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19 Dec - 20 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for St. Luke's Hospital hotels

Breakfast, lunch, dinner served; American cuisine
Marriott St. Louis West

Marriott St. Louis West

Marriott St. Louis West
3.5 star property
1.1 km from St. Luke's Hospital
8.6 out of 10, Excellent, (1001)
"Needs to fix the heat "
United States
Falah
The price is 3.556.472 ₫
4.133.972 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Marriott St. Louis West
Lobby
Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
5.1 km from St. Luke's Hospital
9.6 out of 10, Exceptional, (1037)
"Absolutely amazing stay very nice play our family stays there every time very kid friendly"
United States
Matthew
The price is 3.420.687 ₫
3.967.513 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Drury Plaza Hotel St. Louis Chesterfield
Bar (on property)
Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield
3.0 star property
5 km from St. Luke's Hospital
9.6 out of 10, Exceptional, (1002)
"Wonderful staff, easy parking, nice breakfast, very comfortable room."
United States
Carole
The price is 3.236.745 ₫
3.754.237 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hyatt Place St. Louis/Chesterfield
Property amenity
Residence Inn by Marriott St. Louis Chesterfield

Residence Inn by Marriott St. Louis Chesterfield

Residence Inn by Marriott St. Louis Chesterfield
3.0 star property
7.3 km from St. Luke's Hospital
9.6 out of 10, Exceptional, (199)
"Very clean and safe place, wonderful location "
United States
Ashley
The price is 4.973.535 ₫
5.818.439 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Residence Inn by Marriott St. Louis Chesterfield
Indoor pool
Drury Plaza Hotel St. Louis Creve Coeur

Drury Plaza Hotel St. Louis Creve Coeur

Drury Plaza Hotel St. Louis Creve Coeur
3.0 star property
Creve Coeur, 5.3 km from St. Luke's Hospital
9.2 out of 10, Wonderful, (1000)
"Near hospitals and restaurants, clean linens, large breakfast choices, great parking. Most staff was very attentive. We felt safe at this location."
United States
Heather
The price is 3.019.383 ₫
3.509.631 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Drury Plaza Hotel St. Louis Creve Coeur
Exterior
AC Hotel by Marriott St. Louis Chesterfield

AC Hotel by Marriott St. Louis Chesterfield

AC Hotel by Marriott St. Louis Chesterfield
3.5 star property
5.9 km from St. Luke's Hospital
9.2 out of 10, Wonderful, (242)
"Newer hotel, very clean, up to date and in nice area. "
United States
Johnny
The price is 3.132.556 ₫
3.633.388 ₫ total
includes taxes & fees
25 Dec - 26 Dec
AC Hotel by Marriott St. Louis Chesterfield
Free daily buffet breakfast
Fairfield Inn & Suites by Marriott St. Louis Chesterfield

Fairfield Inn & Suites by Marriott St. Louis Chesterfield

Fairfield Inn & Suites by Marriott St. Louis Chesterfield
3.0 star property
4.2 km from St. Luke's Hospital
9.0 out of 10, Wonderful, (1002)
"Great room, friendly front desk staff"
United States
Roberta
The price is 2.550.796 ₫
2.958.616 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Fairfield Inn & Suites by Marriott St. Louis Chesterfield
Lobby
Residence Inn by Marriott St. Louis West County

Residence Inn by Marriott St. Louis West County

Residence Inn by Marriott St. Louis West County
3.0 star property
6.5 km from St. Luke's Hospital
9.2 out of 10, Wonderful, (244)
"We stayed here last weekend for the first time. The hotel was very clean and the staff was great!"
United States
Christopher
The price is 3.765.677 ₫
4.330.076 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Residence Inn by Marriott St. Louis West County
Lobby
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
14.9 km from St. Luke's Hospital
9.4 out of 10, Exceptional, (2750)
"Great place to stay before your early morning flight. "
United States
Henry
The price is 2.368.087 ₫
2.787.811 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Pear Tree Inn St. Louis Airport
Exterior
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
13.4 km from St. Luke's Hospital
9.4 out of 10, Exceptional, (1002)
"Good stay."
United States
Steven
The price is 2.916.755 ₫
3.352.139 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Country Inn & Suites by Radisson, St. Charles Historic District
Exterior
Courtyard by Marriott St. Louis West County

