Downtown Holidays
Book a Hotel + Flight or Car together to unlock savings
Where to stay in Downtown
Find the best Downtown areas and neighborhoods for the activities you enjoy most. Learn more about Downtown
Serenity Bay
When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.
Top hotels in Downtown
Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
Fully refundableReserve now, pay when you stay
The price is 2.029.158 ₫ per night from 7 Mar to 8 Mar
2.029.158 ₫
2.390.668 ₫ total
7 Mar - 8 Mar
includes taxes & fees
8/10 Very Good! (681 reviews)
All great
Reviewed on 21 Feb 2026
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
The price is 2.376.490 ₫ per night from 1 Mar to 2 Mar
2.376.490 ₫
2.637.905 ₫ total
1 Mar - 2 Mar
includes taxes & fees
8.2/10 Very Good! (1,005 reviews)
Clean room, courtesy of staff, safety
Reviewed on 28 Feb 2026
Wooded Cottage - 3 Mi to Clemson University
Clemson SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.