Search Hotels in San Luis, Cali

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for San Luis hotels

Barranquilla residencia norte

Barranquilla residencia norte
2.0 star property
San Luis
The price is 4.999.850 ₫
4.999.850 ₫ total
27 Dec - 28 Dec
Barranquilla residencia norte

Osve Hotel Boutique

Osve Hotel Boutique
4.0 star property
8.2 km from San Luis
10.0 out of 10, Exceptional, (2)
"Everything was good. The room, breakfast, the swimming pool..."
Belgium
Katia
The price is 2.159.286 ₫
2.159.286 ₫ total
22 Dec - 23 Dec
Osve Hotel Boutique

hotel terraza San Antonio

hotel terraza San Antonio
3.0 star property
7.1 km from San Luis
10.0 out of 10, Exceptional, (4)
"Staff was very friendly and helpful. Room was very clean and hotel had great character "
United States
kurt
The price is 858.807 ₫
858.807 ₫ total
1 Jan - 2 Jan 2026
hotel terraza San Antonio

Mirago Hotel

Mirago Hotel
2.5 star property
2.9 km from San Luis
10.0 out of 10, Exceptional, (1)
"Excelente todo!"
Colombia
Michael
The price is 1.199.782 ₫
1.199.782 ₫ total
2 Jan - 3 Jan 2026
Mirago Hotel

Basic Hotel Chipichape By Hoteles MS

Basic Hotel Chipichape By Hoteles MS
3.0 star property
4.6 km from San Luis
7.0 out of 10, Good, (2)
"El desayunp adecuado "
Colombia
VLADIMIR
The price is 1.073.508 ₫
1.073.508 ₫ total
1 Jan - 2 Jan 2026
Basic Hotel Chipichape By Hoteles MS

Hotel Campestre El Molino Dapa Cali

Hotel Campestre El Molino Dapa Cali
3.0 star property
8.6 km from San Luis
7.2 out of 10, Good, (9)
"muy conforme con todo,la atencion,los cuartos,restaurante,el ambiente,la vista,"
United States
Hugo
The price is 1.656.270 ₫
1.656.270 ₫ total
25 Dec - 26 Dec
Hotel Campestre El Molino Dapa Cali

Ari Hotel

Ari Hotel
2.5 star property
10.8 km from San Luis
8.8 out of 10, Excellent, (20)
"Very responsive staff"
United States
Susan
The price is 1.100.718 ₫
1.100.718 ₫ total
22 Dec - 23 Dec
Ari Hotel

Hotel Arisha Cali

Hotel Arisha Cali
3.0 star property
10.9 km from San Luis
7.4 out of 10, Good, (3)
"The staff was very helpful, and accommodating to every request. Hotel is very clean! "
United States
Javier
The price is 1.840.300 ₫
1.840.300 ₫ total
23 Dec - 24 Dec
Hotel Arisha Cali

Hotel Imbanaco

Hotel Imbanaco
3.0 star property
9.2 km from San Luis
7.6 out of 10, Good, (97)
"Amazing all the staff!! Good place! But please eveday change the breakfast ty"
United States
Yolanda
The price is 1.308.658 ₫
1.308.658 ₫ total
21 Dec - 22 Dec
Hotel Imbanaco

Hotel El Alba

Hotel El Alba
3.0 star property
10 km from San Luis
8.6 out of 10, Excellent, (18)
"Experience was amazing. Customer service is great breakfast was delicious. Overall great experience, 100% recommend "
United States
eli
The price is 2.356.948 ₫
2.356.948 ₫ total
26 Dec - 27 Dec
Hotel El Alba

RECOVERY HOUSE BY ZENYA HOST

RECOVERY HOUSE BY ZENYA HOST
3.0 star property
9 km from San Luis
8.4 out of 10, Very good, (5)
"Address does not exist. SCAM"
United States
Jorge
The price is 945.932 ₫
945.932 ₫ total
22 Dec - 23 Dec
RECOVERY HOUSE BY ZENYA HOST

