Search Hotels in Downtown South San Francisco, San Francisco

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Downtown South San Francisco hotels

Miller Apartments

Miller Apartments
2.0 star property
Downtown South San Francisco
7.4 out of 10, Good, (15 reviews)
"Own bedroom was quiet and tidy, shared bathroom clean and tidy, good communication "
Australia
Kasey
The price is 1.486.334 ₫
3.726.339 ₫ total
includes taxes & fees
13 Mar - 14 Mar
Miller Apartments

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
Downtown South San Francisco
8.0 out of 10, Very good, (2,013 reviews)
"Pleasant stay "
United States
Alok
The price is 2.814.267 ₫
3.301.443 ₫ total
includes taxes & fees
13 Mar - 14 Mar
La Quinta Inn & Suites by Wyndham San Francisco Airport N

Airport Inn

Airport Inn
2.0 star property
Downtown South San Francisco
8.8 out of 10, Excellent, (991 reviews)
"Very clean room, friendly staff and secure parking."
United States
Christopher
The price is 2.713.149 ₫
3.178.972 ₫ total
includes taxes & fees
13 Mar - 14 Mar
Airport Inn

Inn By The SFO

Inn By The SFO
2.0 star property
Downtown South San Francisco
7.8 out of 10, Good, (1,004 reviews)
"Everything great. Good location close to airport and walking distance to coffee, market, and restaurants. Try shabu shack!"
United States
Gabriel
Inn By The SFO

Pacifica Beach Hotel

Pacifica Beach Hotel
2.5 star property
9.7 km from Downtown South San Francisco
8.0 out of 10, Very good, (1,013 reviews)
"Easy check-in, courteous staff, across the street from beach, 3 blocks from stores & restaurants."
United States
Constance
The price is 3.104.628 ₫
3.609.146 ₫ total
includes taxes & fees
11 Mar - 12 Mar
Pacifica Beach Hotel

Inn at Rockaway San Francisco Pacifica

Inn at Rockaway San Francisco Pacifica
2.5 star property
8.8 km from Downtown South San Francisco
8.2 out of 10, Very good, (1,014 reviews)
"Clean and comfortable room with access to the beach and dining options."
United States
Brad
Inn at Rockaway San Francisco Pacifica

The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay
3.5 star property
20.5 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2,350 reviews)
"staff was amazing hotel could use a renovation but was still perfect for what we needed"
United States
ethan
The Marina Inn on San Francisco Bay

Harbor View Inn

Harbor View Inn
2.0 star property
17.7 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (652 reviews)
"Lovely location, excellent staff."
United States
Bryn
The price is 2.976.133 ₫
3.739.743 ₫ total
includes taxes & fees
12 Mar - 13 Mar
Harbor View Inn

Half Moon Bay Lodge

Half Moon Bay Lodge
3.0 star property
24.9 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,174 reviews)
"It was very clean, easily accessible, and great for a little getaway"
United States
Samantha
The price is 3.291.982 ₫
3.869.442 ₫ total
includes taxes & fees
12 Mar - 13 Mar
Half Moon Bay Lodge

Hampton Inn Oakland Downtown-City Center

Hampton Inn Oakland Downtown-City Center
2.5 star property
20.6 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,015 reviews)
"Great staff,nice room,decent breakfast just overall a great place to stay very pleased "
United States
jerel chester
The price is 3.232.071 ₫
3.755.505 ₫ total
includes taxes & fees
29 Mar - 30 Mar
Hampton Inn Oakland Downtown-City Center

Aloft San Francisco Airport

Aloft San Francisco Airport
3.0 star property
6.9 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (2,269 reviews)
"Great place! "
United States
Jon
The price is 2.982.965 ₫
3.428.769 ₫ total
includes taxes & fees
20 Mar - 21 Mar
Aloft San Francisco Airport

La Quinta Inn & Suites by Wyndham Oakland - Hayward

La Quinta Inn & Suites by Wyndham Oakland - Hayward
3.0 star property
26.3 km from Downtown South San Francisco
8.4 out of 10, Very good, (1,184 reviews)
"Will stay again"
United States
Benedict
The price is 2.173.371 ₫
2.525.349 ₫ total
includes taxes & fees
29 Mar - 30 Mar
La Quinta Inn & Suites by Wyndham Oakland - Hayward

