown Louisville, 1.2 km from 21c Museum Hotel

Kerry

3.488.779 ₫ total

includes taxes & fees

16 Aug - 17 Aug

15. Moxy Louisville Downtown

Downtown Louisville, 0.9 km from 21c Museum Hotel

Zacarias

2.970.227 ₫ total

includes taxes & fees

16 Aug - 17 Aug

16. AC Hotel Louisville Downtown

East Market District, 2 km from 21c Museum Hotel

David

3.763.372 ₫ total

includes taxes & fees

14 Aug - 15 Aug

17. Hotel Genevieve part of JdV by Hyatt

East Market District, 2 km from 21c Museum Hotel

Christina

4.176.882 ₫ total

includes taxes & fees

10 Aug - 11 Aug

18. Central Park Bed & Breakfast

Old Louisville, 2.9 km from 21c Museum Hotel

Candace Faye

4.011.718 ₫ total

includes taxes & fees

5 Aug - 6 Aug

4 restaurants; breakfast, lunch and dinner served

19. Galt House Hotel Trademark Collection by Wyndham

Downtown Louisville, 0.5 km from 21c Museum Hotel

marcus

4.515.982 ₫ total

includes taxes & fees

16 Aug - 17 Aug

20. Aloft by Marriott Louisville Downtown

Downtown Louisville, 0.9 km from 21c Museum Hotel

Margarita

3.897.067 ₫ total

includes taxes & fees

16 Aug - 17 Aug

View all properties

Compare popular hotels close to 21c Museum Hotel

Property	Property class	Guest rating
Louisville Bourbon Inn	5.0 star property	10.0 Exceptional 24 reviews	View
Market Street Inn	3.5 star property	9.8 Exceptional 122 reviews	View
Stellar Suites	4.5 star property	9.6 Exceptional 145 reviews	View
DuPont Mansion Bed & Breakfast	2.0 star property	9.6 Exceptional 143 reviews	View
Hotel Distil, Autograph Collection	4.0 star property	9.6 Exceptional 489 reviews	View

Top 21c Museum Hotel Hotel Reviews

Econo Lodge Louisville Downtown

8/10 Good

"Price was great!"

Holiday Inn Express & Suites Louisville Downtown by IHG

8/10 Good

"Staff was great, property is clean. Rooms are spacious and comfy beds. Breakfast was your typical hotel breakfast with hot and cold foods (eggs, sausages, potatotoes, cereal, oatmeal, toast, bagels, fruits and cinnamon rolls). There was only 1 working elevator and being in downtown, there were times you had a long wait for the elevator. There were 5 of us but room only had 3 towels. Also the hand soap was empty. Those issues were resolved fairly quickly. There is a $22 parking fee for each day. But it includeds in and out privlidges. Which was great. When we checked out we left our car in the parking garage while we explored downtown louisville. Great stay!!"

Homewood Suites by Hilton Louisville Downtown, KY

8/10 Good

"If you’re looking for a family hotel this is for you. If you are a couple looking for a place, this isn’t it. We picked this hotel because it had a pool and the location seemed like there were restaurants around to choose from. The breakfast was free but not great and the coffee was terrible. Plus the amount of people you had to deal with to get breakfast… not worth it. We got in the car and drove to Starbucks. The pool was so small and next to a window where anyone walking in the street would see you. Plus it was full of kids. Most of the restaurants were closed down and the homelessness and drug addicts made it feel uncomfortable to walk to Whiskey row or the casino. The rooms are huge, super clean and comfortable but we did have a kid running back and forth on the floor above. We called the front office and they went up there immediately and it was stopped. The employees and the hotel were very nice. I would just not stay here again based on the location and the amenities!"

Other attractions near 21c Museum Hotel

A historic building with ornate architecture, including columns and decorative moldings.

Louisville Science Center

7.8/10 (6 reviews)

You can spend an afternoon browsing the exhibits at Louisville Science Center in Louisville. Stroll along the area's riverfront or experience its acclaimed art galleries.

See properties

Frequently asked questions

What's the area like around 21c Museum Hotel?

21c Museum Hotel is located in a family-friendly area of Louisville known for its stunning river views and great live music scene. If you're looking for a convenient place to stay, take a look at the 250 hotels and other accommodation options you'll find within a mile.

How many hotels are there near 21c Museum Hotel?

Expedia has 250 hotels and other accommodation options within a mile from 21c Museum Hotel.

If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?

Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best deals available near 21c Museum Hotel.

What can I see and do near 21c Museum Hotel?

You might want to spend some time browsing the exhibits at Louisville Science Center, Muhammad Ali Center or Louisville Slugger Museum. Explore landmarks like Belle of Louisville, Whiskey Row and Union Station. You can watch performances at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall if you're interested in local theatre.

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Our top choices for 21c Museum Hotel hotels

1. Louisville Bourbon Inn

2. Market Street Inn

3. Stellar Suites

4. DuPont Mansion Bed & Breakfast

5. Hotel Distil, Autograph Collection

6. Homewood Suites by Hilton Louisville Downtown, KY

7. The Brown Hotel

8. The Grady

9. Tempo By Hilton Louisville Downtown Nulu

10. Omni Louisville Hotel

11. 21c Museum Hotel Louisville

12. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

13. Towneplace Suites By Marriott Louisville Downtown

14. Cambria Hotel Louisville Downtown-Whiskey Row

15. Moxy Louisville Downtown

16. AC Hotel Louisville Downtown

17. Hotel Genevieve part of JdV by Hyatt

18. Central Park Bed & Breakfast

19. Galt House Hotel Trademark Collection by Wyndham

20. Aloft by Marriott Louisville Downtown

Compare popular hotels close to 21c Museum Hotel

Top 21c Museum Hotel Hotel Reviews

Econo Lodge Louisville Downtown

Other attractions near 21c Museum Hotel

Louisville Science Center

Frequently asked questions

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