Murphysboro Holidays
Book a Hotel + Flight or Car together to unlock savings
Photo by Southernmost Illinois Tourism Bureau
Top hotels in Murphysboro
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
120 MUDDY MONSTER ROAD Murphysboro IL
Fully refundable
The price is 2.553.428 ₫ per night from 26 Dec to 27 Dec
2.553.428 ₫
2.833.794 ₫ total
26 Dec - 27 Dec
includes taxes & fees
9.4/10 Exceptional! (512 reviews)
Everything was good
Reviewed on 13 Dec 2025
Drury Inn & Suites Marion
2706 W DeYoung St Marion IL
Fully refundableReserve now, pay when you stay
The price is 1.710.797 ₫ per night from 2 Jan to 3 Jan
1.710.797 ₫
2.052.746 ₫ total
2 Jan - 3 Jan 2026
includes taxes & fees
9.4/10 Exceptional! (1,000 reviews)
Clean room, good food
Reviewed on 16 Dec 2025
Baymont by Wyndham Marion
2608 W Main St Marion IL
Fully refundableReserve now, pay when you stay
The price is 1.925.601 ₫ per night from 16 Jan to 17 Jan
1.925.601 ₫
2.310.336 ₫ total
16 Jan - 17 Jan 2026
includes taxes & fees
8.2/10 Very Good! (1,072 reviews)
Great room!
Reviewed on 16 Dec 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
General John A. Logan Museum
You can spend time studying the exhibits at General John A. Logan Museum during your trip to Murphysboro. You can enjoy the cafes while in the area.
