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Check prices for these dates

This weekend
5 Jun - 7 Jun
Next weekend
12 Jun - 14 Jun

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Our top choices for Florida Keys National Marine Sanctuary hotels

Queen Deluxe ADA | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds

Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
3.5 star property
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
10.0 out of 10, Exceptional, (1,001 reviews)
"Excellent accommodations"
United States
Jimmy
The price is 6.704.552 ₫
7.542.621 ₫ total
includes taxes & fees
2 Jun - 3 Jun
Almond Tree Inn Hotel - Adults Only
Exterior detail

The Gardens Hotel

The Gardens Hotel
4.0 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,002 reviews)
"Best hotel ive ever stayed in, the hospitality was unmatched."
United States
Markus
The price is 7.074.908 ₫
7.959.272 ₫ total
includes taxes & fees
28 Jun - 29 Jun
The Gardens Hotel
Front of property

Key West Villas

Key West Villas
3.5 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (261 reviews)
"This was the best place we have stayed at in Key West! It was super quiet but only a block from Duval. The owners really put a lot of care into the place and are super nice! Definitely would stay there again! "
United States
Jennifer
Key West Villas
Property grounds

Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
3.5 star property
Uptown - Upper Duval, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,003 reviews)
"Great boutique hotel in the perfect location !! "
United States
Michael
The price is 5.798.070 ₫
6.522.829 ₫ total
includes taxes & fees
8 Jun - 9 Jun
Orchid Key Inn - Adults Only
11 Gecko's Garden - Adults Only | Premium bedding, pillow-top beds, individually decorated

Tropical Inn

Tropical Inn
3.5 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (406 reviews)
"Very friendly staff and a prime location."
United States
Akhenaton
The price is 4.443.213 ₫
5.656.242 ₫ total
includes taxes & fees
8 Jun - 9 Jun
Tropical Inn
Exterior

Douglas House - Adults Only

Douglas House - Adults Only
3.0 star property
Uptown - Upper Duval, 0.9 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (402 reviews)
"Great stay"
United States
Matthew
The price is 3.894.023 ₫
4.818.853 ₫ total
includes taxes & fees
4 Jun - 5 Jun
Douglas House - Adults Only
Queen with Pool View | Minibar, in-room safe, individually decorated, individually furnished

Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages
2.5 star property
Historic Seaport, 1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (969 reviews)
"Great stay overall! Friendly staff, clean rooms, and a perfect location for exploring the Keys and relaxing in this little paradise 🌴"
United States
Olha
The price is 4.710.027 ₫
5.298.780 ₫ total
includes taxes & fees
3 Jun - 4 Jun
Simonton Court Historic Inn & Cottages
Exterior

The Marquesa Hotel

The Marquesa Hotel
3.5 star property
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,000 reviews)
"Great accommodations and great staff"
United States
Julian
The price is 8.130.717 ₫
10.627.294 ₫ total
includes taxes & fees
2 Jun - 3 Jun
The Marquesa Hotel
Premium bedding, iron/ironing board, free WiFi, bed sheets

Weatherstation Inn

Weatherstation Inn
2.5 star property
Truman Annex, 0.6 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,003 reviews)
"Perfect stay!"
United States
A. Elise
The price is 4.710.027 ₫
5.298.780 ₫ total
includes taxes & fees
2 Jun - 3 Jun
Weatherstation Inn
Veranda Room | Terrace/patio

The Conch House Heritage Inn

The Conch House Heritage Inn
3.5 star property
Old Town Key West, 1.1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (175 reviews)
"Great location "
United Kingdom
Lucy
The price is 6.251.969 ₫
7.033.465 ₫ total
includes taxes & fees
9 Jun - 10 Jun
The Conch House Heritage Inn
Exterior

Coco Plum Inn

Coco Plum Inn
3.0 star property
Downtown Key West, 0.6 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (532 reviews)
"Loved the property and staff was super friendly."
United States
Brinkley
The price is 5.329.435 ₫
5.995.680 ₫ total
includes taxes & fees
2 Jun - 3 Jun
Coco Plum Inn
Deluxe Suite, 1 King Bed, Private Pool | View from room

H2O Suites - Adults Only

H2O Suites - Adults Only
3.5 star property
Uptown - Upper Duval, 1.1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (610 reviews)
"We had a wonderful stay!"
United States
Elizabeth
The price is 8.656.977 ₫
11.515.227 ₫ total
includes taxes & fees
2 Jun - 3 Jun
H2O Suites - Adults Only
Front of property

L'Habitation Guest House

L'Habitation Guest House
2.5 star property
Historic Seaport, 0.8 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (985 reviews)
"The location and customer service were excellent. We loved our stay!"
United States
Megan
The price is 3.291.756 ₫
3.703.554 ₫ total
includes taxes & fees
2 Jun - 3 Jun
L'Habitation Guest House
Cigar House King Suite w/ Poolside porch | Balcony view

