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13 Dec - 14 Dec
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14 Dec - 15 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for Santa Clara hotels

Terrace/patio
Catalonia Híspalis

Catalonia Híspalis

Catalonia Híspalis
3.0 star property
Santa Clara
7.4 out of 10, Good, (338)
"A lovely experience - the staff were courteous and the modern room was very clean. The breakfast which cost a little extra was delicious and the parking for a little extra was very secure. "
Canada
Gudrun
The price is 1.684.723 ₫
1.853.195 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Catalonia Híspalis
Porch
Eurostars Torre Sevilla

Eurostars Torre Sevilla

Eurostars Torre Sevilla
5.0 star property
Triana, 5.2 km from Santa Clara
9.2 out of 10, Wonderful, (857)
"One of the best hotels ever that I stayed in europe"
Canada
Lin
The price is 3.060.297 ₫
3.366.358 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Eurostars Torre Sevilla
Reception
Adriano Hotel Boutique Sevilla

Adriano Hotel Boutique Sevilla

Adriano Hotel Boutique Sevilla
3.0 star property
El Arenal, 4.1 km from Santa Clara
9.4 out of 10, Exceptional, (1247)
"The best hotel, very nice a employees and clean rooms and excellent location ."
United States
Rosa
The price is 2.097.024 ₫
2.306.726 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Adriano Hotel Boutique Sevilla
View from property
Hotel Murillo

Hotel Murillo

Hotel Murillo
2.0 star property
Santa Cruz, 3.5 km from Santa Clara
8.8 out of 10, Excellent, (1003)
"Staff was very friendly, perfect location can’t get any better than this hotel"
United States
Aldon
Hotel Murillo
Seasonal outdoor pool
Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center
4.0 star property
San Bartolomé, 3.3 km from Santa Clara
9.2 out of 10, Wonderful, (1004)
"The property had real historic character - in a great location with helpful and friendly staff "
United Kingdom
Caroline Jane
The price is 3.192.715 ₫
3.511.986 ₫ total
includes taxes & fees
13 Jan - 14 Jan 2026
Las Casas de la Judería, Sevilla Historic City Center
Lobby sitting area
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

Hotel Amadeus Sevilla
4.0 star property
San Bartolomé, 3.3 km from Santa Clara
9.6 out of 10, Exceptional, (1081)
"A great spot with a wonderful staff and breakfast"
Canada
Don
The price is 3.436.548 ₫
3.780.203 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Hotel Amadeus Sevilla
Rooftop terrace
Hotel Fernando III

Hotel Fernando III

Hotel Fernando III
4.0 star property
San Bartolomé, 3.3 km from Santa Clara
9.6 out of 10, Exceptional, (1528)
"Great location & staff were wonderful!"
United States
Fawn
The price is 9.574.043 ₫
10.531.447 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Hotel Fernando III
Outdoor pool, open 10:00 AM to 9:00 PM, pool umbrellas, pool loungers
Only YOU Hotel Sevilla

Only YOU Hotel Sevilla

Only YOU Hotel Sevilla
5.0 star property
2.1 km from Santa Clara
9.8 out of 10, Exceptional, (572)
"Absolutely loved the hotel. It was so beautiful, lovely staff, good location and breakfast was delicious!"
United Kingdom
Ana
The price is 3.653.410 ₫
4.018.751 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Only YOU Hotel Sevilla
Seasonal outdoor pool
Hotel Sevilla Center

Hotel Sevilla Center

Hotel Sevilla Center
4.0 star property
La Buhaira, 2.9 km from Santa Clara
9.2 out of 10, Wonderful, (1109)
"Great Staff , very helpful. Rooms spacious and clean."
United Kingdom
Robert
The price is 2.625.141 ₫
2.887.655 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Hotel Sevilla Center
Reception
Room Select Tetuán

Room Select Tetuán

Room Select Tetuán
3.0 star property
Alfalfa, 3.8 km from Santa Clara
8.8 out of 10, Excellent, (584)
"Wonderful staff and very clean and a wonderful location "
United States
Bohdonna
The price is 1.490.855 ₫
1.639.940 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Room Select Tetuán
Outdoor pool, pool umbrellas, pool loungers
Melia Sevilla

Melia Sevilla

Melia Sevilla
4.0 star property
3.3 km from Santa Clara
8.8 out of 10, Excellent, (1000)
"great stay"
United States
Helena
The price is 3.105.351 ₫
3.415.886 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Melia Sevilla
Lobby lounge
Eurostars Guadalquivir

Eurostars Guadalquivir

Eurostars Guadalquivir
4.0 star property
Los Remedios, 4.8 km from Santa Clara
9.4 out of 10, Exceptional, (515)
"Really nice hotel. Spacious rooms and fantastic balcony. "
United States
Eric
The price is 2.105.672 ₫
2.316.301 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Eurostars Guadalquivir
Restaurant
Hotel América Sevilla

Hotel América Sevilla

Hotel América Sevilla
4.0 star property
Encarnación-Regina, 3.9 km from Santa Clara
9.0 out of 10, Wonderful, (1003)
"We enjoyed our stay. Hotel was clean and easy access to all of the things we wanted to do while visiting. "
United States
Helen
The price is 1.933.059 ₫
2.126.365 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Hotel América Sevilla
Interior entrance
Hotel ILUNION Alcora Sevilla