HGO HOTEL

HGO HOTEL
3.0 star property
9.2 km from San Luis
8.4 out of 10, Very good, (9)
"Wonderful, bright, clean with a great breakfast. "
United States
Angela
The price is 2.147.017 ₫
2.147.017 ₫ total
1 Jan - 2 Jan 2026
HGO HOTEL

Hotel Casa Kreenty

Hotel Casa Kreenty
3.0 star property
Viejo San Fernando, 8.1 km from San Luis
The price is 1.288.210 ₫
1.492.688 ₫ total
21 Dec - 22 Dec
Hotel Casa Kreenty

Hotel Eco Suite

Hotel Eco Suite
3.0 star property
11 km from San Luis
7.6 out of 10, Good, (27)
"For a 3 star hotel it was ok value"
United States
Reinerio
Hotel Eco Suite

Hotel Karlo

Hotel Karlo
3.0 star property
Viejo San Fernando, 8.2 km from San Luis
7.8 out of 10, Good, (49)
"Thank you all for your wonderful hospitality. See you again"
United States
Julia
Hotel Karlo

Malik Hotel Boutique

Malik Hotel Boutique
3.5 star property
Ciudad Jardín, 14.4 km from San Luis
8.4 out of 10, Very good, (76)
"Love the place it was an amazing stay"
United States
Juan
Malik Hotel Boutique

Hotel Elite

Hotel Elite
2.0 star property
6.7 km from San Luis
The price is 472.343 ₫
472.343 ₫ total
31 Dec - 1 Jan 2026
Hotel Elite

HOTEL HYM SAS

HOTEL HYM SAS
2.5 star property
21 km from San Luis
8.8 out of 10, Excellent, (3)
"Staff was friendly. The towels and linens were a bit dingy and the check in counter had a musty smell and a little disorganized. "
United States
Lucy
The price is 1.874.380 ₫
1.874.380 ₫ total
24 Dec - 25 Dec
HOTEL HYM SAS

Hotel Toscana Plaza

Hotel Toscana Plaza
3.0 star property
10.4 km from San Luis
7.8 out of 10, Good, (311)
"Good location and good food"
United States
Diego L
Hotel Toscana Plaza

Hotel Brisas de Calima

Hotel Brisas de Calima
2.5 star property
1.7 km from San Luis
8.2 out of 10, Very good, (38)
"Pretty good location, safe area, plenty of options for shopping, and eat. The staff are so wekconming and professional"
United States
Ingrid
The price is 742.259 ₫
742.259 ₫ total
25 Dec - 26 Dec
Hotel Brisas de Calima
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Luis

Find the best San Luis areas for the activities you enjoy most.

Ciudad Jardín

Unique features of Ciudad Jardín include the restaurants and shopping. Make a stop by Palmas Mall or Las Velas Shopping Center while you're exploring the area.

Granada

Visitors to Granada enjoy its shopping, and if you want to do some exploring, Lugar a Dudas is worth a stop.

San Antonio

When in San Antonio, you can plan a visit to Centenario Commercial Center and Calima Gold Museum of the Bank of the Republic, some noteworthy sights in the nearby area.

El Peñon

While El Peñon may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Centenario Commercial Center and Rock Park.

Top San Luis Hotel Reviews

Frequently asked questions

What's it like in San Luis?
Travellers will be sure to find plenty to entertain them in Cali's San Luis neighbourhood.
If I need to cancel my hotel reservation in San Luis, will I receive a refund?
Yes! Most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of your booking. Add dates, click "Search", then use the "fully refundable" filter to view the best options available in San Luis.
What is there to do in this Cali neighbourhood?
Monument To Sport, Único Shopping Center and The Shopping Center Station are just a few of the places to visit in and around San Luis. While you're out sightseeing in Cali, make sure that you visit other sights such as Rio Cauca or Caña Aquapark.

Explore a world of travel with Expedia