The Best Hotels Closest to Oxbow Nature Center in Byron - 2026 Updated Prices

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Our top choices for Oxbow Nature Center hotels

A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.

A hotel lobby with leather sofas, a stone fireplace, and a patterned carpet.

A reception area with a wooden reception desk, a red doormat, and framed awards on the wall.

A hotel room with a large bed, a desk, a chair, a television, and a window with curtains.

1. Econo Lodge Mayo Clinic Area

18 km from Oxbow Nature Center

Ashley

1.830.005 ₫

2.106.794 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A modern dining area with high tables, chairs, and pendant lighting.

A swimming pool with a tiled deck, sun loungers, and a lifeguard chair.

A hotel room with two beds, a desk with a computer, a chair, and a window with a view.

A multi-story hotel with a modern design, featuring a prominent entrance with a covered area and a parking lot in front.

2. Hampton Inn & Suites Rochester-North

11.4 km from Oxbow Nature Center

Dr. Tim

2.535.811 ₫

2.919.353 ₫ total

includes taxes & fees

24 Oct - 25 Oct

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

A modern restaurant with a counter, seating area, and a TV screen.

A modern hotel room with a bed, desk, and kitchenette.

An indoor swimming pool with wooden ceiling beams, yellow chairs, and tables along the sides.

3. Home2 Suites by Hilton Rochester Mayo Clinic Area

16.7 km from Oxbow Nature Center

Vickie

3.175.092 ₫

3.655.324 ₫ total

includes taxes & fees

24 Oct - 25 Oct

A modern indoor patio with a fire feature, seating, and large windows.

A modern interior with a seating area, a bookshelf, and a window with a view of trees.

A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

A modern hotel lobby with a large glass wall, a green wall mural, and a seating area with sofas and chairs.

4. EVEN Hotel Rochester - Mayo Clinic Area by IHG

15.3 km from Oxbow Nature Center

Rici

3.170.414 ₫

4.001.218 ₫ total

includes taxes & fees

23 Oct - 24 Oct

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A modern living room with a stone fireplace, a blue armchair, a round coffee table, and a large window offering a view of the outdoors.

A breakfast bar with a wooden counter, a coffee machine, and a refrigerator.

5. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

14.4 km from Oxbow Nature Center

Jon

2.900.149 ₫

3.338.796 ₫ total

includes taxes & fees

17 Oct - 18 Oct

A swimming pool with clear blue water, surrounded by lounge chairs and a view of residential buildings through large windows.

A modern reception area with a brick-patterned wall, two reception desks, a flat-screen TV, and seating arrangements including a sofa and chairs.

A modern hotel with a flat roof, multiple windows, and a covered outdoor seating area.

A modern lounge area with seating, a fireplace, and a bar area.

6. Residence Inn by Marriott Rochester Mayo Clinic Area South

16.8 km from Oxbow Nature Center

Chee

3.560.219 ₫

4.098.701 ₫ total

includes taxes & fees

17 Oct - 18 Oct

A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.

A gym with various exercise equipment, including treadmills, stationary bikes, and weight machines.

A modern kitchen with a central island, bar stools, and pendant lighting. A living area with a sofa, ottoman, and a view of the outdoors is visible.

A hotel room with a kitchenette, a bed, a sofa, a small table, and a window with curtains.

7. Staybridge Suites Rochester - Mayo Clinic Area by IHG

15.3 km from Oxbow Nature Center

Sheri

2.780.609 ₫

3.253.149 ₫ total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.

A garden with a water feature, rocks, and yellow umbrellas.

A modern living room with a dark wall, a decorative light fixture, and a patterned wall art piece.

8. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

16.3 km from Oxbow Nature Center

Van

2.802.866 ₫

3.226.801 ₫ total

includes taxes & fees

10 Oct - 11 Oct

A Comfort Inn hotel with a stone facade, a covered entrance, and a parking area.

A modern dining area with wooden tables and chairs, a kitchen with granite countertops, and a view of the outdoors through large windows.

A spacious living room with a stone fireplace, blue sofas, and a flat-screen TV.