Courtyard by Marriott St. Louis West County

Courtyard by Marriott St. Louis West County
3.0 star property
6.5 km from St. Luke's Hospital
9.0 out of 10, Wonderful, (452)
"Very nice place to stay. "
United States
John
The price is 3.450.686 ₫
3.967.875 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Courtyard by Marriott St. Louis West County
Lobby
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
12.7 km from St. Luke's Hospital
9.6 out of 10, Exceptional, (1002)
"Staff and hotel were amazing"
United States
Allison
The price is 3.025.962 ₫
3.507.790 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Drury Plaza Hotel St. Louis St. Charles
Terrace/patio
Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
15 km from St. Luke's Hospital
9.4 out of 10, Exceptional, (838)
"Clean, would stay again."
United States
Eryka
The price is 2.661.762 ₫
3.265.482 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Courtyard by Marriott St. Louis Brentwood
Lobby
Residence Inn St Louis Westport

Residence Inn St Louis Westport

Residence Inn St Louis Westport
3.0 star property
7.8 km from St. Luke's Hospital
9.2 out of 10, Wonderful, (411)
"Great room for the price. Breakfast was amazing and the staff is super friendly! "
United States
Jimmy
The price is 3.765.677 ₫
4.367.732 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Residence Inn St Louis Westport
Indoor pool, outdoor pool
Drury Inn & Suites St. Louis Brentwood

Drury Inn & Suites St. Louis Brentwood

Drury Inn & Suites St. Louis Brentwood
3.0 star property
13.9 km from St. Luke's Hospital
9.6 out of 10, Exceptional, (1000)
"Clean, check in easy and efficient, quiet "
United States
Janice
The price is 3.368.057 ₫
4.000.406 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Drury Inn & Suites St. Louis Brentwood
Property entrance
The Wildwood Hotel

The Wildwood Hotel

The Wildwood Hotel
3.5 star property
13.6 km from St. Luke's Hospital
9.2 out of 10, Wonderful, (1604)
"Great place!"
United States
Biju
The Wildwood Hotel
Lobby
Fairfield Inn & Suites St Louis Westport

Fairfield Inn & Suites St Louis Westport

Fairfield Inn & Suites St Louis Westport
2.5 star property
7.8 km from St. Luke's Hospital
9.2 out of 10, Wonderful, (810)
"Everything was great "
United States
Alan
The price is 3.109.117 ₫
3.606.202 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Fairfield Inn & Suites St Louis Westport
Property amenity
Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur
3.0 star property
Creve Coeur, 5.6 km from St. Luke's Hospital
8.8 out of 10, Excellent, (1000)
"Clean room and very helpful staff"
United States
Amy
The price is 3.109.117 ₫
3.613.975 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Courtyard by Marriott St Louis Creve Coeur
Terrace/patio
TownePlace Suites by Marriott Brentwood

TownePlace Suites by Marriott Brentwood

TownePlace Suites by Marriott Brentwood
3.0 star property
14.7 km from St. Luke's Hospital
9.4 out of 10, Exceptional, (373)
"Clean Room GREAT place to stay! "
United States
Gary
The price is 3.105.170 ₫
3.795.303 ₫ total
includes taxes & fees
27 Dec - 28 Dec
TownePlace Suites by Marriott Brentwood
Exterior
Holiday Inn St. Louis - Creve Coeur by IHG

Holiday Inn St. Louis - Creve Coeur by IHG

Holiday Inn St. Louis - Creve Coeur by IHG
3.0 star property
5.3 km from St. Luke's Hospital
8.8 out of 10, Excellent, (351)
"Overall great stay, very clean and updated. Would stay again. "
United States
Alisa
The price is 3.079.908 ₫
3.682.095 ₫ total
includes taxes & fees
17 Jan - 18 Jan 2026
Holiday Inn St. Louis - Creve Coeur by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Luke's Hospital Hotel Reviews

Hotels near other St. Luke's Hospital attractions

Bellerive Country Club

Enjoy a round of golf in St. Louis at Bellerive Country Club. Experience the area's acclaimed theatre scene and entertainment choices.
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Bowlero Chesterfield

You can take time to visit Bowlero Chesterfield during your travels to Chesterfield. Visit the shops and top-notch restaurants in this family-friendly area.
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Frequently asked questions

What's the area like around St. Luke's Hospital?
St. Luke's Hospital is located in St. Louis. Travellers love the area for its great live music scene and top museums. You'll find 92 hotels and other accommodations within a few miles for a convenient home base.
How many hotels can I expect to find near St. Luke's Hospital?
Expedia has 92 hotels and other accommodation options a few miles from St. Luke's Hospital.
If I need to cancel the hotel reservation for my stay near St. Luke's Hospital, will I receive a refund?
Yes, most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get top deals close to St. Luke's Hospital.
What can I see and do near St. Luke's Hospital?
You'll want to browse the collections at Myseum, American Kennel Club Museum of the Dog and Historic Aircraft Restoration Museum. Get outside and spend some time strolling around Lou Fusz Soccer Complex, Sophia M. Sachs Butterfly House and Faust Park. Attractions like Chesterfield Arts and Chesterfield Amphitheater highlight the local culture.