Search Hotels Near Key West National Wildlife Refuge, Key West

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21 Dec - 22 Dec
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Our top choices for Key West National Wildlife Refuge hotels

Queen Deluxe ADA | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds
Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
3.5 star property
Downtown Key West, 11.8 km from Key West National Wildlife Refuge
10.0 out of 10, Exceptional, (1002)
"Great location, spotless rooms, attentive and friendly staff, great value."
United States
David
The price is 9.523.398 ₫
10.713.822 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Almond Tree Inn Hotel - Adults Only
King Room D | Balcony
Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages
2.5 star property
Historic Seaport, 11.4 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (882)
"The staff was really nice"
United States
doug
The price is 8.657.635 ₫
9.739.840 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Simonton Court Historic Inn & Cottages
Carriage House | Terrace/patio
The Gardens Hotel

The Gardens Hotel

The Gardens Hotel
4.0 star property
Downtown Key West, 11.6 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (1001)
"Amazing hotel, the perfect Key West vibe. Clean rooms, delicious breakfast. We will come back again"
United States
Isis
The price is 11.812.145 ₫
13.288.664 ₫ total
includes taxes & fees
22 Dec - 23 Dec
The Gardens Hotel
Exterior
The Marquesa Hotel

The Marquesa Hotel

The Marquesa Hotel
3.5 star property
Historic Seaport, 11.5 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (1000)
"Perfect place to stay. "
United States
Paulette
The price is 13.920.635 ₫
17.141.065 ₫ total
includes taxes & fees
22 Dec - 23 Dec
The Marquesa Hotel
Exterior
Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
3.5 star property
Uptown - Upper Duval, 11.8 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (1000)
"Staff awesome, good breakfast great location"
United States
Carin helen
The price is 9.523.398 ₫
10.713.822 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Orchid Key Inn - Adults Only
Outdoor pool, pool loungers
The Conch House Heritage Inn

The Conch House Heritage Inn

The Conch House Heritage Inn
3.5 star property
Old Town Key West, 12 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (145)
"Fantastic location "
United States
ANDREW
The price is 9.037.624 ₫
10.167.327 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
The Conch House Heritage Inn
Exterior
Coco Plum Inn

Coco Plum Inn

Coco Plum Inn
3.0 star property
Downtown Key West, 11.4 km from Key West National Wildlife Refuge
9.6 out of 10, Exceptional, (467)
"Love the place convenient, clean and really nice"
United States
Matthew
The price is 8.028.707 ₫
9.032.624 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Coco Plum Inn
Deluxe Suite, 1 King Bed, Private Pool | View from room
H2O Suites - Adults Only

H2O Suites - Adults Only

H2O Suites - Adults Only
3.5 star property
Uptown - Upper Duval, 12.1 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (581)
"Great place!!"
United States
Joel
The price is 11.552.285 ₫
14.772.583 ₫ total
includes taxes & fees
23 Dec - 24 Dec
H2O Suites - Adults Only
11 Gecko's Garden - Adults Only | Premium bedding, pillow-top beds, individually decorated
Tropical Inn

Tropical Inn

Tropical Inn
3.5 star property
Downtown Key West, 11.7 km from Key West National Wildlife Refuge
9.6 out of 10, Exceptional, (363)
"The place was excellent and the service amazing "
United States
Janae
The price is 6.458.754 ₫
7.923.973 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Tropical Inn
Signature Apartment, 1 Bedroom, Kitchen, Poolside (Room 17) | Terrace/patio
Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
3.5 star property
Old Town Key West, 12.2 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (134)
"We absolutely loved finding this gem to stay on our first visit to Key West. Great location, wonderful staff, and excellent room. "
United States
Sammy
Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
Premium bedding, iron/ironing board, free WiFi, bed sheets
Weatherstation Inn

Weatherstation Inn

Weatherstation Inn
2.5 star property
Truman Annex, 11 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (995)
"Wonderful property safe neighborhood convenient to all activities would stay here again."
United States
William
The price is 7.868.185 ₫
8.851.708 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Weatherstation Inn
Fountain
Island City House Hotel

Island City House Hotel

Island City House Hotel
3.0 star property
Historic Seaport, 11.7 km from Key West National Wildlife Refuge
9.6 out of 10, Exceptional, (1001)
"Excellent stay"
United States
Emily Barbara
The price is 8.999.730 ₫
10.124.697 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Island City House Hotel
Garden
Douglas House

