Fort Myers River District Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in Fort Myers River District

Find the best Fort Myers River District areas and neighborhoods for the activities you enjoy most. Learn more about Fort Myers River District
Aerial view of the road bridge between Captiva Island and Sanibel Island in Lee County, Florida, United States

Iona

While visiting Iona, you might make a stop by sights like Estero Bay Preserve State Park and Tribby Arts Center.

Find hotels in Iona

Top hotels in Fort Myers River District

Hampton Inn Fort Myers Downtown

Hampton Inn Fort Myers Downtown

3 out of 5
2151 Johnson Street Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is 3.869.806 ₫ per night from 5 Apr to 6 Apr
3.869.806 ₫
4.314.833 ₫ total
5 Apr - 6 Apr
includes taxes & fees
9.2/10 Wonderful! (918 reviews)
Good WiFi

Reviewed on 23 Mar 2026

Hampton Inn Fort Myers Downtown
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
The price is 9.461.567 ₫ per night from 19 Apr to 20 Apr
9.461.567 ₫
11.871.790 ₫ total
19 Apr - 20 Apr
includes taxes & fees
9/10 Wonderful! (1,960 reviews)
I love the Marguaritaville resorts, Hollywood Beach, Gatlinburg, key West and now Fort Myers. I had to call this time to get a receipt of charges and the desk person acted surprised that I asked. The charges that they emailed me were like $350.00 less than what my pending charge was on credit card ...

Reviewed on 24 Mar 2026

Margaritaville Beach Resort Fort Myers
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
Fully refundableReserve now, pay when you stay
The price is 9.714.663 ₫ per night from 12 Apr to 13 Apr
9.714.663 ₫
11.490.025 ₫ total
12 Apr - 13 Apr
includes taxes & fees
9.2/10 Wonderful! (1,723 reviews)
We loved having the option to sit by the pool or by the beach! We appreciated that the staff set out the chairs daily. The cafe had delicious ice lattes and we enjoyed lunch by the pool. Checkout was easy!

Reviewed on 24 Mar 2026

Sanibel Island Beach Resort
See all 13,722 properties in Fort Myers River District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Fort Myers River District holiday package cost?
Perhaps less than you imagined — from a low , actually! By combining hotels, flights and car rentals into a tailor-made holiday package, your trip to Fort Myers River District is just clicks away.
How do I get a cheap travel package to Fort Myers River District?
Combine your flight and hotel bookings, add extras such as activities or a rental car, and save with a Fort Myers River District holiday package. You won't just walk away with exciting discounts on your adventure — you'll have a world of choice too. When you book through Expedia, you'll have your pick of over 550 partner airlines and 1null000null000 properties around the world. Your affordable holiday starts right here, right now!
How far in advance should I book my Fort Myers River District holiday?
Be rewarded with the widest variety and the lowest prices by booking your trip to Fort Myers River District early. Airlines usually sell flights around 12 months in advance, so start your planning as soon as possible. Having said that, Expedia is constantly working to give you the best bargains around, so there's never a bad time to book your dream holiday!
What does an Expedia Fort Myers River District travel package include?
Car rentals, flights and hotels — we connect you to the very best deals. All you'll have to do is figure out your preferred combination. After you've made your booking, you can add on the fun stuff like activities and sightseeing tours. Our travel packages make it simple to create an amazing Fort Myers River District holiday.
What should I know before booking a Fort Myers River District travel package?
Our prices are always low. However, you'll enjoy an even better deal when you book your flights, hotels and car rentals together. With an Expedia package, you'll always get transparent pricing and loads of choice.
Can I choose my airline with a Fort Myers River District Expedia holiday package?
Expedia has access to more than 550 airline partners worldwide, so you certainly can. Just choose the carrier that suits you and put together your ideal Fort Myers River District getaway.
If I'm not able to travel, can I cancel my Fort Myers River District holiday package?
If your holiday plans in Fort Myers River District have changed, it's comforting to know that it's possible to cancel your booking. If your booking was made within the last 24 hours, you may be able to get a refund. If your booking is older than that, your hotel, airline or car rental company may charge a fee. For more information, check our Customer Service Portal.

Popular places to visit

Florida Repertory Theater showing signage

Florida Repertory Theater

You can enjoy a show at Florida Repertory Theater on your trip to Fort Myers. You can attend a baseball game while in the area.

Florida Repertory Theater
Edison Mall featuring signage

Edison Mall

You can enjoy retail therapy at Edison Mall during your trip to Fort Myers. Attend a baseball game or discover the beautiful sunsets in this family-friendly area.

Edison Mall
Edison and Ford Winter Estates featuring street scenes and a house

Edison and Ford Winter Estates

You can spend time browsing the exhibits at Edison and Ford Winter Estates during your travels in Fort Myers. Stroll along the marina or attend a baseball game in the area.

Edison and Ford Winter Estates