Search Hotels in Medical Center District, San Antonio

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Our top choices for Medical Center District hotels

San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,020 reviews)
"Perfect place to stay comfy and clean delicious food good staff thank you much."
United States
Iris Grisell
The price is 2.665.100 ₫
3.166.986 ₫ total
includes taxes & fees
18 Apr - 19 Apr
San Antonio Marriott Northwest Medical Center

Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,000 reviews)
"Clean, helpful staff. "
United States
Edna
The price is 2.582.104 ₫
3.052.279 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Courtyard by Marriott Medical Center San Antonio

Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,003 reviews)
"clean room staff was very friendly, breakfast was amazing!!"
United States
Drew
The price is 2.608.452 ₫
3.045.367 ₫ total
includes taxes & fees
30 Mar - 31 Mar
Fairfield Inn & Suites by Marriott San Antonio Medical Center

OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.2 out of 10, Good, (229 reviews)
"Staff was courteous and professional and the room is nice."
United States
Thomas
The price is 1.528.184 ₫
1.968.591 ₫ total
includes taxes & fees
26 Mar - 27 Mar
OYO Inn & Suites Medical Center San Antonio

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,293 reviews)
"Had a great stay. "
United States
MARY
The price is 2.371.057 ₫
2.802.804 ₫ total
includes taxes & fees
1 Apr - 2 Apr
Drury Inn & Suites San Antonio Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (261 reviews)
"This Hotel is well lit and we felt safe. The staff was outstanding during check in and check out! Room was very clean. We had a very comfortable stay. "
United States
Gilbert
The price is 1.235.985 ₫
1.442.817 ₫ total
includes taxes & fees
26 Mar - 27 Mar
Studio 6 San Antonio, Tx - Northwest Medical Center

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3,232 reviews)
"Clean room, comfortable beds, awesome breakfast. The stay was great "
United States
VERNA
The price is 2.160.536 ₫
2.553.912 ₫ total
includes taxes & fees
23 Apr - 24 Apr
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Park Inn by Radisson

Park Inn by Radisson
2.0 star property
Medical Center District
7.2 out of 10, Good, (1,000 reviews)
"Room was spotless and bed was great."
United States
Pamela
The price is 1.687.589 ₫
1.970.261 ₫ total
includes taxes & fees
8 Apr - 9 Apr
Park Inn by Radisson

Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.0 out of 10, (514 reviews)
"It was a comfortable stay. No roaches or bed bugs at affordable prices "
United States
FrankR
The price is 1.114.520 ₫
1.317.463 ₫ total
includes taxes & fees
26 Mar - 27 Mar
Flex Studios

Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (1,000 reviews)
"Room was clean, beds comfortable, staff extremely friendly and helpful "
United States
Kathleen
The price is 1.251.267 ₫
1.479.177 ₫ total
includes taxes & fees
26 Mar - 27 Mar
Motel 6 San Antonio, TX - Northwest Medical Center

Studio 6 Extended Stay - San Antonio, TX - Medical Center

Studio 6 Extended Stay - San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (846 reviews)
"Good place to stay "
United States
fidel
The price is 1.119.527 ₫
1.375.893 ₫ total
includes taxes & fees
26 Mar - 27 Mar
Studio 6 Extended Stay - San Antonio, TX - Medical Center

Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.6 out of 10, Good, (284 reviews)
"Yes .staff really nice "
United States
jamar
Atria Inn & Suites

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX
3.0 star property
Medical Center District
6.8 out of 10, (1,001 reviews)
"A good hotel choice. Had a good breakfast. "
United States
Kelsey
The price is 1.612.498 ₫
1.882.592 ₫ total
includes taxes & fees
19 Apr - 20 Apr
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
3.5 star property
Far West Side, 11.3 km from Medical Center District
9.0 out of 10, Wonderful, (1,525 reviews)
"Great place"
United States
Jonatan
The price is 3.888.965 ₫
5.685.635 ₫ total
includes taxes & fees
6 Apr - 7 Apr
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Extended Stay America Premier Suites - San Antonio - Schertz

Extended Stay America Premier Suites - San Antonio - Schertz
2.5 star property
29.4 km from Medical Center District
9.0 out of 10, Wonderful, (232 reviews)
"The room was very clean and staff was great"
United States
Eda
The price is 2.608.189 ₫
2.999.457 ₫ total
includes taxes & fees
26 Mar - 27 Mar
Extended Stay America Premier Suites - San Antonio - Schertz

Plaza San Antonio Hotel & Spa, Autograph Collection

Plaza San Antonio Hotel & Spa, Autograph Collection
4.0 star property
Downtown San Antonio, 12.9 km from Medical Center District
9.4 out of 10, Exceptional, (762 reviews)
"Great place would recommend to anyone "
United States
Jonathan
The price is 4.242.028 ₫
5.839.943 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Plaza San Antonio Hotel & Spa, Autograph Collection

Spark by Hilton San Antonio Dominion

Spark by Hilton San Antonio Dominion
3.0 star property
19.5 km from Medical Center District
8.8 out of 10, Excellent, (333 reviews)
"Great place to stay"
United States
Ketan
The price is 1.814.850 ₫
1.955.501 ₫ total
includes taxes & fees
1 Apr - 2 Apr
Spark by Hilton San Antonio Dominion

Best Western Garden Inn

Best Western Garden Inn
2.5 star property
Uptown, 21.2 km from Medical Center District
8.2 out of 10, Very good, (1,000 reviews)
"Friendly Staff, easily find location,"
United States
Hua
The price is 1.903.380 ₫
2.222.195 ₫ total
includes taxes & fees
9 Apr - 10 Apr
Best Western Garden Inn

Hampton Inn & Suites Schertz

Hampton Inn & Suites Schertz
2.5 star property
31.1 km from Medical Center District
8.8 out of 10, Excellent, (860 reviews)
"The room was clean and affordable "
United States
Tamara
The price is 2.299.390 ₫
2.644.299 ₫ total
includes taxes & fees
6 Apr - 7 Apr
Hampton Inn & Suites Schertz

stayAPT Suites San Antonio-Randolph

stayAPT Suites San Antonio-Randolph
2.5 star property
Live Oak, 24.4 km from Medical Center District
8.8 out of 10, Excellent, (513 reviews)
"Great stay "
United States
Robert
stayAPT Suites San Antonio-Randolph
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Medical Center District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Lobby
Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
9.0
Wonderful
1,003 reviews
View
Lobby
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.2
Wonderful
1,293 reviews
View
Lobby
San Antonio Marriott Northwest Medical Center
3.5 star property
8.6
Excellent
1,020 reviews
View
Bar (on property)
Courtyard by Marriott Medical Center San Antonio
3.0 star property
8.8
Excellent
1,000 reviews
View
Free daily buffet breakfast
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
8.4
Very good
3,232 reviews
View

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio

A scenic riverfront great entertainment and top sights from Aztec Theater to San Antonio River – discover Downtown San Antonio, a destination also famous for its historic sites.

Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum are top sights worth seeing.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista while you're in town.

Midtown

Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or The DoSeum while you're exploring the area.

Top Medical Center District Hotel Reviews

Frequently asked questions

What is Medical Center District like?
Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Are you looking for Medical Center District travel tips? Make sure that you visit USAA Corporate Office Headquarters and The San Antonio Art Institute while you're in the neighbourhood.
How many hotels will I be able to find in Medical Center District?
Expedia has 121 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.
What can I see and do in this San Antonio neighbourhood?
USAA Corporate Office Headquarters, The San Antonio Art Institute and Cinemark San Antonio 16 are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.