Search Hotels Near Key West National Wildlife Refuge, Key West

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Our top choices for Key West National Wildlife Refuge hotels

King Room D | Balcony
Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages
2.5 star property
Historic Seaport, 11.4 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (883)
"The staff was really nice"
United States
doug
The price is 10.762.835 ₫
12.108.189 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Simonton Court Historic Inn & Cottages
Queen Deluxe ADA | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds
Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
3.5 star property
Downtown Key West, 11.8 km from Key West National Wildlife Refuge
10.0 out of 10, Exceptional, (1002)
"Great location, spotless rooms, attentive and friendly staff, great value."
United States
David
The price is 10.340.969 ₫
11.633.591 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Almond Tree Inn Hotel - Adults Only
Front of property
L'Habitation Guest House

L'Habitation Guest House

L'Habitation Guest House
2.5 star property
Historic Seaport, 11.2 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (924)
"A great no hassle stay."
United States
Gary
The price is 6.679.273 ₫
7.514.248 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
L'Habitation Guest House
Premium bedding, iron/ironing board, free WiFi, bed sheets
Weatherstation Inn

Weatherstation Inn

Weatherstation Inn
2.5 star property
Truman Annex, 11 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (996)
"Wonderful property safe neighborhood convenient to all activities would stay here again."
United States
William
The price is 11.025.985 ₫
12.404.233 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Weatherstation Inn
Outdoor pool, pool loungers
Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
4.0 star property
Historic Seaport, 11 km from Key West National Wildlife Refuge
9.2 out of 10, Wonderful, (1008)
"Location, large rooms"
United States
george
The price is 13.692.107 ₫
17.447.852 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Ocean Key Resort - A Noble House Resort
View from property
Duval House

Duval House

Duval House
3.0 star property
Downtown Key West, 11.7 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (1003)
"I loved this place the location was absolutely perfect "
United States
Frank
The price is 6.556.917 ₫
7.942.692 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Duval House
Exterior
Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
3.5 star property
Uptown - Upper Duval, 11.8 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (1003)
"Staff awesome, good breakfast great location"
United States
Carin helen
The price is 10.229.054 ₫
11.507.685 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Orchid Key Inn - Adults Only
Exterior
Coco Plum Inn

Coco Plum Inn

Coco Plum Inn
3.0 star property
Downtown Key West, 11.4 km from Key West National Wildlife Refuge
9.6 out of 10, Exceptional, (468)
"Love the place convenient, clean and really nice"
United States
Matthew
The price is 8.265.542 ₫
9.298.932 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Coco Plum Inn
Outdoor pool, pool loungers
The Conch House Heritage Inn

The Conch House Heritage Inn

The Conch House Heritage Inn
3.5 star property
Old Town Key West, 12 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (145)
"Fantastic location "
United States
ANDREW
The price is 8.753.422 ₫
9.847.600 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
The Conch House Heritage Inn
Private beach, white sand, sun-loungers, beach umbrellas
Pier House Resort & Spa

Pier House Resort & Spa

Pier House Resort & Spa
4.0 star property
Historic Seaport, 11 km from Key West National Wildlife Refuge
9.0 out of 10, Wonderful, (1011)
"Lovely hotel, great room and ideal location."
United States
Donald
Pier House Resort & Spa
Exterior
La Concha Key West, Autograph Collection

La Concha Key West, Autograph Collection

La Concha Key West, Autograph Collection
4.0 star property
Historic Seaport, 11.3 km from Key West National Wildlife Refuge
9.0 out of 10, Wonderful, (295)
"Very nice staff! Clean hotel! "
United States
Tabitha Hall
The price is 8.926.887 ₫
10.931.487 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
La Concha Key West, Autograph Collection
11 Gecko's Garden - Adults Only | Premium bedding, pillow-top beds, individually decorated
Tropical Inn

Tropical Inn

Tropical Inn
3.5 star property
Downtown Key West, 11.7 km from Key West National Wildlife Refuge
9.6 out of 10, Exceptional, (364)
"Nice place to stay "
United States
yulio
The price is 8.818.683 ₫
10.579.157 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Tropical Inn
Outdoor pool
Silver Palms Inn

