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Check availability on Panama City Luxury Hotels

Tonight
8 Dec - 9 Dec
Tomorrow
9 Dec - 10 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

Top Panama City Luxury Hotels

Exterior
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (554)
"Great hotel and location "
United Kingdom
Russell
The price is 10.795.649 ₫
11.875.214 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Sofitel Legend Casco Viejo, Panama City
Daily full breakfast for a fee
Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo

4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (257)
"Great location!"
United States
Erik
The price is 8.492.840 ₫
9.342.124 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Hotel La Compañía Casco Antiguo
4 outdoor pools, free pool cabanas, pool umbrellas
JW Marriott Panama

JW Marriott Panama

5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1005)
"Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel."
United States
Sarran
The price is 6.382.482 ₫
7.020.731 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
JW Marriott Panama
4 outdoor pools, open 8:00 AM to 8:00 PM, free pool cabanas
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4.0 star property
Veracruz
7.6 out of 10, Good, (1008)
"This one of the best vacation I ever had."
United States
CASSANDRA
The price is 7.170.736 ₫
7.170.736 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Dreams Playa Bonita Panama - All Inclusive
47-inch flat-screen TV with cable channels, TV
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4.0 star property
Casco Viejo
9.0 out of 10, Wonderful, (1004)
"Excellent hotel , good breakfast, great location, would highly recommend "
United States
Glen
The price is 5.326.108 ₫
5.858.719 ₫ total
includes taxes & fees
12 Dec - 13 Dec
Central Hotel Panama Casco Viejo
Suite, 1 Bedroom, Golf View (Terrace) | Premium bedding, minibar, in-room safe, desk
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (636)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is 6.109.625 ₫
6.720.588 ₫ total
includes taxes & fees
12 Dec - 13 Dec
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Front of property – evening/night
American Trade Hotel

American Trade Hotel

4.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (601)
"Excellent service and great rooms on a beautiful and historical building"
Canada
Manuel
The price is 7.687.451 ₫
8.456.196 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
American Trade Hotel
2 restaurants, local cuisine
W Panama

W Panama

5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1005)
"Clean room, great views, great staff!"
United States
Ashley
The price is 5.251.510 ₫
5.776.661 ₫ total
includes taxes & fees
19 Dec - 20 Dec
W Panama
3 outdoor pools, pool umbrellas, pool loungers
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

5.0 star property
Veracruz
8.0 out of 10, Very good, (1003)
"Clean rooms , friendly staff , had great experience "
United States
Saro
The price is 4.616.952 ₫
5.078.647 ₫ total
includes taxes & fees
17 Dec - 18 Dec
The Westin Playa Bonita Panama
Outdoor pool
Hilton Panama

Hilton Panama

5.0 star property
Bella Vista
8.8 out of 10, Excellent, (1001)
"Great place to stay."
United States
Salvador
The price is 4.907.472 ₫
5.398.219 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Hilton Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama City Hotel Reviews

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Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Panama City?
Arrange a flight into Panama City (PAC-Marcos A. Gelabert Intl.) Airport or Balboa (BLB-Panama Pacifico Intl.) Airport, and then treat yourself to a stay at one of 23 luxurious hotels. Known for its casinos and shopping, Panama City also has some interesting things to see and do including Albrook Shopping Mall, so you may want to take in the local sights during your visit.
How many luxury hotels should I expect to find in Panama City?
Lie in the lap of luxury during your getaway to Panama City in one of Expedia's 23 luxury hotels.
When can I expect good weather in Panama City?
Planning for the weather is a good way to make your trip to Panama City relaxing and enjoyable, especially when you're splurging. The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Panama City are July, August, June and November, with each month seeing an average of 369 mm of rainfall.
What's there to see and do in Panama City?
Experience Panama City and visit Albrook Shopping Mall, Via Espana and Iglesia del Carmen. If you have spare time during your trip, you might want to make a stop at Uruguay Street and Crown Casino.
How can I get around Panama City?
It's easier to get around town in style when you know your options. Walk to nearby metro stations such as Iglesia del Carmen Station, Vía Argentina and Santo Tomas Station. If you want to explore the larger area, hop on a train at Panama City Passenger Station.