Santo Domingo Holidays

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Where to stay in Santo Domingo

Find the best Santo Domingo areas and neighborhoods for the activities you enjoy most. Learn more about Santo Domingo
The Cibeles fountain in Mexico City is an exact replica of the Cibeles fountain that is located in the Plaza de Cibeles in Madrid, Spain

Roma Norte

Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like Avenida Insurgentes and MUCA Roma, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.

Find hotels in Roma Norte

Top hotels in Santo Domingo

Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico

4 out of 5
Mexico City
Fully refundable
The price is 3.058.380 ₫ per night from 10 Feb to 11 Feb
3.058.380 ₫
3.654.895 ₫ total
10 Feb - 11 Feb
includes taxes & fees
8.6/10 Excellent! (12,133 reviews)
The room was clean and comfortable but there was a children’s party going on somewhere nearby our room that I could hear loudly. They carried on until nearly 10pm. I was so tired I fell asleep anyway but some may be annoyed.

Reviewed on 27 Jan 2026

Camino Real Aeropuerto Mexico
Fiesta Americana Reforma

Fiesta Americana Reforma

4 out of 5
Paseo De La Reforma 80 Mexico City CDMX
Fully refundableReserve now, pay when you stay
The price is 3.264.022 ₫ per night from 22 Feb to 23 Feb
3.264.022 ₫
3.900.507 ₫ total
22 Feb - 23 Feb
includes taxes & fees
9.2/10 Wonderful! (4,275 reviews)
Great stay from staff to food to the room

Reviewed on 23 Jan 2026

Fiesta Americana Reforma
Historico Central Hotel

Historico Central Hotel

4 out of 5
Simón Bolívar No. 28 Mexico City Mexico City
Fully refundableReserve now, pay when you stay
The price is 3.776.939 ₫ per night from 24 Feb to 25 Feb
3.776.939 ₫
4.513.442 ₫ total
24 Feb - 25 Feb
includes taxes & fees
9.8/10 Exceptional! (2,403 reviews)
I loved my experiences at this hotel. The staff here are outstanding!! They'll do their best to make your stay a pleasurable experience. Manuel took such good care of me and is always so patient, welcoming and friendly. Daily breakfast and 24/7 coffee and sandwiches is super helpful when you are ...

Reviewed on 25 Jan 2026

Historico Central Hotel
See all 6,294 properties in Santo Domingo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santo Domingo holiday package cost?
We make it simple to see the world, with Santo Domingo packages starting from as low as . You'll have the flexibility to bundle your preferred airlines, hotels and car rental. For the ultimate getaway, why not add some activities and tours to your travel itinerary?
How do I get a cheap travel package to Santo Domingo?
Book everything all in one place with our Santo Domingo holiday packages. You'll discover deals on hotels, flights and more that'll keep your wallet happy and your spirit of adventure alive. And, with more than 550 partner airlines and 1null000null000 properties globally to choose from, there are endless opportunities to mix and match as you want.
Where should I stay in Santo Domingo?
Urban explorers come from every corner of the globe to see Basilica of Our Lady of Guadalupe and Zócalo in Santo Domingo. Book a hotel close to these top attractions and visit them at your leisure.
How far in advance should I book my Santo Domingo holiday?
It depends on the airline, but you can generally browse through international flights on Expedia nearly a year in advance. While it's generally recommended to book ahead of time, lucky travellers will sometimes find a cheaper ticket only weeks before the date of departure.
What does an Expedia Santo Domingo travel package include?
With Expedia, you can select a combination of hotels, car rentals and flights to build your ideal Santo Domingo package. Once you've made your booking, you can add on all the fun stuff like sightseeing tours and activities. Don't forget — the more you bundle, the more discounts you'll get!
What should I know before booking a Santo Domingo travel package?
When you book your hotels, flights and car rentals together, you'll enjoy amazing discounts. Whether you're planning a beach escape in a villa or want to stay in a comfortable hotel in the city, Expedia will help make it happen.
Can I choose my airline with a Santo Domingo Expedia holiday package?
Expedia has access to more than 550 airline partners globally, so you sure can! Just choose the carrier you want and craft your ideal Santo Domingo getaway.
If I'm not able to travel, can I cancel my Santo Domingo holiday package?
Don't stress if you're rethinking your Santo Domingo holiday package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur charges from your hotel, airline or car rental company. We totally understand your circumstances can suddenly change, so make your way to our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.

Popular places to visit

Basilica of Our Lady of Guadalupe showing a church or cathedral, religious elements and a square or plaza

Basilica of Our Lady of Guadalupe

You can learn more about the history of Mexico City when you visit a top site such as Basilica of Our Lady of Guadalupe. Experience the fascinating museums and acclaimed art galleries in this culturally rich area.

Basilica of Our Lady of Guadalupe
The Angel of Independence Monument featuring a monument, heritage elements and central business district

Angel of Independence Monument

You can learn more about the history of Mexico City when you visit a top site such as Angel of Independence Monument. Visit the shops and stunning cathedral in this vibrant area.

Angel of Independence Monument
Palacio de Bellas Artes showing night scenes, heritage architecture and a square or plaza

Palacio de Bellas Artes

Palacio de Bellas Artes is a popular museum in Mexico City with a rich history. Experience the fascinating museums and acclaimed art galleries in this vibrant area.

Palacio de Bellas Artes