Downtown Holidays
Book a Hotel + Flight or Car together to unlock savings
Where to stay in Downtown
Find the best Downtown areas and neighborhoods for the activities you enjoy most. Learn more about Downtown
Serenity Bay
When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.
Top hotels in Downtown
Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
Fully refundable
The price is 2.224.511 ₫ per night from 21 Jun to 22 Jun
2.224.511 ₫
2.612.584 ₫ total
21 Jun - 22 Jun
includes taxes & fees
8/10 Very Good! (713 reviews)
"Room was easy access to the parking bathroom was accessible for person with limited walking ability staff was very friendly and helpful the pool was not open"
Reviewed on 9 Jun 2026
Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
Fully refundableReserve now, pay when you stay
The price is 1.587.809 ₫ per night from 18 Jun to 19 Jun
1.587.809 ₫
1.762.467 ₫ total
18 Jun - 19 Jun
includes taxes & fees
8/10 Very Good! (1,017 reviews)
"The room was clean… but very musky smelling. Not like the pictures. Okay for the price."
Reviewed on 13 Jun 2026
The Shepherd Hotel Downtown Clemson
110 Sloan St Clemson SC
Fully refundableReserve now, pay when you stay
The price is 4.001.751 ₫ per night from 16 Jun to 17 Jun
4.001.751 ₫
4.441.917 ₫ total
16 Jun - 17 Jun
includes taxes & fees
9.8/10 Exceptional! (816 reviews)
"Staff was very friendly and helpful."
Reviewed on 11 Jun 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.