Search Hotels Near Main Street Hyannis, Hyannis

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
26 Feb - 27 Feb
Tomorrow
27 Feb - 28 Feb
This weekend
27 Feb - 1 Mar
Next weekend
6 Mar - 8 Mar

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Main Street Hyannis hotels

Interior entrance

Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
3.0 star property
0.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (1,004 reviews)
"Very nice stay"
United States
Robert
The price is 3.083.951 ₫
4.276.362 ₫ total
includes taxes & fees
1 Mar - 2 Mar
Anchor In Distinctive Waterfront Lodging
Dining

Sea Street Inn

Sea Street Inn
4.0 star property
1.5 km from Main Street Hyannis
9.8 out of 10, Exceptional, (45 reviews)
"Very nicely renovated small property with a fantastic breakfast."
United States
Paul
The price is 6.153.547 ₫
7.042.842 ₫ total
includes taxes & fees
4 Mar - 5 Mar
Sea Street Inn
Indoor pool, seasonal outdoor pool

Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection
3.0 star property
1.9 km from Main Street Hyannis
9.2 out of 10, Wonderful, (115 reviews)
"Clean, nice staff, good amenities, central location"
United States
Malbis
The price is 3.072.205 ₫
3.639.027 ₫ total
includes taxes & fees
28 Feb - 1 Mar
Uncommoner Hotel by Reverie Boutique Collection
Indoor pool, seasonal outdoor pool

The Cove at Yarmouth by Westgate Resorts

The Cove at Yarmouth by Westgate Resorts
3.0 star property
2.1 km from Main Street Hyannis
9.2 out of 10, Wonderful, (253 reviews)
"Was unaware that pool facilities were closed for 2 weeks of maintenance which was primary purpose of stay"
United States
Edward
The price is 3.362.851 ₫
3.848.783 ₫ total
includes taxes & fees
12 Mar - 13 Mar
The Cove at Yarmouth by Westgate Resorts
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,000 reviews)
"They were excellent. Felt extremely comfortable. Their breakfast was amazing, staff were so friendly!"
United States
Linda
The price is 2.761.070 ₫
3.160.045 ₫ total
includes taxes & fees
15 Mar - 16 Mar
Hampton Inn & Suites Cape Cod-West Yarmouth
Indoor pool

Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis
3.0 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (493 reviews)
"Parking was free and easy, room was very clean and housekeeping service was top notch. "
United States
Maureen
The price is 3.554.048 ₫
4.067.607 ₫ total
includes taxes & fees
4 Mar - 5 Mar
Courtyard By Marriott Cape Cod Hyannis
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

Bayside Resort Hotel

Bayside Resort Hotel
3.0 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,559 reviews)
"The place was clean, staff very nice and a good breakfast! Nice pool and beach area."
United States
LisaAnn
The price is 2.440.537 ₫
3.092.043 ₫ total
includes taxes & fees
12 Mar - 13 Mar
Bayside Resort Hotel
Lobby

Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis
3.0 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (682 reviews)
"Excellent staff-clean rooms-great location"
United States
Patrice
The price is 3.210.546 ₫
3.674.470 ₫ total
includes taxes & fees
12 Mar - 13 Mar
Fairfield Inn & Suites by Marriott Cape Cod Hyannis
Free daily continental breakfast

Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel
2.5 star property
0.3 km from Main Street Hyannis
8.4 out of 10, Very good, (20 reviews)
"It was ok staff was nice"
United States
Troy
The price is 3.083.951 ₫
3.529.582 ₫ total
includes taxes & fees
29 Mar - 30 Mar
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
Exterior

Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis
4.0 star property
0.9 km from Main Street Hyannis
8.4 out of 10, Very good, (893 reviews)
"It was a decent stay I can’t complain "
United States
Rony
The price is 3.399.263 ₫
3.890.457 ₫ total
includes taxes & fees
21 Mar - 22 Mar
Doubletree by Hilton Cape Cod - Hyannis
Indoor pool

Courtyard Resort

Courtyard Resort
2.0 star property
0.3 km from Main Street Hyannis
8.2 out of 10, Very good, (61 reviews)
"It was ok. Best part was it was near everything. "
United States
Kimberly
The price is 2.845.118 ₫
3.256.237 ₫ total
includes taxes & fees
1 Mar - 2 Mar
Courtyard Resort
Free daily continental breakfast

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
0.3 km from Main Street Hyannis
8.0 out of 10, Very good, (1,000 reviews)
"Nice hotel had a perfect stay"
United States
David
The price is 2.459.591 ₫
2.815.002 ₫ total
includes taxes & fees
29 Mar - 30 Mar
Comfort Inn Hyannis - Cape Cod
Exterior

Cape Sands Inn

Cape Sands Inn
2.5 star property
1.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1,023 reviews)
"Room was nice and spacious, very clean. Upstairs people was a little loud but other than that the stay was good. Would definitely stay again. "
United States
Celestina
The price is 1.946.687 ₫
2.227.806 ₫ total
includes taxes & fees
1 Mar - 2 Mar
Cape Sands Inn
Exterior

