Search Hotels in San Luis, Cali

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for San Luis hotels

Barranquilla residencia norte

Barranquilla residencia norte
2.0 star property
San Luis
The price is 5.010.300 ₫
5.010.300 ₫ total
18 Dec - 19 Dec
Barranquilla residencia norte

Sonesta Hotel Cali

Sonesta Hotel Cali
4.0 star property
Versalles, 5.4 km from San Luis
9.2 out of 10, Wonderful, (956)
"Yes the staff was very nice the food was delicius room sparkling and big I will stay again "
United States
Jolima
The price is 2.034.064 ₫
2.034.064 ₫ total
9 Jan - 10 Jan 2026
Sonesta Hotel Cali

Faranda Collection Cali, a member of Radisson Individuals

Faranda Collection Cali, a member of Radisson Individuals
4.0 star property
6.4 km from San Luis
8.8 out of 10, Excellent, (121)
"Friendly reception staff. Helpful manager. Very nice, clean property. Comfortable rooms. Quiet and peaceful, even though it's tight in the heart of the city. Breakfast was okay (the bread was not that fresh, but I guess it was no deal breaker. "
Canada
Burgess
The price is 1.577.466 ₫
1.577.466 ₫ total
13 Dec - 14 Dec
Faranda Collection Cali, a member of Radisson Individuals

Hotel Spiwak Chipichape Cali

Hotel Spiwak Chipichape Cali
4.5 star property
Chipichape, 4.8 km from San Luis
8.6 out of 10, Excellent, (1000)
"Great hotel, great location, great service"
United States
Mario
Hotel Spiwak Chipichape Cali

HOTEL 9.5 SAN FERNANDO

HOTEL 9.5 SAN FERNANDO
3.5 star property
Viejo San Fernando, 7.9 km from San Luis
9.0 out of 10, Wonderful, (26)
"Yes very welcoming "
United States
benjamin
HOTEL 9.5 SAN FERNANDO

Hotel Spirito by Spiwak

Hotel Spirito by Spiwak
3.5 star property
4.9 km from San Luis
8.4 out of 10, Very good, (738)
"Good place Good stuff Very clean room "
United States
Jairo
The price is 2.104.554 ₫
2.104.554 ₫ total
8 Jan - 9 Jan 2026
Hotel Spirito by Spiwak

ArisSha Boutique Hotel

ArisSha Boutique Hotel
2.5 star property
3.4 km from San Luis
9.8 out of 10, Exceptional, (9)
"Really nice hotel and good service"
United States
Jarol
The price is 1.013.619 ₫
1.013.619 ₫ total
13 Dec - 14 Dec
ArisSha Boutique Hotel

Movich Casa del Alferez

Movich Casa del Alferez
4.0 star property
Juanambú, 6 km from San Luis
9.2 out of 10, Wonderful, (588)
"It is a very nice place to stay, the food is great, the staff excellent, very polite."
United States
Julio
The price is 3.120.554 ₫
3.120.554 ₫ total
13 Dec - 14 Dec
Movich Casa del Alferez

Hotel el Peñón By Bithotels

Hotel el Peñón By Bithotels
4.0 star property
El Peñon, 7 km from San Luis
9.0 out of 10, Wonderful, (369)
"The room was clean and the staff was very helpful and courteous "
United States
Beatriz
The price is 1.487.862 ₫
1.487.862 ₫ total
13 Dec - 14 Dec
Hotel el Peñón By Bithotels

Hotel Estancia Chipichape Cali

Hotel Estancia Chipichape Cali
3.5 star property
La Flora, 4.3 km from San Luis
8.8 out of 10, Excellent, (146)
"Yes , great breakfast "
United States
Miryam
The price is 1.451.326 ₫
1.451.326 ₫ total
10 Jan - 11 Jan 2026
Hotel Estancia Chipichape Cali

TAMA Hotel Granada Real Cali

TAMA Hotel Granada Real Cali
3.0 star property
Granada, 5.7 km from San Luis
7.2 out of 10, Good, (107)
"It was amazing"
United States
Monica Smith
The price is 1.012.493 ₫
1.012.493 ₫ total
11 Jan - 12 Jan 2026
TAMA Hotel Granada Real Cali

