Find hotels in East Prairie, MO from 1.651.640 ₫

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Our top choices for East Prairie hotels

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,004 reviews)
"Very nice for overnight stay"
United States
Scott
The price is 2.471.937 ₫
2.842.109 ₫ total
includes taxes & fees
29 Mar - 30 Mar
Drury Inn & Suites Sikeston, MO

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (513 reviews)
"Great stay"
United States
grant
The price is 2.545.840 ₫
2.882.527 ₫ total
includes taxes & fees
12 Apr - 13 Apr
Hampton Inn Sikeston

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.2 out of 10, Very good, (53 reviews)
"Room was clean and fairly priced. "
United States
Mickey
The price is 1.704.240 ₫
1.946.463 ₫ total
includes taxes & fees
3 Apr - 4 Apr
Super 8 By Wyndham Marston

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (63 reviews)
"Nice quiet hotel "
United States
Steven
The price is 2.656.300 ₫
3.007.595 ₫ total
includes taxes & fees
29 Mar - 30 Mar
Fairfield Inn & Suites by Marriott Sikeston

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,000 reviews)
"nice and covenant have stay here a few times, staff always has a smile. "
United States
Roger
The price is 2.436.432 ₫
2.776.922 ₫ total
includes taxes & fees
29 Mar - 30 Mar
Best Western Plus Sikeston I-55

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (409 reviews)
"The staff was very friendly and accommodating "
United States
Arturo
The price is 1.841.000 ₫
2.043.050 ₫ total
includes taxes & fees
24 Mar - 25 Mar
The Riverstone Hotel Charleston-Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (449 reviews)
"Stay was excellent "
United States
Kourtney
The price is 2.445.900 ₫
2.769.370 ₫ total
includes taxes & fees
29 Mar - 30 Mar
Holiday Inn Express & Suites Sikeston Southwest by IHG

Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City
2.5 star property
Union City
8.6 out of 10, Excellent, (556 reviews)
"Very clean nice staff and well run "
United States
zach
The price is 1.893.337 ₫
2.248.387 ₫ total
includes taxes & fees
24 Mar - 25 Mar
Country Hearth Inn & Suites Union City

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (626 reviews)
"Affordable for a quick one night stay. Restaurant and gas station next to hotel."
United States
Annette
The price is 1.633.230 ₫
1.812.477 ₫ total
includes taxes & fees
24 Mar - 25 Mar
Super 8 by Wyndham Charleston/Sikeston East MO

Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
2.5 star property
Union City
9.2 out of 10, Wonderful, (368 reviews)
"Great stay. "
United States
Paul
The price is 1.988.280 ₫
2.361.082 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Sleep Inn at Discovery Park of America

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (753 reviews)
"The room was clean and comfortable. Check in staff was friendly. "
United States
Jennifer
The price is 1.722.387 ₫
1.963.091 ₫ total
includes taxes & fees
24 Mar - 25 Mar
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (474 reviews)
"Everything great "
United States
Jayla
The price is 1.833.636 ₫
2.104.097 ₫ total
includes taxes & fees
24 Mar - 25 Mar
Reelfoot Lake Inn

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very good, (753 reviews)
"The staff was great very helpful and friendly "
United States
Javier
New Orleans Inn Portageville

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.4 out of 10, Good, (1,001 reviews)
"Business friendly, clean room staff very friendly, accommodating."
United States
Janice
The price is 1.788.400 ₫
2.038.330 ₫ total
includes taxes & fees
25 Mar - 26 Mar
Days Inn and Suites by Wyndham Sikeston

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (282 reviews)
"Amenities, microwave, refrigerator,iron and iron board,Shower soap options "
United States
Maurice
The price is 1.886.499 ₫
2.093.637 ₫ total
includes taxes & fees
29 Mar - 30 Mar
Quality Inn Cairo I-57

Hampton Inn Union City

Hampton Inn Union City
2.5 star property
Union City
9.6 out of 10, Exceptional, (174 reviews)
"Spotless , friendly staff."
United States
Gail
The price is 2.674.184 ₫
3.175.594 ₫ total
includes taxes & fees
29 Mar - 30 Mar
Hampton Inn Union City

Quality Inn Union City US 51

Quality Inn Union City US 51
2.5 star property
Union City
8.4 out of 10, Very good, (500 reviews)
"All was pretty good except for the breakfast."
United States
Jeffrey
The price is 1.766.045 ₫
2.097.179 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Quality Inn Union City US 51

Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG
2.5 star property
Union City
9.4 out of 10, Exceptional, (316 reviews)
"The room was spacious & clean. The complimentary breakfast was nice. Very quiet place and next to a unique tourist attraction."
United States
Angela
The price is 2.840.400 ₫
3.372.975 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Holiday Inn Express & Suites Union City by IHG

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
6.8 out of 10, (603 reviews)
"Great place"
United States
Misty
The price is 1.585.890 ₫
1.807.336 ₫ total
includes taxes & fees
29 Mar - 30 Mar
Super 8 by Wyndham Sikeston/Miner Area

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (14 reviews)
"This hotel was great. Good location. Awesome staff. Hopefully I get the opportunity to stay here again."
United States
Jason
The price is 3.103.400 ₫
3.513.825 ₫ total
includes taxes & fees
2 Apr - 3 Apr
TownePlace Suites by Marriott Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

The Mississippi River near Hannibal, Missouri, USA

Top East Prairie Hotel Reviews

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Hotels in East Prairie with star rating

Frequently asked questions

What's the weather like in East Prairie?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for East Prairie is 1522 mm.