A hotel room with a blue sofa, a wooden coffee table, a bed with white linens, a TV, and a large mirror.

9. Comfort Inn & Suites West - Medical Center

11.4 km from Oxbow Nature Center

yuan

2.124.957 ₫

2.446.357 ₫ total

includes taxes & fees

10 Oct - 11 Oct

A hotel breakfast area with a self-serve station, including a waffle maker, toaster, and various food items.

A hotel lobby with a patterned carpet, two beige armchairs, a small table, a clock, a fire extinguisher, and a staircase.

A hotel room with a large bed, bedside tables, a mirror, and a patterned carpet.

A modern living room with a sofa, coffee table, and a TV mounted on a stone wall.

10. Quality Inn & Suites Mayo Clinic Area

17.8 km from Oxbow Nature Center

Edward

1.965.917 ₫

2.291.327 ₫ total

includes taxes & fees

24 Oct - 25 Oct

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern Hyatt House hotel with a prominent 'Hyatt House' sign, multiple floors, and a parking garage.

A modern dining area with round tables and chairs, a large painting on the wall, and a flat-screen TV mounted above a geometric-patterned wall.

A modern bar area with seating and a counter.

11. Hyatt House Rochester/Mayo Clinic Area

16.1 km from Oxbow Nature Center

Kathy

3.066.466 ₫

3.530.268 ₫ total

includes taxes & fees

17 Oct - 18 Oct

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

A coffee station with four coffee dispensers, a stack of disposable cups, and a tray with various coffee-related items.

A modern lounge area with seating arrangements, a reception desk, and a patterned wall.

A pool area with a table and chairs, a lifeguard chair, and a pool lift.

12. Hampton Inn Rochester-South

17.8 km from Oxbow Nature Center

dennis

2.748.905 ₫

3.164.677 ₫ total

includes taxes & fees

11 Oct - 12 Oct

A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

A modern interior with a large dining table, sofas, and a kitchen area.

A modern pool table in a spacious, well-lit room with large windows and a bar area.

A rooftop pool area with lounge chairs and umbrellas, surrounded by a modern building with a brick facade.

13. The Berkman

15 km from Oxbow Nature Center

Suzette

4.312.023 ₫

5.013.932 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A restaurant with wooden tables and bar stools, a bar area with a counter, and multiple televisions mounted on the walls.

An indoor swimming pool with a slide, seating area, and a large frog statue.

A modern kitchen with wooden cabinets, a microwave, an oven, and a dishwasher.

A hotel room with two beds, a desk, a chair, and a mirror.

14. AmericInn by Wyndham Rochester Near Mayo Clinic

17.6 km from Oxbow Nature Center

Jeanne

1.896.531 ₫

2.183.381 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A room with a fireplace, two leather armchairs, a sofa, and a large window providing a view of the outdoors.

A hotel room with a bed, a sink, a microwave, and a window with curtains.

A reception area with a curved counter, ceiling lights, and a potted plant.

A paved garden area with two benches, a potted plant with yellow flowers, and a variety of greenery.

15. Brentwood Inn & Suites

16 km from Oxbow Nature Center

Daniel

2.436.281 ₫

2.804.777 ₫ total

includes taxes & fees

29 Oct - 30 Oct

An indoor swimming pool with a wooden ceiling, clear blue water, and seating areas around the pool.

A café with multiple tables and chairs, a kitchen area with appliances, and a clock on the wall.

A coffee station with a coffee machine, cups, and a Bigelow tea display.

A wooden wardrobe with a television on top, a small black appliance, and a chair.

16. Med City Inn & Suites - Mayo Clinic Area

14.6 km from Oxbow Nature Center

Jose

1.855.472 ₫

2.136.111 ₫ total

includes taxes & fees

5 Oct - 6 Oct

A spacious lobby with a reception desk, sofas, and a coffee table.

A lobby with a brown sofa, yellow armchairs, a coffee table, and a clock on the wall.

A Sleep Inn hotel with a covered entrance, stone pillars, and a clear blue sky.

