Santo Domingo Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in Santo Domingo

Find the best Santo Domingo areas and neighborhoods for the activities you enjoy most. Learn more about Santo Domingo
An aerial view of a city with a central circular plaza, surrounded by buildings and trees.

Roma Norte

Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like Avenida Insurgentes and MUCA Roma, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.

Find hotels in Roma Norte

Top hotels in Santo Domingo

Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico

4 out of 5
Mexico City
Fully refundable
The price is 3.067.267 ₫ per night from 3 Aug to 4 Aug
3.067.267 ₫
3.665.383 ₫ total
3 Aug - 4 Aug
includes taxes & fees
8.8/10 Excellent! (13,400 reviews)
"Great stay would recommend"

Reviewed on 5 Jul 2026

Camino Real Aeropuerto Mexico
ULIV Mexico City

ULIV Mexico City

4.5 out of 5
235 Av. Insurgentes Sur Roma Norte Mexico City CDMX
The price is 2.392.708 ₫ per night from 13 Jul to 14 Jul
2.392.708 ₫
2.859.287 ₫ total
13 Jul - 14 Jul
includes taxes & fees
9/10 Wonderful! (1,679 reviews)
"The photos of the property included a balcony and our room’s balcony had a wall into the interior hallway. A little disappointing."

Reviewed on 4 Jul 2026

ULIV Mexico City
Historico Central Hotel

Historico Central Hotel

4 out of 5
Simón Bolívar No. 28 Mexico City Mexico City
Fully refundableReserve now, pay when you stay
The price is 3.438.632 ₫ per night from 13 Jul to 14 Jul
3.438.632 ₫
4.109.165 ₫ total
13 Jul - 14 Jul
includes taxes & fees
9.8/10 Exceptional! (2,381 reviews)
"Food service was perfect!"

Reviewed on 5 Jul 2026

Historico Central Hotel
See all 5,973 properties in Santo Domingo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santo Domingo holiday package cost?
We make it simple to see the world, with Santo Domingo packages starting from as low as . You'll have the flexibility to bundle your preferred airlines, hotels and car rental. For the ultimate getaway, why not add some activities and tours to your travel itinerary?
How do I get a cheap travel package to Santo Domingo?
Book everything all in one place with our Santo Domingo holiday packages. You'll discover deals on hotels, flights and more that'll keep your wallet happy and your spirit of adventure alive. And, with more than 550 partner airlines and 1null000null000 properties globally to choose from, there are endless opportunities to mix and match as you want.
Where should I stay in Santo Domingo?
Urban explorers come from every corner of the globe to see Basilica of Our Lady of Guadalupe and Zócalo in Santo Domingo. Book a hotel close to these top attractions and visit them at your leisure.
How far in advance should I book my Santo Domingo holiday?
It depends on the airline, but you can generally browse through international flights on Expedia nearly a year in advance. While it's generally recommended to book ahead of time, lucky travellers will sometimes find a cheaper ticket only weeks before the date of departure.
What does an Expedia Santo Domingo travel package include?
With Expedia, you can select a combination of hotels, car rentals and flights to build your ideal Santo Domingo package. Once you've made your booking, you can add on all the fun stuff like sightseeing tours and activities. Don't forget — the more you bundle, the more discounts you'll get!
What should I know before booking a Santo Domingo travel package?
When you book your hotels, flights and car rentals together, you'll enjoy amazing discounts. Whether you're planning a beach escape in a villa or want to stay in a comfortable hotel in the city, Expedia will help make it happen.
Can I choose my airline with a Santo Domingo Expedia holiday package?
Expedia has access to more than 550 airline partners globally, so you sure can! Just choose the carrier you want and craft your ideal Santo Domingo getaway.
If I'm not able to travel, can I cancel my Santo Domingo holiday package?
Don't stress if you're rethinking your Santo Domingo holiday package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur charges from your hotel, airline or car rental company. We totally understand your circumstances can suddenly change, so make your way to our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.