Photo by Samuel Romero

Search Hotels in Santa Clara, Seville

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
9 Dec - 10 Dec
Tomorrow
10 Dec - 11 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Clara hotels

Terrace/patio
Catalonia Híspalis

Catalonia Híspalis

3.0 star property
Santa Clara
7.4 out of 10, Good, (338)
"A lovely experience - the staff were courteous and the modern room was very clean. The breakfast which cost a little extra was delicious and the parking for a little extra was very secure. "
Canada
Gudrun
The price is 1.674.094 ₫
1.841.503 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Catalonia Híspalis
Deluxe Room, Terrace with Jacuzzi | Free minibar items, in-room safe, desk, laptop workspace
Hotel Murillo Reinoso

Hotel Murillo Reinoso

2.0 star property
Santa Cruz, 3.4 km from Santa Clara
9.6 out of 10, Exceptional, (57)
"Spacious room, clean, helpful staff."
United States
Cecilia
The price is 2.510.932 ₫
2.762.025 ₫ total
includes taxes & fees
10 Dec - 11 Dec
Hotel Murillo Reinoso
Outdoor pool
Ibis Styles Sevilla Santa Justa

Ibis Styles Sevilla Santa Justa

2.5 star property
2.5 km from Santa Clara
9.2 out of 10, Wonderful, (730)
"Perfect stay"
United States
Paola
The price is 2.252.864 ₫
2.478.150 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Ibis Styles Sevilla Santa Justa
Lobby lounge
Eurostars Guadalquivir

Eurostars Guadalquivir

4.0 star property
Los Remedios, 4.8 km from Santa Clara
9.4 out of 10, Exceptional, (514)
"Really nice hotel. Spacious rooms and fantastic balcony. "
United States
Eric
The price is 2.092.388 ₫
2.301.688 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Eurostars Guadalquivir
Seasonal outdoor pool
Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

4.0 star property
San Bartolomé, 3.3 km from Santa Clara
9.2 out of 10, Wonderful, (1004)
"The property had real historic character - in a great location with helpful and friendly staff "
United Kingdom
Caroline Jane
The price is 3.361.636 ₫
3.697.800 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Las Casas de la Judería, Sevilla Historic City Center
Lobby sitting area
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

4.0 star property
San Bartolomé, 3.3 km from Santa Clara
9.6 out of 10, Exceptional, (1078)
"A great spot with a wonderful staff and breakfast"
Canada
Don
The price is 3.415.395 ₫
3.756.935 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Hotel Amadeus Sevilla
View from property
Basic Hotel Doña Manuela

Basic Hotel Doña Manuela

2.0 star property
Santa Cruz, 3.3 km from Santa Clara
9.2 out of 10, Wonderful, (518)
"Clean good staff happy stay great location "
United Kingdom
A. Caroline
Basic Hotel Doña Manuela
Courtyard
Hotel Las Casas de El Arenal by Casas y Palacios

Hotel Las Casas de El Arenal by Casas y Palacios

4.0 star property
El Arenal, 4.1 km from Santa Clara
9.4 out of 10, Exceptional, (970)
"Amazing location and place to stay"
United States
Nina
The price is 3.557.154 ₫
3.912.869 ₫ total
includes taxes & fees
10 Dec - 11 Dec
Hotel Las Casas de El Arenal by Casas y Palacios
Exclusive Studio Suite | Private spa tub
Welldone Sierpes Boutique

Welldone Sierpes Boutique

2.0 star property
Alfalfa, 3.8 km from Santa Clara
9.4 out of 10, Exceptional, (564)
"Very clean and well kept. Quiet and had all the necessary amenities. Highly recommend if in this area. "
United States
ELIZABETH
The price is 2.668.870 ₫
2.935.757 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Welldone Sierpes Boutique
Outdoor pool, open 10:00 AM to 9:00 PM, pool umbrellas, pool loungers
Only YOU Hotel Sevilla

Only YOU Hotel Sevilla

5.0 star property
2.1 km from Santa Clara
9.8 out of 10, Exceptional, (570)
"What a good hotel, wish we had been staying for longer than the one night."
United Kingdom
Elisa
The price is 3.766.399 ₫
4.143.039 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Only YOU Hotel Sevilla
Reception
Adriano Hotel Boutique Sevilla

Adriano Hotel Boutique Sevilla

3.0 star property
El Arenal, 4.1 km from Santa Clara
9.4 out of 10, Exceptional, (1247)
"The best hotel, very nice a employees and clean rooms and excellent location ."
United States
Rosa
The price is 2.083.795 ₫
2.292.174 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Adriano Hotel Boutique Sevilla
Seasonal outdoor pool
Hotel Sevilla Center

Hotel Sevilla Center

4.0 star property
La Buhaira, 2.9 km from Santa Clara
9.2 out of 10, Wonderful, (1106)
"Good place to stay "
United States
Anatoliy
The price is 2.608.579 ₫
2.869.437 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Hotel Sevilla Center
Junior Suite | Minibar, in-room safe, desk, laptop workspace
Hotel Rey Alfonso X

