Downtown Clayton Travel Guide

St. Louis

Downtown Clayton


Top hotels in Downtown Clayton

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is 2.637.491 ₫ per night from 21 Jun to 22 Jun
2.637.491 ₫
3.078.955 ₫ total
21 Jun - 22 Jun
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
8.8/10 Excellent! (3,232 reviews)
"I had a very nice large room with a living room, large bathroom with tub and shower and a king bed. In all it was nice. The sheets seems old and cheap so that could be better. The breakfast was very good for a complimentary breakfast."

Reviewed on 18 Jun 2026

Clayton Plaza Hotel & Extended Stay
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave St. Louis MO
The price is 4.005.044 ₫ per night from 19 Jul to 20 Jul
4.005.044 ₫
4.715.459 ₫ total
19 Jul - 20 Jul
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the helpful staff ...
8.8/10 Excellent! (729 reviews)
"A wonderful stay. Room was clean and nice and had dinner at the on site restaurant and everything was delicious."

Reviewed on 17 Jun 2026

Le Méridien St. Louis Clayton
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5 out of 5
100 Carondelet Plaza St. Louis MO
The price is 13.122.702 ₫ per night from 21 Jun to 22 Jun
13.122.702 ₫
15.319.111 ₫ total
21 Jun - 22 Jun
includes taxes & fees
Stay at this luxury hotel in St. Louis. Enjoy 2 restaurants, 3 bars/lounges and breakfast (surcharge). Our guests praise the helpful staff and the room service ...
9.2/10 Wonderful! (570 reviews)
"We went on Memorial Day weekend which may have been why but there were so many weddings! (7) The car park was situated so that unless you walked outside and hiked the perimeter of the property you had to navigate through wedding guests to get to your car."

Reviewed on 5 Jun 2026

The Ritz-Carlton, St. Louis
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

3 out of 5
227 South Central Ave St. Louis MO
The price is 3.658.897 ₫ per night from 19 Jul to 20 Jul
3.658.897 ₫
4.271.324 ₫ total
19 Jul - 20 Jul
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park are ...
9/10 Wonderful! (318 reviews)
"The rooftop was a"

Reviewed on 15 Jun 2026

AC Hotel St. Louis Clayton
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
The price is 3.922.127 ₫ per night from 19 Jun to 20 Jun
3.922.127 ₫
4.625.327 ₫ total
19 Jun - 20 Jun
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (4,118 reviews)
"Room was fine. Had a fun view of the base of the Arch. Pillows and bedding seemed different than other Hyatt Regency hotels I’ve stayed at, not as comfortable and maybe out of a lesser material. The room felt clean and cared for just the same. The room was quiet and sleep was restful. Valet parking ..."

Reviewed on 18 Jun 2026

Hyatt Regency St. Louis at The Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
The price is 3.549.967 ₫ per night from 30 Jun to 1 Jul
3.549.967 ₫
4.150.613 ₫ total
30 Jun - 1 Jul
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the restaurant in their ...
8.8/10 Excellent! (2,008 reviews)
"Room was clean staff were lovely"

Reviewed on 17 Jun 2026

Pear Tree Inn St. Louis Near Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown Clayton

Find the best Downtown Clayton areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Central West End

The abundant dining options and forests are just a few top-rate features of the neighbourhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.



Downtown Clayton Travel Guide

Choose two or more items and save on your trip: