Search Hotels in Medicine Lake, Minneapolis - St. Paul

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Our top choices for Medicine Lake hotels

Radisson Blu Mall of America

Radisson Blu Mall of America
4.5 star property
21.5 km from Medicine Lake
9.0 out of 10, Wonderful, (2728)
"Great rooms, staff, location, etc"
United States
Adela
The price is 5.122.215 ₫
5.943.049 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Radisson Blu Mall of America

Staybridge Suites Minneapolis-Bloomington by IHG

Staybridge Suites Minneapolis-Bloomington by IHG
3.0 star property
16.9 km from Medicine Lake
9.2 out of 10, Wonderful, (1002)
"All of the above we love this hotel."
United States
Gregory
The price is 2.885.440 ₫
3.347.795 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Staybridge Suites Minneapolis-Bloomington by IHG

Quality Inn & Suites Arden Hills - Saint Paul North

Quality Inn & Suites Arden Hills - Saint Paul North
2.5 star property
22.3 km from Medicine Lake
8.8 out of 10, Excellent, (1000)
"Been lodging here for several years for an annual trip. The property is consistent with being well-managed"
United States
Brian
The price is 1.990.730 ₫
2.217.176 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Quality Inn & Suites Arden Hills - Saint Paul North

Hilton Garden Inn Minneapolis/Bloomington

Hilton Garden Inn Minneapolis/Bloomington
3.0 star property
16.7 km from Medicine Lake
8.8 out of 10, Excellent, (1000)
"Great place to stay!!"
United States
Theresa
The price is 2.005.992 ₫
2.327.453 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Garden Inn Minneapolis/Bloomington

Hampton Inn Minneapolis Bloomington West

Hampton Inn Minneapolis Bloomington West
2.5 star property
16.8 km from Medicine Lake
9.2 out of 10, Wonderful, (1001)
"Great breakfast, friendly and helpful staff, decent sized pool, well maintained, nice bathroom, comfy beds."
United States
Christina
The price is 2.371.529 ₫
2.751.566 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hampton Inn Minneapolis Bloomington West

SpringHill Suites Minneapolis-St Paul Airpt/Mall of America

SpringHill Suites Minneapolis-St Paul Airpt/Mall of America
3.0 star property
21.3 km from Medicine Lake
9.0 out of 10, Wonderful, (1002)
"Clean room, good staff, breakfast was good. "
United States
Jerrel
The price is 2.344.667 ₫
2.720.401 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
SpringHill Suites Minneapolis-St Paul Airpt/Mall of America

Homewood Suites by Hilton Minneapolis-Mall Of America

Homewood Suites by Hilton Minneapolis-Mall Of America
3.0 star property
21.7 km from Medicine Lake
8.8 out of 10, Excellent, (1001)
"Staff were great, breakfast was good. "
United States
Maxine
The price is 2.567.818 ₫
2.979.311 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Homewood Suites by Hilton Minneapolis-Mall Of America

Embassy Suites by Hilton Minneapolis Airport

Embassy Suites by Hilton Minneapolis Airport
4.0 star property
21.9 km from Medicine Lake
9.0 out of 10, Wonderful, (1855)
"Great place to stay"
United States
Melissa
The price is 2.635.032 ₫
3.057.295 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Embassy Suites by Hilton Minneapolis Airport

Hyatt House Mall Of America Msp Airport

Hyatt House Mall Of America Msp Airport
2.5 star property
22 km from Medicine Lake
8.6 out of 10, Excellent, (1701)
"Nice property, bar, breakfast, shuttle "
United States
Neil
The price is 2.552.555 ₫
2.961.601 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Hyatt House Mall Of America Msp Airport

Renaissance Minneapolis Bloomington Hotel

Renaissance Minneapolis Bloomington Hotel
3.5 star property
16.8 km from Medicine Lake
9.2 out of 10, Wonderful, (1002)
"Excellent stay!"
United States
Kathleen
The price is 2.547.687 ₫
2.955.953 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Renaissance Minneapolis Bloomington Hotel

Home2 Suites by Hilton Minneapolis Mall of America

Home2 Suites by Hilton Minneapolis Mall of America
3.0 star property
21.8 km from Medicine Lake
9.4 out of 10, Exceptional, (1002)
"Excellent room, and great breakfast with variety."
Canada
Timothy
The price is 2.459.926 ₫
2.854.128 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Home2 Suites by Hilton Minneapolis Mall of America

Holiday Inn : Bloomington W MSP Airport Area by IHG

Holiday Inn : Bloomington W MSP Airport Area by IHG
3.0 star property
16.8 km from Medicine Lake
8.8 out of 10, Excellent, (1001)
"Excellent stay"
Canada
Sajan
The price is 1.657.845 ₫
1.923.513 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Holiday Inn : Bloomington W MSP Airport Area by IHG

Fairfield Inn & Suites by Marriott Minneapolis Bloomington/Mall of America

Fairfield Inn & Suites by Marriott Minneapolis Bloomington/Mall of America
2.5 star property
21.2 km from Medicine Lake
8.6 out of 10, Excellent, (1004)
"Location, staff were accommodating and nice "
United States
Florian Marie
The price is 2.105.200 ₫
2.442.559 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Fairfield Inn & Suites by Marriott Minneapolis Bloomington/Mall of America

Hampton Inn Suites Minneapolis St Paul Arpt-Mall of America

Hampton Inn Suites Minneapolis St Paul Arpt-Mall of America
2.5 star property
21.5 km from Medicine Lake
8.4 out of 10, Very good, (1002)
"Very nice hotel, great room and convenient location!"
United States
Claudia
The price is 2.309.668 ₫
2.679.792 ₫ total
includes taxes & fees
13 Jan - 14 Jan 2026
Hampton Inn Suites Minneapolis St Paul Arpt-Mall of America

AC Hotel Bloomington Mall of America

AC Hotel Bloomington Mall of America
3.0 star property
21.4 km from Medicine Lake
9.4 out of 10, Exceptional, (1002)
"Easy and simple check in. Very clean and comfortable rooms."
United States
Sidney
The price is 3.342.005 ₫
3.877.562 ₫ total
includes taxes & fees
10 Jan - 11 Jan 2026
AC Hotel Bloomington Mall of America

SpringHill Suites by Marriott St. Paul Arden Hills

SpringHill Suites by Marriott St. Paul Arden Hills
2.5 star property
22.2 km from Medicine Lake
9.4 out of 10, Exceptional, (623)
"Amazing place"
United States
Desses
The price is 2.105.200 ₫
2.344.667 ₫ total
includes taxes & fees
29 Dec - 30 Dec
SpringHill Suites by Marriott St. Paul Arden Hills

Comfort Inn & Suites St. Paul Northeast

Comfort Inn & Suites St. Paul Northeast
2.5 star property
28.9 km from Medicine Lake
8.2 out of 10, Very good, (1002)
"Staff was "
United States
Jada
The price is 2.709.392 ₫
2.936.303 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Comfort Inn & Suites St. Paul Northeast

Embassy Suites by Hilton Bloomington/Minneapolis

Embassy Suites by Hilton Bloomington/Minneapolis
3.5 star property
17.6 km from Medicine Lake
8.6 out of 10, Excellent, (1500)
"Was an incredible stay!"
United States
Carina
The price is 2.087.043 ₫
2.421.491 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Embassy Suites by Hilton Bloomington/Minneapolis

Courtyard by Marriott Bloomington by Mall of America

Courtyard by Marriott Bloomington by Mall of America
3.0 star property
20.1 km from Medicine Lake
8.8 out of 10, Excellent, (1001)
"Staff was excellent, facility was spotless and just felt fresh, and conveniently located by the airport and Mall of America. "
United States
Kevin
The price is 2.294.668 ₫
2.662.389 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Courtyard by Marriott Bloomington by Mall of America

Omni Viking Lakes Hotel

Omni Viking Lakes Hotel
4.0 star property
28.5 km from Medicine Lake
9.6 out of 10, Exceptional, (970)
"Excellent staff, clean rooms, and love the Kyndred Hearth restaurant!"
United States
Mitchell
The price is 3.978.828 ₫
4.421.446 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Omni Viking Lakes Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medicine Lake

Find the best Medicine Lake areas for the activities you enjoy most.

Downtown Minneapolis

Known for its fantastic nightlife and popular shops, there's plenty to explore in Downtown Minneapolis. Check out top attractions like U.S. Bank Stadium and Nicollet Mall, and jump on the metro at Nicollet Mall Station or Warehouse - Hennepin Station to see more of the city.

South Minneapolis

While you're in South Minneapolis, take in top sights like Parkway Theater or Lake Nokomis, and hop on the metro to see more of the city at 38th Street Station or 46th Street Station.

Downtown St. Paul

Travellers choose Downtown St. Paul for its great live music. Hop aboard the metro at 10th Street Station or Central Station and check out top sights like Fitzgerald Theater.

Downtown West

Enjoy the popular shops in Downtown West. Nicollet Mall is a worthwhile stop, and you can jump on the metro at Nicollet Mall Station or Government Plaza Station to see more of Minneapolis.

East Bloomington

While you're in East Bloomington, take in top sights like Mall of America or Nickelodeon Universe, and hop on the metro to see more of the city at Mall of America Station or 28th Avenue Station.

Top Medicine Lake Hotel Reviews

Frequently asked questions

What is Medicine Lake like?
Travellers are sure to enjoy a stay in Plymouth's Medicine Lake neighbourhood.
If I need to cancel my hotel reservation in Medicine Lake, will I receive a refund?
Yes, most room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the best deals in Medicine Lake.
What can I see and do in this Plymouth neighbourhood?
A few places to visit in the area around Medicine Lake include French Park Beach, Sky Zone Indoor Trampoline Park and Plymouth Playhouse. When you're sightseeing in Plymouth, Brookview Golf Course and Ridgedale Center are also worth a stop.