Southeast Minnesota Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in Southeast Minnesota

Find the best Southeast Minnesota areas and neighborhoods for the activities you enjoy most. Learn more about Southeast Minnesota
Rochester showing skyline and a city

Downtown Rochester

2 out of top 10 points of interest in this area

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Art Center are top sights worth seeing.

Find hotels in Downtown Rochester

Top hotels in Southeast Minnesota

Kahler Grand Hotel
Kahler Grand Hotel
3 out of 5
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
8.2/10 Very Good! (1,413 reviews)
Bob
"Stay was fine"

Reviewed on 25 Jun 2025

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Kahler Grand Hotel
AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
3 out of 5
1625 Broadway Ave S, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is 1.974.087 ₫ per night from 29 Jun to 30 Jun
1.974.087 ₫
2.272.669 ₫ total
29 Jun - 30 Jun
includes taxes & fees
8/10 Very Good! (901 reviews)
"Great service"

Reviewed on 25 Jun 2025

AmericInn by Wyndham Rochester Near Mayo Clinic
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3 out of 5
110 Civic Center Drive NW, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is 2.794.840 ₫ per night from 6 Jul to 7 Jul
2.794.840 ₫
3.217.559 ₫ total
6 Jul - 7 Jul
includes taxes & fees
9/10 Wonderful! (949 reviews)
"Clean. Lovely welcome. Quiet."

Reviewed on 26 Jun 2025

Hyatt House Rochester/Mayo Clinic Area
See all 904 properties in Southeast Minnesota
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Southeast Minnesota holiday package cost?
Our Southeast Minnesota holiday packages, which start from as low as , are an ideal way to save. Select your favourite flights, hotels and rental cars to create a personalised itinerary.
How do I get a cheap travel package to Southeast Minnesota?
Bundle your flights and hotels with Expedia to save on your next exciting adventure. With more than 550 partner airlines and 1null000null000 properties across the globe, your Southeast Minnesota holiday package can be tailored exactly to suit your travel style. With all those extra dollars, why not add a few interesting activities and tours? It's an easy way to unlock even more discounts. The holiday you've always dreamed of in Southeast Minnesota is much closer than you thought!
What are the top hotels in Southeast Minnesota?
For hotels in Rochester with comfy beds and friendly service, you can't go past Kahler Inn and Suites - Mayo Clinic Area and Kahler Grand Hotel. If you plan to visit Lake City as well, you'll get a great night's sleep at Pet - Friendly Wabasha Studio: Boat or Peaceful Condo In Wabasha With Beautiful River Bluff Location - Lower Unit.
How far in advance should I book my Southeast Minnesota holiday?
Travellers are usually able to browse international airfares on Expedia within 12 months of the departure date. Booking last minute? With a little bit of luck, it's still possible to score an affordable ticket only weeks before your flight.
What does an Expedia Southeast Minnesota travel package include?
It's up to you! You can select from a range of Southeast Minnesota bundles, such as a flight, hotel and rental car. You can also book a hotel with a flight, or a rental car with a flight. Once you've made your booking, you can add the fun stuff like activities and experiences. Whatever your perfect Southeast Minnesota getaway looks like, you'll save!
What should I know before booking a Southeast Minnesota travel package?
Our prices are always low. However, you'll grab even more savings if you book your flights, hotels and car rentals together. With an Expedia travel package, you'll always get transparent pricing and lots of choice.
Can I choose my airline with a Southeast Minnesota Expedia holiday package?
Yes, you sure can. We have more than 550 partner airlines across the globe, so pick the carrier that fits your travel needs.
If I'm not able to travel, can I cancel my Southeast Minnesota holiday package?
It's impossible to predict what the future holds, so it's comforting to know that you can cancel or change your Southeast Minnesota holiday package. If your booking was made in the last 24 hours, you may be entitled to a refund. If it's an older booking, your hotel, airline or car rental company may charge a fee. Visit our Customer Service Portal for further details.

Popular places to visit

Niagara Cave

Niagara Cave

Commune with nature and explore the great outdoors at Niagara Cave during your travels in Harmony. Amble within the natural setting or visit the churches in this family-friendly area.

Niagara Cave

Mayo Clinic

If Mayo Clinic is what brings you to town, hopefully you'll have a chance to explore more of Rochester.

Mayo Clinic

Mayo Clinic Hospital - Saint Marys Campus

If Mayo Clinic Hospital - Saint Marys Campus is what brings you to town, hopefully you'll have a chance to explore more of Rochester.

Mayo Clinic Hospital - Saint Marys Campus