Island City House Hotel

Island City House Hotel
3.0 star property
Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,000 reviews)
"Well maintained property, clean room and close to everything!!!"
United States
Troy
The price is 4.458.224 ₫
5.015.502 ₫ total
includes taxes & fees
2 Jun - 3 Jun
Island City House Hotel
Property grounds

Duval House

Duval House
3.0 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,035 reviews)
"Great location and staff"
United States
gerald
The price is 3.657.507 ₫
4.680.425 ₫ total
includes taxes & fees
3 Jun - 4 Jun
Duval House
3 outdoor pools, a heated pool, pool loungers

Ambrosia Key West

Ambrosia Key West
3.5 star property
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,001 reviews)
"Great location and breakfast"
United States
Lori
The price is 6.501.963 ₫
7.314.708 ₫ total
includes taxes & fees
3 Jun - 4 Jun
Ambrosia Key West
2 outdoor pools, pool loungers

Santa Maria Suites

Santa Maria Suites
4.0 star property
Uptown - Upper Duval, 1.3 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,000 reviews)
"A beautiful place to stay"
United States
Jill
The price is 8.130.717 ₫
10.923.184 ₫ total
includes taxes & fees
22 Jun - 23 Jun
Santa Maria Suites
Property grounds

Paradise Inn Key West - Adults Only

Paradise Inn Key West - Adults Only
3.5 star property
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
9.2 out of 10, Wonderful, (1,002 reviews)
"Our stay was great! The staff was friendly and the resort was always being maintained."
United States
Paul
The price is 5.520.204 ₫
7.394.052 ₫ total
includes taxes & fees
1 Jul - 2 Jul
Paradise Inn Key West - Adults Only
Front of property

Caribbean House

Caribbean House
3.0 star property
Bahama Village, 0.5 km from Florida Keys National Marine Sanctuary
9.0 out of 10, Wonderful, (366 reviews)
"Had a wonderful stay"
Canada
Jeff
The price is 3.355.697 ₫
4.432.984 ₫ total
includes taxes & fees
2 Jun - 3 Jun
Caribbean House
Porch

Heron House - Adult Only

Heron House - Adult Only
3.5 star property
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
9.2 out of 10, Wonderful, (1,151 reviews)
"Fantastic place, clean and great location."
United States
James
The price is 3.122.827 ₫
4.390.456 ₫ total
includes taxes & fees
2 Jun - 3 Jun
Heron House - Adult Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels close to Florida Keys National Marine Sanctuary

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Queen Deluxe ADA | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds
Almond Tree Inn Hotel - Adults Only
3.5 star property
10.0
Exceptional
1,001 reviews
View
Exterior detail
The Gardens Hotel
4.0 star property
9.8
Exceptional
1,002 reviews
View
Front of property
Key West Villas
3.5 star property
9.8
Exceptional
261 reviews
View
Property grounds
Orchid Key Inn - Adults Only
3.5 star property
9.8
Exceptional
1,003 reviews
View
11 Gecko's Garden - Adults Only | Premium bedding, pillow-top beds, individually decorated
Tropical Inn
3.5 star property
9.6
Exceptional
406 reviews
View

Top Florida Keys National Marine Sanctuary Hotel Reviews

Southwinds Motel

Southwinds Motel

10/10 Excellent
"The rooms are nice. They provide necessary amenities and are cleaned well. Not a lot of space, but fair for a motel setting. There is loud music next door at a bar, which I enjoyed, but that’s something to be aware of if you’re a light sleeper. The staff was helpful and this area of the island was very nice. Overall, it was a nice stay!"
Memphis 4-night trip
Posted 10 hours ago
Southwinds Motel

Hotels near other Florida Keys National Marine Sanctuary attractions

Florida Keys Eco - Discovery Center

4.4/5 (128 reviews)
You can spend an afternoon browsing the exhibits at Florida Keys Eco - Discovery Center in Key West. Discover the area's lively bars and its lively festivals.
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Frequently asked questions

What's the area like around Florida Keys National Marine Sanctuary?
Florida Keys National Marine Sanctuary is located in an area of Key West known for its beautiful ocean views, cycling and lively festivals. If you're looking for a convenient place to stay, take a look at the 1545 hotels and other accommodation options you'll find within a mile.
How many hotels will I find near Florida Keys National Marine Sanctuary?
Expedia has 1545 hotels and other accommodation options within a mile from Florida Keys National Marine Sanctuary.
If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best deals near Florida Keys National Marine Sanctuary.
What can I see and do near Florida Keys National Marine Sanctuary?
Florida Keys Eco - Discovery Center, Harry S. Truman Little White House and Key West Lighthouse and Keeper's Quarters Museum feature captivating exhibits. Fort Zachary Taylor Historic State Park, Ernest Hemingway Home and Museum and Audubon House and Tropical Gardens are some of the notable landmarks to see in the area. You can watch performances at Waterfront Playhouse, Key West Film Society and Red Barn Theater if you're interested in local theatre.