Silver Palms Inn

Silver Palms Inn
3.5 star property
Old Town Key West, 12.2 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (1008)
"We had a wonderful stay and it was a convenient location for all the activities along Duval Street. The room was clean & comfortable with a great breakfast."
United States
Susanne
The price is 6.015.609 ₫
8.543.955 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Silver Palms Inn
Front of property – evening/night
Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
4.0 star property
Old Town Key West, 11 km from Key West National Wildlife Refuge
9.2 out of 10, Wonderful, (1027)
"Our stay was great!"
United States
Richard
The price is 11.025.985 ₫
13.440.650 ₫ total
includes taxes & fees
19 Jan - 20 Jan 2026
Opal Key Resort & Marina, Key West
3 outdoor pools, a heated pool, pool loungers
Ambrosia Key West

Ambrosia Key West

Ambrosia Key West
3.5 star property
Old Town Key West, 11.6 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (1002)
"Great place to stay"
United States
Melody
The price is 8.030.022 ₫
9.033.775 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Ambrosia Key West
Fountain
Island City House Hotel

Island City House Hotel

Island City House Hotel
3.0 star property
Historic Seaport, 11.7 km from Key West National Wildlife Refuge
9.6 out of 10, Exceptional, (1003)
"Excellent stay"
United States
Emily Barbara
The price is 10.546.367 ₫
11.864.662 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Island City House Hotel
Front of property
Key West Villas

Key West Villas

Key West Villas
3.5 star property
Downtown Key West, 11.6 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (247)
"Awsome staff great location "
United States
Jeffrey
Key West Villas
Terrace/patio
Caribbean House

Caribbean House

Caribbean House
3.0 star property
Bahama Village, 11.4 km from Key West National Wildlife Refuge
9.2 out of 10, Wonderful, (289)
"Very nice and would stay again. It was close to a few of our favorite restaurants "
United States
Leonard Frisch
The price is 8.702.759 ₫
10.448.479 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Caribbean House
3 outdoor pools, pool umbrellas, pool loungers
The Marker Key West Harbor Resort

The Marker Key West Harbor Resort

The Marker Key West Harbor Resort
4.0 star property
Historic Seaport, 11.6 km from Key West National Wildlife Refuge
9.2 out of 10, Wonderful, (1005)
"Perfect location.. close to the wharf for the best dining experience."
United States
Marty
The price is 8.336.370 ₫
11.037.395 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
The Marker Key West Harbor Resort
Lobby sitting area
Westwinds Inn

Westwinds Inn

Westwinds Inn
3.5 star property
Historic Seaport, 11.9 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (1003)
"Great location and loved the heated pool!"
United States
Tammy
Westwinds Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Key West National Wildlife Refuge Hotel Reviews

Hyatt Vacation Club at Sunset Harbor, Key West

Hyatt Vacation Club at Sunset Harbor, Key West

10/10 Excellent
"Great location and staff was friendly. The pool area was perfect. "
Deborah 6-night trip
Posted 2 days ago
Hyatt Vacation Club at Sunset Harbor, Key West

Hotels near other Key West National Wildlife Refuge attractions

Truman Beach

Why not spend a lazy afternoon at Truman Beach during your trip to Key West? Stroll along the seaside or discover the area's beautiful sunsets.
See properties
Fort Zachary Taylor Park, Key West. State Park in Florida, USA., Shutterstock ID 761867707, Purchase Order: SP-1891 Wave 0, Client/Licensee: Hotels.com

Fort Zachary Taylor Historic State Park

4.4/5 (1,160 reviews)
Enjoy a trip to Fort Zachary Taylor Historic State Park and popular activities such as boating in Key West. Discover the area's beautiful sunsets or seek out its cycling trails.
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Frequently asked questions

What's the area like around Key West National Wildlife Refuge?
Key West National Wildlife Refuge is located in an area of Key West known for its bar scene, cycling and lively festivals. Key West is home to 2776 hotels and other accommodation options, so you can find something that's perfect for your stay.
If I need to cancel the hotel reservation for my stay near Key West National Wildlife Refuge, will I receive a refund?
Yes, the majority of room reservations are refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within 24 hours of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to view the best deals available near Key West National Wildlife Refuge.