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Check availability on Otay Business Hotels

Our top choices for Otay business-friendly hotels

Best Western Chula Vista/Otay Valley Hotel

Best Western Chula Vista/Otay Valley Hotel
2.5 star property
Otay
7.8 out of 10, Good, (1543)
"The breakfast was good there were healthy options. "
United States
Selene
The price is 2.660.953 ₫
2.927.049 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Best Western Chula Vista/Otay Valley Hotel

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1859)
"Enjoyed my stay"
United States
Brandon
The price is 2.584.663 ₫
4.287.631 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton San Diego Bayfront

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
Harbor Island
8.2 out of 10, Very good, (3177)
"Great stay! "
United States
Melissa
The price is 2.472.858 ₫
3.789.478 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Sheraton San Diego Resort

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1309)
"great stay! Food was great and my kids loved the pool and location"
United States
ANDREA
The price is 3.095.282 ₫
4.743.791 ₫ total
includes taxes & fees
14 Dec - 15 Dec
San Diego Mission Bay Resort

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
El Cajon
9.2 out of 10, Wonderful, (1631)
"Nice rooms. Great food at all restaurants "
United States
Steve
Sycuan Casino Resort

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (729)
"Great little boutique hotel ! Friendly staff as well"
Canada
Caroll
The price is 2.571.733 ₫
2.981.796 ₫ total
includes taxes & fees
14 Dec - 15 Dec
The DEXTRO Little Italy, BW Premier Collection

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
Mission Valley
7.8 out of 10, Good, (1004)
"Good value Nice place to stay "
United States
John
The price is 2.325.539 ₫
2.684.077 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Crowne Plaza San Diego - Mission Valley by IHG

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1570)
"Loved our stay "
United States
Jeremy
The price is 3.393.603 ₫
5.292.705 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Hyatt Regency Mission Bay Spa and Marina

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (2872)
"Great Location....tons of walking from the hotel Front desk were very nice and polite will be coming back for sure "
United States
Carlos
The price is 4.630.032 ₫
6.801.759 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Manchester Grand Hyatt San Diego

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley
2.5 star property
Mission Valley
8.8 out of 10, Excellent, (1279)
"Room was clean,buffet bkfast was good,staff were friendly & helpful!"
United States
Barry
The price is 2.483.381 ₫
2.854.522 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hampton Inn San Diego/Mission Valley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Otay Hotel Reviews

Frequently asked questions

Why book your business-friendly hotel in Otay with Expedia?
At Expedia, our top task is to help you choose a suitable stay at the right price. From 5-star corporate-friendly escapes to affordable hotels loaded with amenities, you'll have your next work trip arranged in a few quick clicks.
How can I find cheap business-friendly hotels in Otay?
Expedia can help you narrow your search for cheap business-friendly hotels in Otay. Simply go to the "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work productively and comfortably, like included breakfast and free WiFi. You can also choose your budget and preferred star rating to keep costs down.