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Check prices for these dates

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13 Jan - 14 Jan
Tomorrow
14 Jan - 15 Jan
This weekend
16 Jan - 18 Jan
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23 Jan - 25 Jan

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Our top choices for Florida Keys National Marine Sanctuary hotels

Exterior detail
The Gardens Hotel

The Gardens Hotel

The Gardens Hotel
4.0 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,001 reviews)
"Good place"
United States
Salvador
The price is 12.382.550 ₫
13.930.370 ₫ total
includes taxes & fees
14 Jan - 15 Jan
The Gardens Hotel
Property grounds
Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
3.5 star property
Uptown - Upper Duval, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,002 reviews)
"Convenient location, staff was friendly and helpful"
United States
Melissa
The price is 8.991.879 ₫
10.115.863 ₫ total
includes taxes & fees
14 Jan - 15 Jan
Orchid Key Inn - Adults Only
Exterior
The Marquesa Hotel

The Marquesa Hotel

The Marquesa Hotel
3.5 star property
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,001 reviews)
"Perfect place to stay. "
United States
Paulette
The price is 9.668.515 ₫
12.354.739 ₫ total
includes taxes & fees
15 Jan - 16 Jan
The Marquesa Hotel
Queen with Pool View | Minibar, in-room safe, individually decorated, individually furnished
Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages
2.5 star property
Historic Seaport, 1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (897 reviews)
"Great location and staff. The room was clean and comfortable, nice and quiet."
United States
Jesus
The price is 13.108.231 ₫
14.746.759 ₫ total
includes taxes & fees
14 Jan - 15 Jan
Simonton Court Historic Inn & Cottages
11 Gecko's Garden - Adults Only | Premium bedding, pillow-top beds, individually decorated
Tropical Inn

Tropical Inn

Tropical Inn
3.5 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (368 reviews)
"Nice place to stay "
United States
yulio
The price is 6.168.487 ₫
7.596.207 ₫ total
includes taxes & fees
14 Jan - 15 Jan
Tropical Inn
Deluxe Suite, 1 King Bed, Private Pool | View from room
H2O Suites - Adults Only

H2O Suites - Adults Only

H2O Suites - Adults Only
3.5 star property
Uptown - Upper Duval, 1.1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (582 reviews)
"Great place!!"
United States
Joel
The price is 16.260.511 ₫
20.066.232 ₫ total
includes taxes & fees
19 Jan - 20 Jan
H2O Suites - Adults Only
Exterior
Douglas House

Douglas House

Douglas House
3.0 star property
Uptown - Upper Duval, 0.9 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (251 reviews)
"Loved the hotel will definitely stay again "
United States
Christina
The price is 9.328.558 ₫
11.544.091 ₫ total
includes taxes & fees
28 Jan - 29 Jan
Douglas House
Property grounds
Duval House

Duval House

Duval House
3.0 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,019 reviews)
"Great place! "
United States
David
The price is 7.854.431 ₫
9.401.020 ₫ total
includes taxes & fees
20 Jan - 21 Jan
Duval House
Cigar House King Suite w/ Poolside porch | Balcony view
Island City House Hotel

Island City House Hotel

Island City House Hotel
3.0 star property
Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,001 reviews)
"Excellent stay"
United States
Emily Barbara
The price is 9.607.887 ₫
10.808.872 ₫ total
includes taxes & fees
14 Jan - 15 Jan
Island City House Hotel
Courtyard
The Grand Guesthouse

The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West, 1.6 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,003 reviews)
"Great stay"
United States
Ginger
The Grand Guesthouse
2 outdoor pools, pool loungers
Santa Maria Suites

Santa Maria Suites

Santa Maria Suites
4.0 star property
Uptown - Upper Duval, 1.3 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,007 reviews)
"Awesome place we loved it"
United States
Josh
The price is 13.369.394 ₫
16.813.523 ₫ total
includes taxes & fees
15 Jan - 16 Jan
Santa Maria Suites
Terrace/patio
Marrero's Guest Mansion

Marrero's Guest Mansion

Marrero's Guest Mansion
3.5 star property
Downtown Key West, 0.7 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (335 reviews)
"Location very good Staff friendly Pool not well maintained Breakfast and happy hour lacking compared to others"
United States
Scott
The price is 11.164.325 ₫
12.559.997 ₫ total
includes taxes & fees
14 Jan - 15 Jan
Marrero's Guest Mansion
Outdoor pool, open 8:00 AM to 10:00 PM, pool loungers
Ella's Cottages - Key West Historic Inns

Ella's Cottages - Key West Historic Inns

Ella's Cottages - Key West Historic Inns
3.5 star property
Old Town Key West, 0.9 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (422 reviews)
"Excellent food, location, friendly staff and pool was awesome."
United States
Karen
The price is 10.472.137 ₫
13.111.153 ₫ total
includes taxes & fees
14 Jan - 15 Jan
Ella's Cottages - Key West Historic Inns
Front of property – evening/night
Southernmost House