Douglas House

Douglas House
3.0 star property
Uptown - Upper Duval, 11.9 km from Key West National Wildlife Refuge
9.6 out of 10, Exceptional, (229)
"We were very pleased with everything and great location."
United States
Lynn
The price is 5.817.843 ₫
7.199.581 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Douglas House
Front of property
L'Habitation Guest House

L'Habitation Guest House

L'Habitation Guest House
2.5 star property
Historic Seaport, 11.2 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (924)
"A great no hassle stay."
United States
Gary
The price is 4.616.177 ₫
5.193.265 ₫ total
includes taxes & fees
23 Dec - 24 Dec
L'Habitation Guest House
Outdoor pool, pool umbrellas, pool loungers
Marrero's Guest Mansion

Marrero's Guest Mansion

Marrero's Guest Mansion
3.5 star property
Downtown Key West, 11.3 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (335)
"Location very good Staff friendly Pool not well maintained Breakfast and happy hour lacking compared to others"
United States
Scott
The price is 8.552.375 ₫
9.621.553 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Marrero's Guest Mansion
View from property
Duval House

Duval House

Duval House
3.0 star property
Downtown Key West, 11.7 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (1001)
"I loved this place the location was absolutely perfect "
United States
Frank
The price is 5.221.689 ₫
6.440.173 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Duval House
3 outdoor pools, a heated pool, pool loungers
Ambrosia Key West

Ambrosia Key West

Ambrosia Key West
3.5 star property
Old Town Key West, 11.6 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (1001)
"Great location and clean room. Pool was relaxing; breakfast was good!"
United States
Jennifer
The price is 6.687.957 ₫
7.523.951 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Ambrosia Key West
Outdoor pool, pool loungers
Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
4.0 star property
Historic Seaport, 11 km from Key West National Wildlife Refuge
9.2 out of 10, Wonderful, (1006)
"Clean and spacious room, staff "
United States
Parikshit
The price is 13.682.747 ₫
17.435.923 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Ocean Key Resort - A Noble House Resort
Courtyard
Santa Maria Suites

Santa Maria Suites

Santa Maria Suites
4.0 star property
Uptown - Upper Duval, 12.2 km from Key West National Wildlife Refuge
9.6 out of 10, Exceptional, (1000)
"Awesome place we loved it"
United States
Josh
The price is 13.920.635 ₫
17.436.977 ₫ total
includes taxes & fees
13 Jan - 14 Jan 2026
Santa Maria Suites
Exterior
The Grand Guesthouse

The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West, 12.5 km from Key West National Wildlife Refuge
9.6 out of 10, Exceptional, (1000)
"Great stay"
United States
Ginger
The price is 6.420.439 ₫
7.880.869 ₫ total
includes taxes & fees
22 Dec - 23 Dec
The Grand Guesthouse
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Key West National Wildlife Refuge Hotel Reviews

Hyatt Vacation Club at Sunset Harbor, Key West

Hyatt Vacation Club at Sunset Harbor, Key West

10/10 Excellent
"Very clean, great location, nice staff, beautiful pool area."
Craig 2-night trip
Posted 8 days ago
Hyatt Vacation Club at Sunset Harbor, Key West

Hotels near other Key West National Wildlife Refuge attractions

Truman Beach

Why not spend a lazy afternoon at Truman Beach during your trip to Key West? Stroll along the seaside or discover the area's beautiful sunsets.
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Fort Zachary Taylor Park, Key West. State Park in Florida, USA., Shutterstock ID 761867707, Purchase Order: SP-1891 Wave 0, Client/Licensee: Hotels.com

Fort Zachary Taylor Historic State Park

4.4/5 (1,160 reviews)
Enjoy a trip to Fort Zachary Taylor Historic State Park and popular activities such as boating in Key West. Discover the area's beautiful sunsets or seek out its cycling trails.
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Frequently asked questions

What's the area like around Key West National Wildlife Refuge?
Key West National Wildlife Refuge is located in an area of Key West known for its bar scene, cycling and lively festivals. Key West is home to 2773 hotels and other accommodation options, so you can find something that's perfect for your stay.
If I need to cancel the hotel reservation for my stay near Key West National Wildlife Refuge, will I receive a refund?
Yes, the majority of room reservations are refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within 24 hours of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to view the best deals available near Key West National Wildlife Refuge.