Stanyan Park Hotel

Stanyan Park Hotel
3.0 star property
12.8 km from Downtown South San Francisco
9.4 out of 10, Exceptional, (1,009 reviews)
"Perfect locatuon, cute clean hotel"
United States
Lori
The price is 6.714.036 ₫
7.809.263 ₫ total
includes taxes & fees
16 Mar - 17 Mar
Stanyan Park Hotel

Executive Inn & Suites Embarcadero Cove

Executive Inn & Suites Embarcadero Cove
3.0 star property
20.7 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,000 reviews)
"I always stay here when in Oakland. Beautiful location on the estuary. View of San Francisco. Clean, nicely appointed lobby and rooms."
United States
Linda
The price is 3.774.691 ₫
4.386.002 ₫ total
includes taxes & fees
28 Mar - 29 Mar
Executive Inn & Suites Embarcadero Cove

Hotel Nova SFO

Hotel Nova SFO
2.5 star property
1.9 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1,006 reviews)
"Everything was a okay, great stay"
United States
Jesus
The price is 2.601.423 ₫
3.050.760 ₫ total
includes taxes & fees
29 Mar - 30 Mar
Hotel Nova SFO

Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point
3.5 star property
The East Side, 1.4 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1,316 reviews)
"It was a nice room with a great breakfast 😋 "
United States
Joshua Joseph
The price is 3.419.426 ₫
4.021.798 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Embassy Suites by Hilton San Francisco Airport Oyster Point

Best Western Inn & Suites San Mateo - San Francisco Airport

Best Western Inn & Suites San Mateo - San Francisco Airport
2.5 star property
11.8 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,348 reviews)
"The staff is friendly, the room was clean, and the breakfast was wonderful. Would stay there again."
United States
Steven
The price is 2.417.221 ₫
2.778.530 ₫ total
includes taxes & fees
15 Mar - 16 Mar
Best Western Inn & Suites San Mateo - San Francisco Airport

Hampton Inn & Suites San Mateo-San Francisco Airport

Hampton Inn & Suites San Mateo-San Francisco Airport
3.0 star property
17 km from Downtown South San Francisco
9.4 out of 10, Exceptional, (919 reviews)
"Breakfast served every morning and staff was extremely friendly."
United States
Richard
The price is 3.014.760 ₫
3.465.316 ₫ total
includes taxes & fees
3 Apr - 4 Apr
Hampton Inn & Suites San Mateo-San Francisco Airport

DoubleTree by Hilton San Francisco South Airport Blvd

DoubleTree by Hilton San Francisco South Airport Blvd
4.0 star property
1.5 km from Downtown South San Francisco
8.4 out of 10, Very good, (2,165 reviews)
"Clean room, safe, excellent service"
United States
Nathan
The price is 2.731.494 ₫
3.225.895 ₫ total
includes taxes & fees
27 Mar - 28 Mar
DoubleTree by Hilton San Francisco South Airport Blvd

Sonesta Select San Francisco Airport Oyster Point Waterfront

Sonesta Select San Francisco Airport Oyster Point Waterfront
3.0 star property
Oyster Point, 2.2 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1,992 reviews)
"I love this hotel :)"
United States
Daniel
The price is 2.680.254 ₫
3.200.802 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Sonesta Select San Francisco Airport Oyster Point Waterfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas for the activities you enjoy most.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

Fisherman's Wharf

Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and Ghirardelli Square.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Warfield Theatre are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

South of Market

Gourmet restaurants great entertainment and top sights from Oracle Park to SOMA Pilipinas – discover South of Market, a destination also famous for its shopping.

Nob Hill

Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.

Top Downtown South San Francisco Hotel Reviews

Frequently asked questions

What's it like in Downtown South San Francisco?
You'll be sure to have fun exploring South San Francisco's Downtown South San Francisco neighbourhood.
How many hotels should I expect to find in the Downtown South San Francisco area?
When you want to put your feet up after a day of exploring the sights in South San Francisco, you can choose from 14 Expedia hotels and other accommodation options in Downtown South San Francisco.
If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Downtown South San Francisco.
What can I see and do in this South San Francisco neighbourhood?
South San Francisco Hillside Sign, Sign Hill Park and See's Candies are just a few of the places to visit in and around Downtown South San Francisco. Cinemark Century at Tanforan and K1 Speed are also worth a visit when you're out sightseeing in South San Francisco.