Photo by Jw

Search Hotels in Downtown Palo Alto, Palo Alto

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
15 Dec - 16 Dec
Tomorrow
16 Dec - 17 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Downtown Palo Alto hotels

Interior
The Cardinal Hotel

The Cardinal Hotel

The Cardinal Hotel
2.5 star property
Downtown Palo Alto
9.0 out of 10, Wonderful, (377)
"A fantastic hotel, and a great location."
United States
Michael
The price is 3.814.515 ₫
4.413.204 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
The Cardinal Hotel
Front of property
Hotel Keen

Hotel Keen

Hotel Keen
3.0 star property
Downtown Palo Alto
8.0 out of 10, Very good, (690)
"Great place to visit "
United States
Ernest
The price is 3.253.387 ₫
3.757.662 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Hotel Keen
Exterior
Graduate by Hilton Palo Alto

Graduate by Hilton Palo Alto

Graduate by Hilton Palo Alto
4.0 star property
Downtown Palo Alto
9.2 out of 10, Wonderful, (261)
"Great hotel especially if affiliated with Stanford."
United States
Kathleen E
The price is 4.832.070 ₫
6.369.939 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Graduate by Hilton Palo Alto
Breakfast, lunch, dinner served; Japanese cuisine, al fresco dining
Nobu Hotel Palo Alto

Nobu Hotel Palo Alto

Nobu Hotel Palo Alto
5.0 star property
Downtown Palo Alto
9.2 out of 10, Wonderful, (434)
"Beautiful hotel. "
United States
Dianne
The price is 10.391.265 ₫
12.022.174 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Nobu Hotel Palo Alto
Outdoor wedding area
el PRADO

el PRADO

el PRADO
4.0 star property
Downtown Palo Alto
9.4 out of 10, Exceptional, (609)
"Great stay - big, well appointed rooms in an excellent location "
Hong Kong SAR China
David
el PRADO
Courtyard
Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront
4.0 star property
22.7 km from Downtown Palo Alto
8.6 out of 10, Excellent, (2738)
"Nice airport hotel…staff was great, breakfast was amazing "
United States
Lynne
The price is 2.459.178 ₫
2.795.962 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Hilton San Francisco Airport Bayfront
Building design
Hotel Aluxor SFO

Hotel Aluxor SFO

Hotel Aluxor SFO
2.5 star property
29.7 km from Downtown Palo Alto
8.6 out of 10, Excellent, (2574)
"Very clean, great staff, easy access."
United States
Nicole
Hotel Aluxor SFO
Exterior
The Westin San Francisco Airport

The Westin San Francisco Airport

The Westin San Francisco Airport
4.0 star property
25.9 km from Downtown Palo Alto
8.8 out of 10, Excellent, (2035)
"Room great, location and shuttle were excellent Enjoyed 2 restaurants and Starbucks on site. "
United States
Robert
The price is 2.707.516 ₫
3.882.210 ₫ total
includes taxes & fees
23 Dec - 24 Dec
The Westin San Francisco Airport
Executive lounge
Hilton Garden Inn Sunnyvale

Hilton Garden Inn Sunnyvale

Hilton Garden Inn Sunnyvale
3.0 star property
12.9 km from Downtown Palo Alto
8.8 out of 10, Excellent, (796)
"Nice staff and great room!"
United States
Jhen
The price is 1.873.058 ₫
2.110.843 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hilton Garden Inn Sunnyvale
Exterior
Half Moon Bay Lodge

Half Moon Bay Lodge

Half Moon Bay Lodge
3.0 star property
23.7 km from Downtown Palo Alto
9.0 out of 10, Wonderful, (1081)
"Always great staff here, nice rooms, nice jacuzzi "
United States
Pamela
The price is 3.089.758 ₫
3.635.034 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Half Moon Bay Lodge
Premium bedding, in-room safe, desk, blackout curtains
Maple Tree Inn

Maple Tree Inn

Maple Tree Inn
3.0 star property
15.6 km from Downtown Palo Alto
9.0 out of 10, Wonderful, (2480)
"Great room and beds, breakfast was amazing "
United States
Donald
The price is 2.133.761 ₫
2.411.037 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Maple Tree Inn
Breakfast, lunch, dinner served; local cuisine
DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport
4.0 star property
23.3 km from Downtown Palo Alto
8.6 out of 10, Excellent, (1363)
"Nice hotel and area "
Canada
Robert
The price is 2.523.894 ₫
2.869.542 ₫ total
includes taxes & fees
23 Dec - 24 Dec
DoubleTree by Hilton San Francisco Airport
Property grounds
Creekside Inn

Creekside Inn

Creekside Inn
3.5 star property
Barron Park, 3.7 km from Downtown Palo Alto
9.0 out of 10, Wonderful, (1640)
"Excellent beautiful and clean and safe wonderful location. "
United States
Debra
The price is 2.236.095 ₫
3.043.063 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Creekside Inn
Bar (on property)
The Domain Hotel

