Photo by Dean Moore

Search Holiday Rentals in Port Saint Lucie

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
9 Jan - 11 Jan
In two months
20 Feb - 22 Feb
In three months
20 Mar - 22 Mar
In four months
17 Apr - 19 Apr

Our top choices for Port Saint Lucie holiday rentals

Outdoor pool, pool umbrellas, pool loungers
Sheraton PGA Vacation Resort, Port St. Lucie

Holiday Home in Port Saint Lucie

Sheraton PGA Vacation Resort, Port St. Lucie
3.5 star property
9.0 out of 10, Wonderful, (646)
"Was very happy with our stay"
United States
matthew
The price is 3.739.286 ₫
4.188.001 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Sheraton PGA Vacation Resort, Port St. Lucie
Deluxe House, Pool View | Terrace/patio
The Poolside Escape Near Beaches

Villa in Floresta Gardens

The Poolside Escape Near Beaches
2.5 star property
The price is 6.556.917 ₫
12.215.352 ₫ total
includes taxes & fees
25 Dec - 26 Dec
The Poolside Escape Near Beaches
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Port Saint Lucie Hotel Reviews

Holiday Inn Express & Suites Port St. Lucie West by IHG

Holiday Inn Express & Suites Port St. Lucie West by IHG

10/10 Excellent
"Everything was very nice!"
Albert 1-night trip
Posted 3 days ago
Holiday Inn Express & Suites Port St. Lucie West by IHG

Frequently asked questions

Can I find a holiday rental in Port Saint Lucie?

Yes, there are holiday rentals in Port Saint Lucie close to Port St. Lucie Botanical Gardens, or you can select a more secluded option if you're looking for a relaxing stay. Tourists who visit Port Saint Lucie speak highly of the bustling port and array of shops. While you're in the area, you can also enjoy the top-notch restaurants and entertainment venues.

How many holiday rentals are there in Port Saint Lucie?

Expedia has 377 holiday rentals for your stay in Port Saint Lucie.

What can I see and do in Port Saint Lucie?

Family-friendly attractions include Superplay USA and Treasure Coast Model Railroads, whereas Port St. Lucie Botanical Gardens and River Park Marina are a couple of great spots to enjoy the outdoors. Other places in town to visit include The Saints at Port St. Lucie Golf Course and Clover Park.

What are holiday rentals like in Port Saint Lucie?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Port Saint Lucie. Holiday rentals offer extras such as patios, hot tubs and fire pits to help you enjoy your stay. If you're concerned about a clean environment, a holiday rental can offer a sense of privacy away from shared hotel lifts and lobbies bustling with people while still allowing you a great travel experience. You'll also find more space in a holiday rental than in a traditional hotel, which makes a holiday rental an attractive choice for a small group gathering.