Search Spa Hotels in Florida Keys

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Florida Keys Spa Hotels

Next weekend
In two weeks

Top Florida Keys Spa Hotels

Our top choices for Florida Keys hotels with a spa

Isla Bella Beach Resort & Spa

5.0 star property
9.2 out of 10, Wonderful, (1033)
"Beautiful hotel with fantastic facilities and stunning views. Great spot for some family downtime - the kids loved the pools and the linked fishing charters were awesome "
The price is 6.150.208 ₫
8.490.712 ₫ total
includes taxes & fees
21 Sept - 22 Sept
Isla Bella Beach Resort & Spa

Coconut Palm Inn

3.0 star property
9.4 out of 10, Exceptional, (526)
"Great place to stay ! Very pleasant staff. "
The price is 6.352.278 ₫
7.937.185 ₫ total
includes taxes & fees
25 Aug - 26 Aug
Coconut Palm Inn

Reefhouse Resort & Marina

3.5 star property
9.2 out of 10, Wonderful, (1301)
"Great stay"
The price is 5.772.402 ₫
7.548.404 ₫ total
includes taxes & fees
26 Aug - 27 Aug
Reefhouse Resort & Marina

Playa Largo Resort & Spa, Autograph Collection

4.5 star property
9.0 out of 10, Wonderful, (1003)
"Love this property and the food is amazing!"
The price is 6.299.562 ₫
8.540.124 ₫ total
includes taxes & fees
7 Sept - 8 Sept
Playa Largo Resort & Spa, Autograph Collection

Pines & Palms Resort

3.0 star property
9.2 out of 10, Wonderful, (1000)
"Clean, nice beach and pool area we had a great time. Highly recommend it."
Pines & Palms Resort

Kona Kai Resort and Gallery - Adults Only

2.5 star property
9.8 out of 10, Exceptional, (252)
"I truly enjoyed this resort. Extremely friendly staff, beautiful room and the view on the water is grwat"
Kona Kai Resort and Gallery - Adults Only

Oceans Edge Key West Resort, Hotel & Marina

4.0 star property
9.0 out of 10, Wonderful, (1723)
"Amazing place to stay! "
The price is 4.420.381 ₫
6.505.382 ₫ total
includes taxes & fees
7 Sept - 8 Sept
Oceans Edge Key West Resort, Hotel & Marina

Pier House Resort & Spa

4.0 star property
9.0 out of 10, Wonderful, (1005)
"Nice property with good beach bar and friendly staff!"
Pier House Resort & Spa

Parrot Key Hotel & Villas

4.0 star property
9.0 out of 10, Wonderful, (1058)
"Great view. Great staff and very clean"
The price is 3.400.182 ₫
5.337.627 ₫ total
includes taxes & fees
1 Sept - 2 Sept
Parrot Key Hotel & Villas

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

3.5 star property
9.0 out of 10, Wonderful, (63)
"Great resort, excellent staff and customer service, I'll definitely coming back "
The price is 4.906.542 ₫
7.269.503 ₫ total
includes taxes & fees
26 Aug - 27 Aug
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Florida Keys Hotel Reviews