A hotel room with a large bed, a sofa, a TV, and a desk.

17. Sleep Inn & Suites West-Near Medical Center

11.3 km from Oxbow Nature Center

Jacqueline

2.242.938 ₫

2.582.181 ₫ total

includes taxes & fees

11 Oct - 12 Oct

A coffee shop interior with a wooden counter, menu boards, and seating area.

A hotel exterior with a 'Townplace Suites' sign, outdoor seating area, and 'OPEN' signage.

An outdoor seating area with tables and chairs, a neon sign, and flower arrangements.

18. TownePlace Suites by Marriott Rochester Mayo Clinic Area

15.9 km from Oxbow Nature Center

Hafsa

3.560.219 ₫

4.098.701 ₫ total

includes taxes & fees

17 Oct - 18 Oct

A Courtyard Marriott hotel with multiple floors, a brick facade, and illuminated signage.

A hotel room with a sofa, armchairs, a small kitchenette, a flat-screen TV, and a large window.

A modern living room with a sofa, a round coffee table, and a side table. There are large windows with a view of the outside.

A conference room with a long table, multiple chairs, and decorative wall art.

19. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

15 km from Oxbow Nature Center

MATTHEW

3.184.707 ₫

3.666.393 ₫ total

includes taxes & fees

10 Oct - 11 Oct

A modern living room with a flat-screen TV, a fireplace, comfortable seating, and a large window with a city view.

A modern hotel entrance with a glass facade, illuminated signage, and a covered walkway.

A modern hotel lobby with a curved staircase, seating areas, and large windows.

A spacious lobby with modern furniture, a spiral staircase, and large windows offering views of the outdoors.

20. Hilton Rochester Mayo Clinic Area

16.4 km from Oxbow Nature Center

Raymond

4.666.745 ₫

5.372.591 ₫ total

includes taxes & fees

17 Oct - 18 Oct

View all properties

Compare popular hotels close to Oxbow Nature Center

Property	Property class	Guest rating
Econo Lodge Mayo Clinic Area	9.0 Wonderful 1,000 reviews	View
Hampton Inn & Suites Rochester-North	9.2 Wonderful 1,005 reviews	View
Home2 Suites by Hilton Rochester Mayo Clinic Area	9.6 Exceptional 1,000 reviews	View
EVEN Hotel Rochester - Mayo Clinic Area by IHG	9.4 Exceptional 1,002 reviews	View
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys	9.6 Exceptional 740 reviews	View

Top Oxbow Nature Center Hotel Reviews

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

10/10 Excellent

"Nice rooms, very comfortable beds. Pool area looked fun for kids. We didn't have time to use the pool. Good breakfast. Courteous staff. Free shuttle to the Clinics. They made our first visit to the Mayo Clinic far less stressful."

Quality Inn near Medical Center

10/10 Excellent

"I had a nice room, although it was rather hot. But it has everything I needed, including quiet and privacy which really matter to me. Breakfast is good, but I don't eat pork so I do wish there was an alternative meat there. But the eggs were good and there was coffee, yogurt, muffins etc we which is really nice They were very accommodating and helpful too Yes I highly recommend them."

Kahler Grand Hotel

10/10 Excellent

"This is a grand hotel - stately, convenient and a delightful place to stay. Loved the walkable "subway" connecting the hotel to restaurants and Mayo Clinic. Enjoyed the Architecture and history of the Plummer Bldg."

Kahler Inn and Suites - Mayo Clinic Area

8/10 Good

"Overall it was a good stay. Pros: this hotel has the underground tunnel connected to the hospital so it was easy walking over, expecially since there is massive construction going on right there. Hotel was clean, staff was wonderful, breakfast was a good variety and good. Rooms were quiet, never heard any of the construction! A detail I may have missed or it wasn’t added in the description was if you parked in there ramp it was 17 dollars a night. Cons: defiantly needs some updating, but biggest con was the room we had was definitely not handicap accessible at all for the bathroom. Being “connect” to the hospital and the amount of the elderly I would think it would have something there. Toilet was so low almost ment for a child, and extremely tiny room, no grab bars, and step in shower/tub. I would stay here again, most definitely but not if I had elderly with me again"

Hampton Inn & Suites Rochester-North

8/10 Good

"J"

Sleep Inn & Suites West-Near Medical Center

10/10 Excellent

"Nice breakfast and staff. Good pricing"

Comfort Inn & Suites West - Medical Center

8/10 Good

"Everything was very good!"

