Search Luxury Hotels in Santee

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Santee Luxury Hotels

Tonight
3 Oct - 4 Oct
Tomorrow
4 Oct - 5 Oct
This weekend
3 Oct - 5 Oct
Next weekend
10 Oct - 12 Oct

Top Santee Luxury Hotels

Red Roof Inn Santee
Lobby

Red Roof Inn Santee

2.0 star property
6.6 out of 10, (626)
"Despite offering breakfast, it was lackluster "
The price is 1.847.456 ₫
2.050.676 ₫ total
includes taxes & fees
3 Nov - 4 Nov
Red Roof Inn Santee
Comfort Inn & Suites Santee
Lobby

Comfort Inn & Suites Santee

2.5 star property
8.0 out of 10, Very good, (1000)
"Great place to stay."
The price is 2.782.138 ₫
3.088.173 ₫ total
includes taxes & fees
12 Oct - 13 Oct
Comfort Inn & Suites Santee
Baymont by Wyndham Santee
Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free WiFi

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very good, (1345)
"A nice location, plenty of parking, nice that breakfast was included. "
The price is 1.979.436 ₫
2.197.176 ₫ total
includes taxes & fees
7 Oct - 8 Oct
Baymont by Wyndham Santee
Ramada by Wyndham Santee I-95
Property amenity

Ramada by Wyndham Santee I-95

2.0 star property
6.2 out of 10, (536)
"The grounds and property were clean and you could tell they take pride in what they're offering."
The price is 1.951.984 ₫
2.166.847 ₫ total
includes taxes & fees
5 Oct - 6 Oct
Ramada by Wyndham Santee I-95
Econo Lodge
Exterior

Econo Lodge

2.0 star property
6.4 out of 10, (309)
"Check in was easy."
The price is 1.559.476 ₫
1.731.018 ₫ total
includes taxes & fees
3 Nov - 4 Nov
Econo Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santee Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

Are you looking for a luxury hotel for your stay in Santee?
Let Expedia help you arrange your flight to Columbia, SC (CAE-Columbia Metropolitan) airport, and then choose from some places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to get what you want to make your stay relaxing and comfortable. If you want an upscale hotel with fine dining, a spa or several swimming pools, Expedia can help you find the best luxury hotel experience that Santee offers. During your visit, you might want to enjoy the restaurants and coffee shops which Santee is known for.
When can I expect good weather in Santee?
Planning for the weather is an important factor for making your trip to Santee a success, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Santee is 1397 mm.
What's there to see and do in Santee?
Enjoy all that Santee has to offer and visit Santee Cooper Country Club, Santee National Golf Club and Santee State Park. If you have a little extra time during your trip, you might want to make a stop at Lake Marion and Santee Town Hall.