Basic Hotel Chipichape By Hoteles MS

Basic Hotel Chipichape By Hoteles MS
3.0 star property
4.6 km from San Luis
7.0 out of 10, Good, (2)
"El desayunp adecuado "
Colombia
VLADIMIR
The price is 1.075.050 ₫
1.075.050 ₫ total
31 Dec - 1 Jan 2026
Basic Hotel Chipichape By Hoteles MS

Hotel Real Elim International

Hotel Real Elim International
2.5 star property
12 km from San Luis
9.0 out of 10, Wonderful, (288)
"Excellent location, nice room, professional staff. "
United States
Sandra
Hotel Real Elim International

Hotel Foresto 365

Hotel Foresto 365
4.0 star property
El Peñon, 7.1 km from San Luis
9.6 out of 10, Exceptional, (48)
"Staff was very nice."
United States
Maria
Hotel Foresto 365

BE Suites Hotel Cali

BE Suites Hotel Cali
3.0 star property
12 km from San Luis
8.6 out of 10, Excellent, (34)
"Good place "
United States
Henry Obando
The price is 1.638.414 ₫
1.638.414 ₫ total
27 Dec - 28 Dec
BE Suites Hotel Cali

Hampton by Hilton Cali, Colombia

Hampton by Hilton Cali, Colombia
3.5 star property
7.4 km from San Luis
9.0 out of 10, Wonderful, (610)
"Excellent place the staff is Really friendly and everything is nice and need very Clean Room"
United States
Angel
The price is 1.654.554 ₫
1.654.554 ₫ total
20 Dec - 21 Dec
Hampton by Hilton Cali, Colombia

HYPE STATES

HYPE STATES
3.5 star property
El Peñon, 7.3 km from San Luis
9.8 out of 10, Exceptional, (31)
"Cool place"
United States
Anthony
The price is 1.817.430 ₫
1.817.430 ₫ total
13 Dec - 14 Dec
HYPE STATES

Hotel Obelisco

Hotel Obelisco
4.0 star property
El Peñon, 7.2 km from San Luis
8.6 out of 10, Excellent, (482)
"I have been staying in this Hotel 4 times , this is my hometown and the location is perfect!"
United States
Viviana
The price is 1.508.121 ₫
1.508.121 ₫ total
13 Dec - 14 Dec
Hotel Obelisco

Park V Hotel & Suites

Park V Hotel & Suites
3.5 star property
4.8 km from San Luis
9.2 out of 10, Wonderful, (251)
"Exelent customer service "
United States
Alfredo L
Park V Hotel & Suites

Hotel Dann Cali

Hotel Dann Cali
3.0 star property
El Peñon, 6.9 km from San Luis
8.6 out of 10, Excellent, (557)
"Our stay at Hotel Dann was amazing. From the service to the delicious food, we had an exceptional experience and will suggest this hotel to friends and family. The room was clean, well maintained as well as every room we entered in the hotel. 5 stars! "
United States
Daisy
The price is 2.292.349 ₫
2.292.349 ₫ total
22 Dec - 23 Dec
Hotel Dann Cali
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Luis

Find the best San Luis areas for the activities you enjoy most.

Ciudad Jardín

Unique features of Ciudad Jardín include the restaurants and shopping. Make a stop by Palmas Mall or Las Velas Shopping Center while you're exploring the area.

Granada

Visitors to Granada enjoy its shopping, and if you want to do some exploring, Lugar a Dudas is worth a stop.

San Antonio

When in San Antonio, you can plan a visit to Centenario Commercial Center and Calima Gold Museum of the Bank of the Republic, some noteworthy sights in the nearby area.

El Peñon

While El Peñon may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Centenario Commercial Center and El Gato Del Rio.

Top San Luis Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What's it like in San Luis?
Travellers will be sure to find plenty to entertain them in Cali's San Luis neighbourhood.
If I need to cancel my hotel reservation in San Luis, will I receive a refund?
Yes! Most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of your booking. Add dates, click "Search", then use the "fully refundable" filter to view the best options available in San Luis.
What is there to do in this Cali neighbourhood?
Monument To Sport, Único Shopping Center and The Shopping Center Station are just a few of the places to visit in and around San Luis. While you're out sightseeing in Cali, make sure that you visit other sights such as Rio Cauca or Caña Aquapark.