Willow Inn Suites Rochester

10/10 Excellent

"Very friendly staff. No deposit for pets."

Other attractions near Oxbow Nature Center

Zollman Zoo

Visit the native and exotic animals who call Zollman Zoo home during your travels in Byron. Amble around the area's parks or experience its art scene.

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Oxbow Park

8.8/10 (5 reviews)

Explore the great outdoors at Oxbow Park, a lovely green space in Byron. Visit the cosy cafes or top-notch restaurants in this walkable area.

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Kalmar Town Hall

Kalmar Town Hall is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene.

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Putting Green

Enjoy a round of golf in Byron at Putting Green. Amble around the area's parks or experience its art scene.

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Somerby Golf Club

Enjoy a round of golf in Byron at Somerby Golf Club. Amble around the area's parks or experience its art scene.

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East Brookfield Park

After visiting East Brookfield Park, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.

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Somerby Park

Somerby Park is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene.

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Brook Lawn Park

After visiting Brook Lawn Park, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.

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Frequently asked questions

What's the area like around Oxbow Nature Center?

Oxbow Nature Center is located in Byron. You'll find 7 hotels and other accommodations within a few miles for a convenient home base.

How many hotels will I find near Oxbow Nature Center?

Expedia has 7 hotels and other accommodation options a few miles from Oxbow Nature Center.

If I need to cancel the hotel reservation for my stay near Oxbow Nature Center, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals available near Oxbow Nature Center.

What can I see and do near Oxbow Nature Center?

If you're looking forward to a day of shopping, consider Byron Town Square, Cheery Meadows Center and High Point Shopping Center and pick out the perfect souvenir. Putting Green, Somerby Golf Club and Links of Byron Mini Golf are worth a stop while you're in the area. Oxbow Park, Zollman Zoo and Kalmar Town Hall are a few additional nearby sights.

Search Hotels Near Oxbow Nature Center, Byron

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Our top choices for Oxbow Nature Center hotels

1. Econo Lodge Mayo Clinic Area

2. Hampton Inn & Suites Rochester-North

3. Home2 Suites by Hilton Rochester Mayo Clinic Area

4. EVEN Hotel Rochester - Mayo Clinic Area by IHG

5. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

6. Residence Inn by Marriott Rochester Mayo Clinic Area South

7. Staybridge Suites Rochester - Mayo Clinic Area by IHG

8. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

9. Comfort Inn & Suites West - Medical Center

10. Quality Inn & Suites Mayo Clinic Area

11. Hyatt House Rochester/Mayo Clinic Area

12. Hampton Inn Rochester-South

13. The Berkman

14. AmericInn by Wyndham Rochester Near Mayo Clinic

15. Brentwood Inn & Suites

16. Med City Inn & Suites - Mayo Clinic Area

17. Sleep Inn & Suites West-Near Medical Center

18. TownePlace Suites by Marriott Rochester Mayo Clinic Area

19. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

20. Hilton Rochester Mayo Clinic Area

Compare popular hotels close to Oxbow Nature Center

Top Oxbow Nature Center Hotel Reviews

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Quality Inn near Medical Center

Kahler Grand Hotel

Kahler Inn and Suites - Mayo Clinic Area

Hampton Inn & Suites Rochester-North

Sleep Inn & Suites West-Near Medical Center

Comfort Inn & Suites West - Medical Center

Willow Inn Suites Rochester

Other attractions near Oxbow Nature Center

Zollman Zoo

Oxbow Park

Kalmar Town Hall

Putting Green

Somerby Golf Club

East Brookfield Park

Somerby Park

Brook Lawn Park

Frequently asked questions