Find hotels in East Prairie, MO from 1.610.624 ₫

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Our top choices for East Prairie hotels

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,010 reviews)
"Nice place to stay"
United States
Lance
The price is 2.919.925 ₫
3.357.184 ₫ total
includes taxes & fees
15 May - 16 May
Drury Inn & Suites Sikeston, MO

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (556 reviews)
"Perfect nights stay!! "
United States
Amanda
The price is 2.772.863 ₫
3.139.573 ₫ total
includes taxes & fees
24 May - 25 May
Hampton Inn Sikeston

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very good, (763 reviews)
"The staff was great very helpful and friendly "
United States
Javier
The price is 1.491.664 ₫
1.610.624 ₫ total
includes taxes & fees
10 May - 11 May
New Orleans Inn Portageville

Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City
2.5 star property
Union City
8.6 out of 10, Excellent, (570 reviews)
"Very clean nice staff and well run "
United States
zach
The price is 1.574.271 ₫
1.869.447 ₫ total
includes taxes & fees
8 Jun - 9 Jun
Country Hearth Inn & Suites Union City

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (412 reviews)
"All very just okay "
United States
Sherry
The price is 1.973.100 ₫
2.189.648 ₫ total
includes taxes & fees
9 May - 10 May
The Riverstone Hotel Charleston-Sikeston

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (772 reviews)
"Breakfast was adequate room was clean."
United States
Daniel
The price is 1.538.755 ₫
1.753.796 ₫ total
includes taxes & fees
10 May - 11 May
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (631 reviews)
"Affordable for a quick one night stay. Restaurant and gas station next to hotel."
United States
Annette
The price is 1.610.050 ₫
1.786.840 ₫ total
includes taxes & fees
1 Jun - 2 Jun
Super 8 by Wyndham Charleston/Sikeston East MO

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,002 reviews)
"Very nice folks who manage the hotel!!"
United States
Jane
The price is 2.380.085 ₫
2.712.700 ₫ total
includes taxes & fees
1 Jun - 2 Jun
Best Western Plus Sikeston I-55

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (462 reviews)
"Clean rooms, friendly staff and convenient location."
United States
Mark
The price is 2.657.108 ₫
3.008.510 ₫ total
includes taxes & fees
7 Jun - 8 Jun
Holiday Inn Express & Suites Sikeston Southwest by IHG

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (74 reviews)
"The breakfast was good, the service was good, and the staff was very friendly"
United States
Angela
The price is 2.893.880 ₫
3.276.595 ₫ total
includes taxes & fees
21 May - 22 May
Fairfield Inn & Suites by Marriott Sikeston

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very good, (62 reviews)
"Great hotel for the price!!! Remodel very nice and modern. "
United States
Amy
The price is 1.787.272 ₫
2.041.511 ₫ total
includes taxes & fees
30 May - 31 May
Super 8 By Wyndham Marston

Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
2.5 star property
Union City
9.2 out of 10, Wonderful, (385 reviews)
"Great stay. "
United States
Paul
The price is 2.224.341 ₫
2.641.586 ₫ total
includes taxes & fees
24 May - 25 May
Sleep Inn at Discovery Park of America

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1,002 reviews)
"Business friendly, clean room staff very friendly, accommodating."
United States
Janice
The price is 1.704.758 ₫
1.942.998 ₫ total
includes taxes & fees
10 May - 11 May
Days Inn and Suites by Wyndham Sikeston

Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51
2.5 star property
Union City
6.8 out of 10, (391 reviews)
"Easy to check in.. Clean Room..Lots of food options near by.. "
United States
Pooran
The price is 1.499.556 ₫
1.780.789 ₫ total
includes taxes & fees
13 May - 14 May
Hospitality House Union City I 69 / US 51

Quality Inn Union City US 51

Quality Inn Union City US 51
2.5 star property
Union City
8.4 out of 10, Very good, (509 reviews)
"Bathroom walls were dirty and bathroom ceiling had mold on it"
United States
Emily
The price is 1.824.460 ₫
2.166.464 ₫ total
includes taxes & fees
17 May - 18 May
Quality Inn Union City US 51

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (106 reviews)
"Great"
United States
Jackson
The price is 1.822.881 ₫
2.023.085 ₫ total
includes taxes & fees
9 May - 10 May
Eagle Inn Charleston

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
6.8 out of 10, (622 reviews)
"Cheap room not bad for the price. Would stay again if I was in the area. "
United States
Jenny
The price is 1.654.773 ₫
1.886.027 ₫ total
includes taxes & fees
15 May - 16 May
Super 8 by Wyndham Sikeston/Miner Area

Hampton Inn Union City

Hampton Inn Union City
2.5 star property
Union City
9.6 out of 10, Exceptional, (182 reviews)
"Spotless , friendly staff."
United States
Gail
The price is 2.907.034 ₫
3.452.399 ₫ total
includes taxes & fees
24 May - 25 May
Hampton Inn Union City

Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG
2.5 star property
Union City
9.4 out of 10, Exceptional, (325 reviews)
"Great hotel. Well worth it"
United States
Shannon
The price is 3.025.420 ₫
3.592.685 ₫ total
includes taxes & fees
17 May - 18 May
Holiday Inn Express & Suites Union City by IHG

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (285 reviews)
"Amenities, microwave, refrigerator,iron and iron board,Shower soap options "
United States
Maurice
The price is 1.872.867 ₫
2.078.509 ₫ total
includes taxes & fees
5 Jun - 6 Jun
Quality Inn Cairo I-57
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

The Mississippi River near Hannibal, Missouri, USA

Top East Prairie Hotel Reviews

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Hotels in East Prairie with star rating

Frequently asked questions

What's the weather like in East Prairie?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for East Prairie is 1522 mm.