Hotel Rey Alfonso X

4.0 star property
San Bartolomé, 3.3 km from Santa Clara
9.6 out of 10, Exceptional, (1112)
"Thoroughly enjoyed our stay and would highly recommend. Staff were very friendly and helpful and the breakfast very tasty! "
United Kingdom
John
The price is 9.208.173 ₫
10.128.990 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Hotel Rey Alfonso X
Interior
Welldone Quality - Crystal Pool

Welldone Quality - Crystal Pool

1.0 star property
Alfalfa, 3.8 km from Santa Clara
9.2 out of 10, Wonderful, (376)
"A modern and very comfortable place, very well located, close to everything and easy to get to the tourist attractions of the city of Seville"
United States
Andres
Welldone Quality - Crystal Pool
Spa
Eurostars Sevilla Boutique

Eurostars Sevilla Boutique

4.0 star property
Santa Cruz, 3.6 km from Santa Clara
9.0 out of 10, Wonderful, (488)
"Room was spotless, staff was courteous and location was perfect!"
United States
Andrean
The price is 2.761.719 ₫
3.037.922 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Eurostars Sevilla Boutique
Reception
Room Select Tetuán

Room Select Tetuán

3.0 star property
Alfalfa, 3.8 km from Santa Clara
8.8 out of 10, Excellent, (583)
"Wonderful staff and very clean and a wonderful location "
United States
Bohdonna
The price is 2.084.074 ₫
2.292.481 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Room Select Tetuán
Reception
Eurostars Al-Ándalus Palace

Eurostars Al-Ándalus Palace

4.0 star property
5.1 km from Santa Clara
8.6 out of 10, Excellent, (1147)
"The room was comfortable and clean!"
United States
Ileana
The price is 1.925.048 ₫
2.117.553 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Eurostars Al-Ándalus Palace
Junior Suite Terrace | Terrace/patio
Hotel Gravina 51

Hotel Gravina 51

4.0 star property
Museo, 4.3 km from Santa Clara
10.0 out of 10, Exceptional, (860)
"Clean room, very friendly staff, amenities and excellent breakfast."
United States
Lila
The price is 4.576.872 ₫
5.034.559 ₫ total
includes taxes & fees
10 Dec - 11 Dec
Hotel Gravina 51
Front of property
Hotel Monte Carmelo

Hotel Monte Carmelo

4.0 star property
Los Remedios, 4.5 km from Santa Clara
9.4 out of 10, Exceptional, (506)
"“The staff were super friendly and helpful, and they shared a great tip on getting access to the Alcazar. That was especially nice since we couldn’t find any tickets online"
Canada
Seyed Amir
The price is 2.483.061 ₫
2.731.336 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hotel Monte Carmelo
Outdoor pool, pool umbrellas, pool loungers
Melia Sevilla

Melia Sevilla

4.0 star property
3.3 km from Santa Clara
8.8 out of 10, Excellent, (1003)
"great stay"
United States
Helena
The price is 3.083.295 ₫
3.391.624 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Melia Sevilla
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Santa Clara

Find the best Santa Clara areas for the activities you enjoy most.

Historical Center

Known for its fantastic nightlife, stunning cathedral and popular shops, there's plenty to explore in Historical Center. Top attractions like Casa de la Memoria Cultural Center and Calle Sierpes are major draws. Catch the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop to see more of the city.

Santa Cruz

The fantastic nightlife and stunning cathedral are a few things travellers love about Santa Cruz. Check out Convent of the Incarnation or Giralda Tower while you're visiting, and jump aboard the metro at Puerta Jerez Tram Stop to get around town.

El Arenal

Travellers choose El Arenal for its abundant dining options. Hop aboard the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop and check out top sights like Teatro Maestranza.

Alfalfa

Unique features of Alfalfa include the bars and historical sites. Make a stop by Calle Sierpes or Casa de la Memoria Cultural Center while you're exploring the area.

Triana featuring a river or creek, street scenes and a house

Triana

Known for its abundant dining options and stunning river views, there's plenty to explore in Triana. Top attractions like Triana Market and Triana Bridge are major draws, and you can catch the metro at Plaza de Cuba Station or Cartuja Station to see more of the city.

Top Santa Clara Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What is Santa Clara like?
Santa Clara is a neighbourhood that travellers like for its shopping and restaurants. Consider a visit to Los Arcos Mall as part of your Santa Clara travel plans.
How many hotels are there in Santa Clara?
Expedia has 5 Santa Clara hotels and other accommodation options, and one might make a good home base for venturing out into the greater Seville area.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to get the best deals available in Santa Clara.
What can I see and do in this Seville neighbourhood?
Los Arcos Mall is an attraction you might want to check out while you're in Santa Clara. When you're sightseeing in Seville, Gran Plaza Sevilla and Centro Deportivo Amate are also worth a stop.