The Domain Hotel

The Domain Hotel
4.0 star property
17.4 km from Downtown Palo Alto
8.2 out of 10, Very good, (1410)
"Clean room, buffet breakfast had lots of options, n location was perfect."
United States
Michelle
The price is 2.580.717 ₫
2.908.339 ₫ total
includes taxes & fees
18 Dec - 19 Dec
The Domain Hotel
Poolside bar
Shashi Hotel Mountain View Palo Alto

Shashi Hotel Mountain View Palo Alto

Shashi Hotel Mountain View Palo Alto
5.0 star property
8 km from Downtown Palo Alto
9.4 out of 10, Exceptional, (1192)
"Perfect place to stay and enjoy "
United States
Ali
The price is 3.527.769 ₫
3.887.424 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Shashi Hotel Mountain View Palo Alto
Exterior
Hilton Garden Inn Cupertino

Hilton Garden Inn Cupertino

Hilton Garden Inn Cupertino
3.0 star property
18 km from Downtown Palo Alto
8.8 out of 10, Excellent, (1007)
"Great place to stay"
United States
Alexander
The price is 2.410.510 ₫
2.699.772 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Hilton Garden Inn Cupertino
Two Queens Deluxe Room | Desk, blackout curtains, soundproofing, free WiFi
Good Nite Inn - Redwood City

Good Nite Inn - Redwood City

Good Nite Inn - Redwood City
2.5 star property
8.7 km from Downtown Palo Alto
8.6 out of 10, Excellent, (1515)
"Just a nice stay"
United States
Francisco
The price is 2.236.095 ₫
2.525.735 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Good Nite Inn - Redwood City
Exterior
Aloft San Francisco Airport

Aloft San Francisco Airport

Aloft San Francisco Airport
3.0 star property
25.9 km from Downtown Palo Alto
9.0 out of 10, Wonderful, (2242)
"All good, friendly staff, spotless room. "
United States
Michael
The price is 2.870.883 ₫
3.299.937 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Aloft San Francisco Airport
Lobby
Best Western Inn & Suites San Mateo - San Francisco Airport

Best Western Inn & Suites San Mateo - San Francisco Airport

Best Western Inn & Suites San Mateo - San Francisco Airport
2.5 star property
20.8 km from Downtown Palo Alto
8.8 out of 10, Excellent, (1260)
"Staff was great and check in was perfect."
United States
FLORENCE CARMELA
The price is 2.485.748 ₫
2.857.242 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Best Western Inn & Suites San Mateo - San Francisco Airport
Lobby
Hotel 1550

Hotel 1550

Hotel 1550
3.5 star property
28.3 km from Downtown Palo Alto
9.0 out of 10, Wonderful, (1044)
"Great front desk experience, nice room and very convenient to the airport. "
United States
Elmaz
The price is 2.670.686 ₫
3.160.536 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hotel 1550
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Downtown Palo Alto

Find the best Downtown Palo Alto areas for the activities you enjoy most.

Stanford

You'll enjoy the churches and monuments in Stanford. You might want to make time for a stop at Stanford Stadium or Stanford Shopping Center.

East Palo Alto

You'll enjoy the mountain views and restaurants in East Palo Alto. You might want to make time for a stop at San Francisco Bay or Silicon Valley.

Barron Park

While Barron Park may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like San Antonio Shopping Center and Stanford Maples Pavillion.

University South

While visiting University South, you might make a stop by sights like Museum of American Heritage and Hewlett Packard House and Garage.

Old Palo Alto

When in Old Palo Alto, you can plan a visit to Stanford Stadium and Palo Alto Junior Museum and Zoo, some noteworthy sights in the nearby area.

Top Downtown Palo Alto Hotel Reviews

The Domain Hotel

The Domain Hotel

10/10 Excellent
"very comfortable and clean "
Ashley 5-night trip
Posted 3 days ago
The Domain Hotel

Explore a world of travel with Expedia

Frequently asked questions

What is Downtown Palo Alto like?
Travellers will be sure to enjoy their time in Palo Alto's Downtown Palo Alto neighbourhood. Make sure that you visit Downtown Palo Alto Farmers' Market and Stanford Theatre as part of your Downtown Palo Alto travel plans.
How many hotels can I expect to find in Downtown Palo Alto?
With 13 Expedia hotels and other accommodation options in Downtown Palo Alto to choose from, this is a good starting point for exploring the greater Palo Alto area.
If I need to cancel my hotel reservation in Downtown Palo Alto, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then filter by "fully refundable" to get the best deals available in Downtown Palo Alto.
What are the top things to see and do in Downtown Palo Alto?
A few attractions you might want to check out while you're in Downtown Palo Alto are Downtown Palo Alto Farmers' Market and Stanford Theatre. Museum of American Heritage and Hewlett Packard House and Garage are also worth a visit when you're out sightseeing in Palo Alto.