Hotel ILUNION Alcora Sevilla

Hotel ILUNION Alcora Sevilla
4.0 star property
7.7 km from Santa Clara
8.4 out of 10, Very good, (1000)
"The hotel location and staff were really good and helpful. "
Canada
Awais
The price is 1.796.832 ₫
1.976.577 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Hotel ILUNION Alcora Sevilla
Minibar, in-room safe, desk, blackout curtains
NH Collection Sevilla

NH Collection Sevilla

NH Collection Sevilla
4.0 star property
3.1 km from Santa Clara
8.8 out of 10, Excellent, (1001)
"The hotel was very clean and well-maintained, with spotless rooms and fresh linens. Its convenient location made it easy to get around, and the staff provided excellent, friendly service throughout my stay. "
United Kingdom
Aristotle
The price is 2.218.033 ₫
2.439.836 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
NH Collection Sevilla
Seasonal outdoor pool, pool loungers, lifeguards on site
Melia Lebreros

Melia Lebreros

Melia Lebreros
4.0 star property
La Buhaira, 2 km from Santa Clara
9.0 out of 10, Wonderful, (1000)
"Excellent breakfast, rooms were clean and spotless "
United Kingdom
Peter
The price is 2.863.766 ₫
3.150.143 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Melia Lebreros
Exterior
Hilton Garden Inn Sevilla

Hilton Garden Inn Sevilla

Hilton Garden Inn Sevilla
4.0 star property
4 km from Santa Clara
9.0 out of 10, Wonderful, (1000)
"Can't wait to go again"
United States
Pedro
The price is 1.887.127 ₫
2.075.840 ₫ total
includes taxes & fees
13 Jan - 14 Jan 2026
Hilton Garden Inn Sevilla
Courtyard
El Rey Moro Hotel Boutique

El Rey Moro Hotel Boutique

El Rey Moro Hotel Boutique
4.0 star property
Santa Cruz, 3.5 km from Santa Clara
9.4 out of 10, Exceptional, (891)
"The location is A+! The staff is extremely attentive and knowledgeable their rooms where pristine and comfortable. The bed is very good. Breakfast is amazing. This hotel delivers a great experience."
United States
WALDECTOR
The price is 2.734.296 ₫
3.007.880 ₫ total
includes taxes & fees
17 Dec - 18 Dec
El Rey Moro Hotel Boutique
Premium bedding, minibar, in-room safe, desk
Hotel Giralda Center

Hotel Giralda Center

Hotel Giralda Center
4.0 star property
San Bernardo, 3.2 km from Santa Clara
9.6 out of 10, Exceptional, (1273)
"Great stay, clean, good location, highly recommend."
Canada
Geoffrey
The price is 3.150.169 ₫
3.465.186 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Hotel Giralda Center
Lobby sitting area
Petit Palace Marqués Santa Ana

Petit Palace Marqués Santa Ana

Petit Palace Marqués Santa Ana
4.0 star property
El Arenal, 3.9 km from Santa Clara
9.0 out of 10, Wonderful, (1002)
"Have stayed there before and will stay there again"
United States
Robert
The price is 2.577.411 ₫
2.835.152 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Petit Palace Marqués Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Clara

Find the best Santa Clara areas for the activities you enjoy most.

Historical Center

Known for its fantastic nightlife, stunning cathedral and popular shops, there's plenty to explore in Historical Center. Top attractions like Casa de la Memoria Cultural Center and Calle Sierpes are major draws. Catch the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop to see more of the city.

Santa Cruz

The fantastic nightlife and stunning cathedral are a few things travellers love about Santa Cruz. Check out Convent of the Incarnation or Giralda Tower while you're visiting, and jump aboard the metro at Puerta Jerez Tram Stop to get around town.

Alfalfa

Unique features of Alfalfa include the bars and historical sites. Make a stop by Calle Sierpes or Casa de la Memoria Cultural Center while you're exploring the area.

El Arenal

Travellers choose El Arenal for its abundant dining options. Hop aboard the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop and check out top sights like Teatro Maestranza.

Triana featuring a river or creek, street scenes and a house

Triana

Known for its abundant dining options and stunning river views, there's plenty to explore in Triana. Top attractions like Triana Market and Triana Bridge are major draws, and you can catch the metro at Plaza de Cuba Station or Cartuja Station to see more of the city.

Top Santa Clara Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What is Santa Clara like?
Santa Clara is a neighbourhood that travellers like for its shopping and restaurants. Consider a visit to Los Arcos Mall as part of your Santa Clara travel plans.
How many hotels are there in Santa Clara?
Expedia has 5 Santa Clara hotels and other accommodation options, and one might make a good home base for venturing out into the greater Seville area.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to get the best deals available in Santa Clara.
What can I see and do in this Seville neighbourhood?
Los Arcos Mall is an attraction you might want to check out while you're in Santa Clara. When you're sightseeing in Seville, Gran Plaza Sevilla and Centro Deportivo Amate are also worth a stop.