Search Hotels in South Medford, Boston

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Top Trending Hotels Near South Medford, Boston

DoubleTree by Hilton Boston North Shore

4.0 star property
24.2 km from South Medford
8.0 out of 10, Very good, (2284)
"Great stay!"
United States
Stephanie
The price is 2.572.502 ₫
2.873.484 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
DoubleTree by Hilton Boston North Shore

The Wylie Inn and Conference Center at Endicott College

3.5 star property
26.9 km from South Medford
9.2 out of 10, Wonderful, (1139)
"Clean room, great staff and service, very easy check in, I always stay here when visiting my son and daughter in law"
United States
Brian
The price is 3.203.104 ₫
3.577.867 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
The Wylie Inn and Conference Center at Endicott College

Hampton Inn & Suites Boston/Waltham

2.5 star property
13.2 km from South Medford
9.4 out of 10, Exceptional, (1567)
"Staff was friendly, place was clean, room was good. "
United States
Donald
The price is 2.256.673 ₫
2.520.703 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn & Suites Boston/Waltham

HYATT house Boston/Waltham

3.0 star property
12.6 km from South Medford
8.8 out of 10, Excellent, (1068)
"The Staff was great, the room was clean and comfortable and the breakfast was good! "
United States
Meridith
The price is 2.586.210 ₫
2.888.797 ₫ total
includes taxes & fees
19 Dec - 20 Dec
HYATT house Boston/Waltham

Nantasket Beach Resort

3.0 star property
24.8 km from South Medford
8.6 out of 10, Excellent, (1004)
"Lovely place to stay!"
United States
Patrice
The price is 3.141.151 ₫
4.062.274 ₫ total
includes taxes & fees
11 Dec - 12 Dec
Nantasket Beach Resort

The Cove At Salem

3.0 star property
22.9 km from South Medford
9.4 out of 10, Exceptional, (843)
"Room was spotless and very accommodating for our visit. "
United States
Jessica
The price is 3.084.471 ₫
3.445.354 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
The Cove At Salem

Sonesta Select Boston Danvers

3.0 star property
21.7 km from South Medford
8.6 out of 10, Excellent, (1005)
"Great place to stay"
United States
Juanita Diaz
The price is 2.841.931 ₫
3.174.437 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Sonesta Select Boston Danvers

Holiday Inn Express & Suites Boston South - Randolph by IHG

2.5 star property
27.2 km from South Medford
8.8 out of 10, Excellent, (1004)
"Everything was very satisfying good personal the service was excellent front desk help was amazing "
United States
Julio
The price is 2.319.944 ₫
2.591.377 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Boston South - Randolph by IHG

Seaport Hotel Boston

4.0 star property
8.2 km from South Medford
9.6 out of 10, Exceptional, (3786)
"Desk staff were fabulous, great location, clean and quiet "
United States
Arlene
The price is 4.854.205 ₫
5.784.536 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Seaport Hotel Boston

Hawthorne Hotel

3.5 star property
22 km from South Medford
9.4 out of 10, Exceptional, (1513)
"Great customer service, very clean rooms and amazing food! Will definitely be staying here again! "
United States
Samantha
Hawthorne Hotel

Hampton Inn Boston Woburn

2.5 star property
10.7 km from South Medford
9.2 out of 10, Wonderful, (1334)
"Very clean room and great staff!"
United States
Marcony
The price is 2.720.662 ₫
3.038.978 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Hampton Inn Boston Woburn

Omni Boston Hotel at the Seaport

5.0 star property
8.2 km from South Medford
9.2 out of 10, Wonderful, (4280)
"Awesome stay. "
United States
Xavier
The price is 4.553.839 ₫
6.377.502 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Omni Boston Hotel at the Seaport

Aloft by Marriott, Boston Seaport District

3.0 star property
8.4 km from South Medford
9.0 out of 10, Wonderful, (1372)
"Room was nice and clean reception staff was very friendly."
United States
Ede
The price is 2.715.389 ₫
3.929.497 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Aloft by Marriott, Boston Seaport District