Hyannis Harbor Hotel

Hyannis Harbor Hotel
3.5 star property
0.6 km from Main Street Hyannis
8.0 out of 10, Very good, (1,005 reviews)
"Lovely stay! One of the best hotels to stay in Hyannis. "
United States
Mary
The price is 3.261.445 ₫
4.786.722 ₫ total
includes taxes & fees
1 Mar - 2 Mar
Hyannis Harbor Hotel
Exterior

Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG
3.0 star property
2.9 km from Main Street Hyannis
8.2 out of 10, Very good, (990 reviews)
"Great place to stay "
United States
Lilian
The price is 2.975.628 ₫
3.405.606 ₫ total
includes taxes & fees
8 Mar - 9 Mar
Holiday Inn Hyannis by IHG
Exterior

Sea Breeze Inn

Sea Breeze Inn
2.5 star property
1.8 km from Main Street Hyannis
7.8 out of 10, Good, (193 reviews)
"Nice place to stay "
United States
Kevin
The price is 2.323.078 ₫
2.658.750 ₫ total
includes taxes & fees
27 Feb - 28 Feb
Sea Breeze Inn
Lobby

Hyannis Plaza Hotel

Hyannis Plaza Hotel
2.5 star property
0.9 km from Main Street Hyannis
7.0 out of 10, Good, (1,000 reviews)
"The best staff abd it was clean and beautiful "
United States
Heather
The price is 2.310.027 ₫
2.904.845 ₫ total
includes taxes & fees
1 Mar - 2 Mar
Hyannis Plaza Hotel
Family House, Private Bathroom, Pool View | Lounge

Sal's Place

Sal's Place
2.0 star property
2.5 km from Main Street Hyannis
The price is 10.440.800 ₫
15.081.736 ₫ total
includes taxes & fees
3 Mar - 4 Mar
Sal's Place
Front of property

The Village Inn Cape Cod

The Village Inn Cape Cod
3.5 star property
6.1 km from Main Street Hyannis
10.0 out of 10, Exceptional, (224 reviews)
"It was so charming, would definitely stay there again! "
United States
Kyle
The price is 5.350.910 ₫
6.124.312 ₫ total
includes taxes & fees
27 Feb - 28 Feb
The Village Inn Cape Cod
Front of property

Inn on Main

Inn on Main
3.5 star property
6.4 km from Main Street Hyannis
10.0 out of 10, Exceptional, (74 reviews)
"We love staying here! Best dog B&B in America!"
United States
Barbara
The price is 6.437.928 ₫
7.368.209 ₫ total
includes taxes & fees
1 Mar - 2 Mar
Inn on Main
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Main Street Hyannis

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Interior entrance
Anchor In Distinctive Waterfront Lodging
3.0 star property
9.4
Exceptional
1,004 reviews
View
Dining
Sea Street Inn
4.0 star property
9.8
Exceptional
45 reviews
View
Indoor pool, seasonal outdoor pool
Uncommoner Hotel by Reverie Boutique Collection
3.0 star property
9.2
Wonderful
115 reviews
View
Indoor pool, seasonal outdoor pool
The Cove at Yarmouth by Westgate Resorts
3.0 star property
9.2
Wonderful
253 reviews
View
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers
Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
8.8
Excellent
1,000 reviews
View

Top Main Street Hyannis Hotel Reviews

Bayside Resort Hotel

Bayside Resort Hotel

10/10 Excellent
"Clean and good size room, friendly staff, Expedia gold status perks, quiet on the 2nd floor, excellent complimentary breakfast"
Melissa 2-night trip
Posted 3 days ago
Bayside Resort Hotel

Hotels near other Main Street Hyannis attractions

John F. Kennedy Hyannis Museum showcases bronze statue and historic architecture in Hyannis Massachusetts

John F. Kennedy Hyannis Museum

4.4/5 (259 reviews)
You can spend an afternoon studying the exhibits at John F. Kennedy Hyannis Museum during your travels in Hyannis. Wander through the beautiful beaches and waterfront in this family-friendly area.
See properties
Cape Cod Maritime Museum which includes a bay or harbor and signage

Cape Cod Maritime Museum

You can spend an afternoon studying the exhibits at Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the waterfront in this family-friendly area or visit its seafood restaurants.
See properties

Frequently asked questions

What's the area like around Main Street Hyannis?
Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 187 hotels and other accommodation options you'll find within a mile.
How many hotels can I expect to find near Main Street Hyannis?
Expedia has 187 hotels and other accommodation options within a mile from Main Street Hyannis.
If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis.
What can I see and do near Main Street Hyannis?
John F. Kennedy Hyannis Museum, Whydah Pirate Museum and Cape Cod Maritime Museum feature captivating exhibits. Hyannis Harbor, Edward Gorey House and Sandy Neck Lighthouse are landmarks that you won't want to miss. You can enjoy live performances at Cape Cod Melody Tent and Barnstable Performing Arts Center.