Southernmost House

Southernmost House
4.0 star property
Uptown - Upper Duval, 1.2 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,001 reviews)
"Great place to stay. Staff was very friendly"
United States
Jacob
The price is 12.270.250 ₫
16.242.124 ₫ total
includes taxes & fees
15 Jan - 16 Jan
Southernmost House
Lobby sitting area
Westwinds Inn

Westwinds Inn

Westwinds Inn
3.5 star property
Historic Seaport, 1.4 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,007 reviews)
"Enjoyed our stay."
United States
Cindy
Westwinds Inn
Front of property – evening/night
Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
4.0 star property
Old Town Key West, 0.9 km from Florida Keys National Marine Sanctuary
9.2 out of 10, Wonderful, (1,023 reviews)
"The staff was so friendly and the amenities were perfect. Great location to watch the sunset at. "
United States
Jamie
The price is 12.320.161 ₫
14.894.785 ₫ total
includes taxes & fees
28 Jan - 29 Jan
Opal Key Resort & Marina, Key West
Property grounds
Paradise Inn Key West - Adults Only

Paradise Inn Key West - Adults Only

Paradise Inn Key West - Adults Only
3.5 star property
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
9.2 out of 10, Wonderful, (1,004 reviews)
"Perfect location and nice room,breakfast is ok"
Canada
Guang
Paradise Inn Key West - Adults Only
Outdoor pool, pool loungers
Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
4.0 star property
Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary
9.2 out of 10, Wonderful, (1,008 reviews)
"Upon arrival everything about this resort, the staff the room the views made our trip to Key West that much better thank you"
United States
Randy
The price is 13.896.301 ₫
17.672.600 ₫ total
includes taxes & fees
14 Jan - 15 Jan
Ocean Key Resort - A Noble House Resort
Outdoor pool
The Key West Hotel

The Key West Hotel

The Key West Hotel
2.5 star property
Historic Seaport, 0.9 km from Florida Keys National Marine Sanctuary
9.2 out of 10, Wonderful, (517 reviews)
"location was great nice bar party vibe"
United States
Robert Howard
The price is 9.161.952 ₫
11.751.991 ₫ total
includes taxes & fees
14 Jan - 15 Jan
The Key West Hotel
Front of property
Winslow's Bungalows - Key West Historic Inns

Winslow's Bungalows - Key West Historic Inns

Winslow's Bungalows - Key West Historic Inns
4.0 star property
Old Town Key West, 1.2 km from Florida Keys National Marine Sanctuary
9.2 out of 10, Wonderful, (1,119 reviews)
"Great place , amazing breakfast, staff was very nice "
United States
Robert
The price is 9.154.746 ₫
11.629.089 ₫ total
includes taxes & fees
14 Jan - 15 Jan
Winslow's Bungalows - Key West Historic Inns
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Florida Keys National Marine Sanctuary Hotel Reviews

Hyatt Vacation Club at Sunset Harbor, Key West

Hyatt Vacation Club at Sunset Harbor, Key West

10/10 Excellent
"Great place to stay! "
Alicia 1-night trip
Posted 6 days ago
Hyatt Vacation Club at Sunset Harbor, Key West

Hotels near other Florida Keys National Marine Sanctuary attractions

Florida Keys Eco - Discovery Center which includes interior views

Florida Keys Eco - Discovery Center

4.3/5 (128 reviews)
You can spend an afternoon browsing the exhibits at Florida Keys Eco - Discovery Center in Key West. Discover the area's lively bars and its lively festivals.
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Fort Zachary Taylor Park, Key West. State Park in Florida, USA., Shutterstock ID 761867707, Purchase Order: SP-1891 Wave 0, Client/Licensee: Hotels.com

Fort Zachary Taylor Historic State Park

4.4/5 (1,160 reviews)
Enjoy a trip to Fort Zachary Taylor Historic State Park and popular activities such as boating in Key West. Discover the area's beautiful sunsets or seek out its cycling trails.
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Frequently asked questions

What's the area like around Florida Keys National Marine Sanctuary?
Florida Keys National Marine Sanctuary is located in an area of Key West known for its beautiful ocean views, cycling and lively festivals. If you're looking for a convenient place to stay, take a look at the 1604 hotels and other accommodation options you'll find within a mile.
How many hotels will I find near Florida Keys National Marine Sanctuary?
Expedia has 1604 hotels and other accommodation options within a mile from Florida Keys National Marine Sanctuary.
If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best deals near Florida Keys National Marine Sanctuary.
What can I see and do near Florida Keys National Marine Sanctuary?
Florida Keys Eco - Discovery Center, Harry S. Truman Little White House and Key West Lighthouse and Keeper's Quarters Museum feature captivating exhibits. Fort Zachary Taylor Historic State Park, Ernest Hemingway Home and Museum and Audubon House and Tropical Gardens are some of the notable landmarks to see in the area. You can watch performances at Red Barn Theater, Waterfront Playhouse and Key West Film Society if you're interested in local theatre.