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Check availability on Florence Hotels Suites

Our top choices for Florence hotels with suites

Lobby
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2493)
"I nice place to stay, very quiet, good breakfast, nice staff, spotless room. "
United States
Timothy
The price is 1.633.665 ₫
1.829.706 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Howard Johnson by Wyndham Florence
Lobby
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.2 out of 10, Wonderful, (1165)
"Enjoyed our stay there. "
United States
Cathy
The price is 2.603.867 ₫
2.916.330 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Comfort Inn & Suites Florence Center Area
Exterior
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2194)
"Breakfast was great, room very clean ."
United States
Leann
The price is 2.367.630 ₫
2.651.744 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Park Inn by Radisson Florence, SC
Front of property – evening/night
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
8.8 out of 10, Excellent, (1006)
"Great stay"
United States
Michaelle
The price is 2.630.700 ₫
2.946.384 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hyatt Place Florence Downtown
Reception
Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
Florence
9.0 out of 10, Wonderful, (816)
"Very friendly and responsive staff. Very clean and comfortable room. Would definitely stay there again when we pass this way. "
United States
Maggie
The price is 2.504.426 ₫
2.804.957 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn & Suites Florence Center
Terrace/patio
Tru by Hilton Florence I-95

Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.4 out of 10, Very good, (1005)
"Hotel was clean , friendly staff"
United States
Gabriela
The price is 2.399.198 ₫
2.779.440 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Tru by Hilton Florence I-95
Exterior
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1004)
"Room was clean, staff was courteous and breakfast was great !"
United States
Angela
The price is 3.209.454 ₫
3.594.588 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Free daily continental breakfast
Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville
2.5 star property
Hartsville
8.6 out of 10, Excellent, (677)
"Good for overnight stay. Breakfast was a little disappointing….not much variety and hot food was warm at best. Room was very nice. Not familiar with area but hotel is in middle of downtown. "
United States
Lon
The price is 2.213.734 ₫
2.479.380 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Fairfield Inn by Marriott Hartsville
Lobby sitting area
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.0 out of 10, Very good, (25)
"Friendly staff and clean environment "
United States
john
The price is 2.399.198 ₫
2.791.015 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Spark by Hilton Florence North I-95, SC
Free daily buffet breakfast
Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville
2.5 star property
Hartsville
9.2 out of 10, Wonderful, (479)
"Staff was very friendly and accommodating!! Rooms were very clean! "
United States
Julia
The price is 3.135.794 ₫
3.512.090 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hampton Inn & Suites Hartsville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Florence Hotel Reviews

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Frequently asked questions

What are the best hotels with suites in Florence?
Florence offers multiple hotels with suites that have a total average guest review rating of 8.6. Staybridge Suites Florence - Civic Centre, an IHG Hotel is a fantastic option if you're looking for extra space to kick back and relax. Reserve a room at this top-rated 3-star stay and get access to a swimming pool and designer toiletries. Hampton Inn & Suites Florence Centre is another popular choice. This 2.5-star retreat has suites and features amenities such as a swimming pool and golf.
What are the best cheap hotels with suites in Florence?
Hotels with suites are priced from 1.829.706 ₫ per night, so you may want to stay longer in Florence! One escape that's easy on your budget is Hampton Inn & Suites Florence Centre. It includes a swimming pool and laundry services. Comfort Inn & Suites also offers low-cost suite rooms and amenities like pillow top mattresses and front desk services. If you're exploring Florence and want to save money, there are many fabulous free attractions to put on your itinerary. Florence Museum and Mcleod Regional Medical Centre are worth stopping by. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels with suites in Florence?
Treat the crew to a stay at Hampton Inn & Suites Florence Centre, a 2.5-star option just a short drive from downtown. You'll have access to complimentary breakfast and WiFi along with spacious rooms. Another family-friendly hotel with suites in Florence is La Quinta Inn & Suites by Wyndham Florence. Complimentary breakfast and WiFi help make this 2.5-star property a hit with guests. Once you've checked in and unpacked your bags, there are tons of family-friendly attractions to discover around Florence. Columns Plantation and Florence Museum guarantee a good time for young and old.
Why book your hotel with suites in Florence with Expedia?
Expedia has the best deals on hotels with suites in Florence. But our fantastic prices are just the start. You'll discover a wide range of stays to choose from and search filters that make it a breeze to find your perfect match. So why delay? Your Florence escape is only a few clicks away!
How can I find cheap hotels with suites in Florence?
Finding a cheap stay with suites in Florence is a cinch with Expedia. Just use the filter tool to select the hotel star rating you prefer, then decide on your nightly budget. Choosing fewer amenities can also lead to more savings.
What is there to do in Florence near my hotel with suites?
You'll find loads of fantastic things to fill your itinerary with in Florence. Make tracks to major attractions like Florence Museum, Florence Civic Centre and Palmetto Shores Lake. Oakdale Country Club, The Traces Golf Club and Florence Veterans Park also lure many visitors.