The Westin Boston Seaport District

4.0 star property
8.3 km from South Medford
9.2 out of 10, Wonderful, (2317)
"Nice hotel and great location."
United States
James Earl
The price is 2.980.337 ₫
4.391.593 ₫ total
includes taxes & fees
22 Dec - 23 Dec
The Westin Boston Seaport District

The Revolution Hotel

3.5 star property
7.1 km from South Medford
9.0 out of 10, Wonderful, (2317)
"Clean, great staff, good food, great location!!!"
United States
Rafael
The Revolution Hotel

Hilton Garden Inn Tewksbury Andover

3.0 star property
28.6 km from South Medford
8.8 out of 10, Excellent, (864)
"A great place to stay while in town for the weekend. Would stay here again."
United States
Sarah
The price is 2.056.314 ₫
2.296.903 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Hilton Garden Inn Tewksbury Andover

Holiday Inn Express Boston - Saugus by IHG

3.0 star property
9.9 km from South Medford
8.6 out of 10, Excellent, (1009)
"Nice hotel near everything "
United States
Patricia
The price is 2.399.033 ₫
2.679.720 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Holiday Inn Express Boston - Saugus by IHG

Hampton Inn & Suites Boston Crosstown Center

3.0 star property
8.5 km from South Medford
7.8 out of 10, Good, (1429)
"Good front desk, better breakfast."
United States
HONGIL
The price is 2.298.854 ₫
2.677.014 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn & Suites Boston Crosstown Center

Lakeside Inn

2.0 star property
12.4 km from South Medford
7.6 out of 10, Good, (2323)
"Great value right on lakefront and super nice staff!! "
United States
jay
Lakeside Inn

Homewood Suites by Hilton Boston Seaport District

3.0 star property
8.8 km from South Medford
9.2 out of 10, Wonderful, (1378)
"Very clean and a family atmosphere"
United States
Maryanne
The price is 3.205.741 ₫
3.684.757 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Homewood Suites by Hilton Boston Seaport District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Medford

Find the best South Medford areas for the activities you enjoy most.

Downtown Boston

Known for its must-see aquarium and captivating waterfront views, there's plenty to explore in Downtown Boston. Check out top attractions like Boston Massacre Site and Old State House, and jump on the metro at State St. Station or Downtown Crossing Station to see more of the city.

Seaport District

Travellers to Seaport District praise its captivating waterfront views. If you've got some more time to explore, be sure to stop by Liberty Wharf and Leader Bank Pavilion.

Back Bay

Gourmet restaurants interesting history and top sights from Copley Square to Newbury Street – discover Back Bay, a destination also famous for its shopping.

Beacon Hill

Historical sites, shopping and restaurants highlight some notable features of Beacon Hill. Make a stop by Charles Street or Hatch Shell while you're visiting, and jump aboard the metro at Charles-MGH Station or Park St. Station to get around town.

North End

The ample dining options and captivating waterfront views are just a few popular features of the neighbourhood. Make a stop by New England Aquarium or Old North Church while you're visiting, and jump aboard the metro at Aquarium to get around town.

Top South Medford Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What is South Medford like?
Guests are sure to enjoy their time checking out all that Medford's South Medford neighbourhood has to offer.
How many hotels will I be able to find in the South Medford area?
If you're searching for places to stay in Medford, choose from one of Expedia's 13 hotels and other accommodation options in South Medford.
If I need to cancel my hotel reservation in South Medford, will I receive a refund?
Yes! Most room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals available in South Medford.
What can I see and do in this Medford neighbourhood?
Harvard Square, Powder House Square and Powder House Square are just a few of the places to visit in and around South Medford. While you're out sightseeing in Medford, make sure that you visit other sights such as Old Powder House or Old Ship Street Historic District.