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Check availability on Otay Business Hotels

Our top choices for Otay business-friendly hotels

Best Western Chula Vista/Otay Valley Hotel

Best Western Chula Vista/Otay Valley Hotel
2.5 star property
Otay
7.8 out of 10, Good, (1550)
"The breakfast was good there were healthy options. "
United States
Selene
The price is 2.662.673 ₫
2.928.941 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Chula Vista/Otay Valley Hotel

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1571)
"Loved our stay "
United States
Jeremy
The price is 3.269.441 ₫
5.150.861 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Hyatt Regency Mission Bay Spa and Marina

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
Mission Valley
7.8 out of 10, Good, (1003)
"Breakfast was delicious "
United States
Lukenson
The price is 2.327.042 ₫
2.685.812 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Crowne Plaza San Diego - Mission Valley by IHG

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (759)
"Friendly staff and clean rooms. "
Canada
Justine
The price is 2.886.650 ₫
3.346.926 ₫ total
includes taxes & fees
21 Dec - 22 Dec
The DEXTRO Little Italy, BW Premier Collection

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
El Cajon
9.2 out of 10, Wonderful, (1628)
"Very peaceful resort "
United States
Camilla
Sycuan Casino Resort

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
Harbor Island
8.4 out of 10, Very good, (3166)
"Great stay! "
United States
Melissa
The price is 2.796.925 ₫
4.162.590 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Sheraton San Diego Resort

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (2874)
"Great Location....tons of walking from the hotel Front desk were very nice and polite will be coming back for sure "
United States
Carlos
The price is 3.974.924 ₫
6.043.120 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Manchester Grand Hyatt San Diego

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1309)
"Room was super clean and updated, location up against the bay was perfect. We really enjoyed our stay and want to come back soon!"
United States
Haley
The price is 3.876.472 ₫
5.642.812 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
San Diego Mission Bay Resort

Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Fairfield Inn & Suites by Marriott San Diego Pacific Beach
2.5 star property
Pacific Beach
9.0 out of 10, Wonderful, (806)
"good place to stay"
United States
Sisi
The price is 2.711.372 ₫
3.116.587 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown
2.5 star property
Downtown San Diego
8.2 out of 10, Very good, (2290)
"The room was great, the bed was comfortable."
United States
PAM
The price is 2.634.793 ₫
3.054.910 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Hampton Inn San Diego-Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Otay Hotel Reviews

Frequently asked questions

Why book your business-friendly hotel in Otay with Expedia?
At Expedia, our top task is to help you choose a suitable stay at the right price. From 5-star corporate-friendly escapes to affordable hotels loaded with amenities, you'll have your next work trip arranged in a few quick clicks.
How can I find cheap business-friendly hotels in Otay?
Expedia can help you narrow your search for cheap business-friendly hotels in Otay. Simply go to the "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work productively and comfortably, like included breakfast and free WiFi. You can also choose your budget and preferred star rating to keep costs down.